prof. dr. Patrick Sips

Journal Article
A1
open access

The role of vascular smooth muscle cell plasticity in arterial remodelling and biomechanical failure : a numerical approach

Yousof Mohammad Assaad Abdel-Raouf (UGent) , Lauranne Maes (UGent) , Ludovica Maga, Julie De Backer (UGent) , Patrick Sips (UGent) , Mathias Peirlinck, Nele Famaey, Jay D. Humphrey and Patrick Segers (UGent)

(2026) PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES. 482(2336).

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Journal Article
A1
open access

Systematic disruption of zebrafish fibrillin genes identifies a translational zebrafish model for Marfan Syndrome

Karo De Rycke (UGent) , Marina Horvat (UGent) , Lisa Caboor (UGent) , Petra Vermassen (UGent) , Griet De Smet (UGent) , Sophie Lobbestael (UGent) , Marta Guerreiro Santana Ramos Da Silva (UGent) , Wouter Steyaert (UGent) , Matthias Van Impe (UGent) , Patrick Segers (UGent) , et al.

(2026) JACC-BASIC TO TRANSLATIONAL SCIENCE. 11(5).

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Toxicological assessment of cyclopiazonic acid and aflatoxin B1 : EFFECTS on zebrafish development and cardiac physiology

Victor Omondi Kagot, Marthe De Boevre (UGent) , Hanna De Saffel (UGent) , Patrick Sips (UGent) , Limbikani Matumba, Sheila Okoth, Sarah De Saeger (UGent) and Andy Willaert (UGent)

(2026) FOOD AND CHEMICAL TOXICOLOGY. 208.

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Journal Article
A1
open access

Evaluating variants of uncertain significance in adult zebrafish via prime editing : a proof of concept with a COL1A2 variant

Michiel Vanhooydonck (UGent) , Sophie Debaenst (UGent) , Eva Vanbelleghem (UGent) , Hanna De Saffel (UGent) , Delfien Syx (UGent) , Patrick Sips (UGent) , Paul Coucke (UGent) , Andy Willaert (UGent) and Bert Callewaert (UGent)

(2025) BMC MEDICAL GENOMICS. 19(1).

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Journal Article
A1
open access

Novel aortic dissection model links endothelial dysfunction and immune infiltration

Kenichi Kimura, Eri Motoyama, Sachiko Kanki, Keiichi Asano, Patrick Sips (UGent) , Md Al Amin Sheikh, Maria Thea Rane Dela Cruz Clarin, Erna Raja, Mariko Takeda, Ryutaro Ishii, et al.

(2025) CIRCULATION RESEARCH. 137(1). p.26-42

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A mutant zebrafish model in the search for new therapies for childhood chronic kidney disease

Pauline Van Wesemael (UGent) , Jolien De Velder (UGent) , Griet Glorieux (UGent) , Sophie Lobbestael (UGent) , Marina Horvat (UGent) , Patrick Sips (UGent) and Evelien Snauwaert (UGent)

(2025) BeSHG 25th Anniversary Conference 'Under pressure, the shaping of our genomes', Abstracts.

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Miscellaneous

Evaluating variants of uncertain significance in adult knock-in zebrafish : a proof of concept with a COL1A2 variant

Michiel Vanhooydonck (UGent) , Sophie Debaenst (UGent) , Eva Vanbelleghem (UGent) , Hanna De Saffel (UGent) , Delfien Syx (UGent) , Patrick Sips (UGent) , Paul Coucke (UGent) , Andy Willaert (UGent) and Bert Callewaert (UGent)

(2025) BioRxiv.

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Variant of uncertain significance testing in zebrafish : a proof of concept using a COL1A2 variant as example

Michiel Vanhooydonck (UGent) , Sophie Debaenst (UGent) , Eva Vanbelleghem (UGent) , Hanna De Saffel (UGent) , Delfien Syx (UGent) , Andy Willaert (UGent) , Patrick Sips (UGent) , Paul Coucke (UGent) and Bert Callewaert (UGent)

(2025) BeSHG 25th Anniversary Conference 'Under pressure, the shaping of our genomes', Abstracts.

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Journal Article
A1
open access

Modeling thoracic aortic genetic variants in the zebrafish : useful for predicting clinical pathogenicity?

Andrew Prendergast, Mary B. Sheppard, Jakub K. Famulski, Stefania Nicoli, Sandip Mukherjee, Patrick Sips (UGent) and John A. Elefteriades

(2025) FRONTIERS IN CARDIOVASCULAR MEDICINE. 12.

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Miscellaneous

Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture

Michiel Vanhooydonck (UGent) , Maxim Verlee (UGent) , Marta Guerreiro Santana Ramos Da Silva (UGent) , Lore Pottie (UGent) , Annekatrien Boel (UGent) , Matthias Van Impe (UGent) , Hanna De Saffel (UGent) , Lisa Caboor (UGent) , Piyanoot Tapaneeyaphan (UGent) , Anne Bonnin, et al.

(2024) BioRxiv.

Academic Bibliography

prof. dr. Patrick Sips

The role of vascular smooth muscle cell plasticity in arterial remodelling and biomechanical failure : a numerical approach

Systematic disruption of zebrafish fibrillin genes identifies a translational zebrafish model for Marfan Syndrome

Toxicological assessment of cyclopiazonic acid and aflatoxin B1 : EFFECTS on zebrafish development and cardiac physiology

Evaluating variants of uncertain significance in adult zebrafish via prime editing : a proof of concept with a COL1A2 variant

Novel aortic dissection model links endothelial dysfunction and immune infiltration

A mutant zebrafish model in the search for new therapies for childhood chronic kidney disease

Evaluating variants of uncertain significance in adult knock-in zebrafish : a proof of concept with a COL1A2 variant

Variant of uncertain significance testing in zebrafish : a proof of concept using a COL1A2 variant as example

Modeling thoracic aortic genetic variants in the zebrafish : useful for predicting clinical pathogenicity?

Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture

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