Junhua Xie

Journal Article
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Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

Xiuming Liang, Dhanu Gupta, Junhua Xie, Elien Van Wonterghem (UGent) , Lien Van Hoecke (UGent) , Justin Hean, Zheyu Niu, Marziyeh Ghaeidamini, Oscar P. B. Wiklander, Wenyi Zheng, et al.

(2025) NATURE COMMUNICATIONS. 16(1).

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The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles

Junhua Xie, Lien Van Hoecke (UGent) , Elien Van Wonterghem (UGent) , Griet Van Imschoot (UGent) , Vanessa Andries (UGent) , Lars Vereecke (UGent) and Roosmarijn Vandenbroucke (UGent)

(2025) GUT MICROBES. 17(1).

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The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis

Femke Van Gaever (UGent) , Fleur Mingneau, Sam Vanherle, Yasmine Driege (UGent) , Mira Haegman (UGent) , Elien Van Wonterghem (UGent) , Junhua Xie, Roosmarijn Vandenbroucke (UGent) , Jerome J. A. Hendriks, Rudi Beyaert (UGent) , et al.

(2024) FRONTIERS IN IMMUNOLOGY. 15.

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The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice

Charysse Vandendriessche (UGent) , Arnout Bruggeman (UGent) , Joyce Foroozandeh (UGent) , Lien Van Hoecke (UGent) , Pieter Dujardin (UGent) , Junhua Xie, Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Jonas Castelein (UGent) , Cristiano Lucci, et al.

(2024) ENEURO. 11(3).

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An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology

Lien Van Hoecke (UGent) , Jonas Castelein (UGent) , Junhua Xie, Lore Van Acker (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Ine Vlaeminck, Daan Verhaege, Wouter Claeys (UGent) , Keimpe Wierda, et al.

(2024) BRAIN BEHAVIOR AND IMMUNITY. 117. p.122-134

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Bacterial extracellular vesicles : an emerging avenue to tackle diseases

Junhua Xie, Freddy Haesebrouck (UGent) , Lien Van Hoecke (UGent) and Roosmarijn Vandenbroucke (UGent)

(2023) TRENDS IN MICROBIOLOGY. 31(12). p.1206-1224

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Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology

Junhua Xie, Arnout Bruggeman (UGent) , Clint De Nolf (UGent) , Charysse Vandendriessche (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Lars Vereecke (UGent) and Roosmarijn Vandenbroucke (UGent)

(2023) EMBO JOURNAL. 42(17).

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Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling

Junhua Xie, Lien Cools (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Marie Pauwels, Ine Vlaeminck, Chloë De Witte (UGent) , Samir EL Andaloussi, Keimpe Wierda, Lies De Groef, et al.

(2023) JOURNAL OF EXTRACELLULAR VESICLES. 12(2).

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PhD Thesis

Studying the impact of the gastrointestinal bacteria on the brain, focusing on the blood-cerebrospinal fluid barrier and Alzheimer's disease

Junhua Xie

(2022)

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Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics

Marie Pauwels, Junhua Xie, Adam Ceroi (UGent) , Sriram Balusu, Jonas Castelein (UGent) , Elien Van Wonterghem (UGent) , Griet Van Imschoot (UGent) , Andrew Ward, Trevelyan R. Menheniott, Oskar Gustafsson, et al.

(2022) BIOMATERIALS. 290.

Academic Bibliography

Junhua Xie

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles

The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis

The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice

An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology

Bacterial extracellular vesicles : an emerging avenue to tackle diseases

Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology

Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling

Studying the impact of the gastrointestinal bacteria on the brain, focusing on the blood-cerebrospinal fluid barrier and Alzheimer's disease

Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics

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