Bieke Bekaert

PhD Thesis

CRISPR/Cas9-based correction of infertility-related mutations in the germline : ready or not?

Bieke Bekaert (UGent)

(2023)

Journal Article
A1
open access

Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos

Bieke Bekaert (UGent) , Annekatrien Boel (UGent) , Lisa De Witte (UGent) , Winter Vandenberghe (UGent) , Mina Popovic, Panagiotis Stamatiadis, Gwenny Cosemans (UGent) , Lise Tordeurs (UGent) , Athina-Maria De Loore, Susana Marina Chuva de Sousa Lopes (UGent) , et al.

(2023) MOLECULAR THERAPY. 31(8). p.2326-2341

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Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos

Bieke Bekaert (UGent) , Annekatrien Boel (UGent) , Lisa De Witte (UGent) , Gwenny Cosemans (UGent) , Susana Marina Chuva de Sousa Lopes (UGent) , Björn Menten (UGent) and Björn Heindryckx (UGent)

(2022) FERTILITY AND STERILITY. In Fertility and Sterility 118(4, supplement). p.e100-e100

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Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells

Bieke Bekaert (UGent) , Annekatrien Boel (UGent) , Lisa De Witte (UGent) , Gwenny Cosemans (UGent) , Lise Tordeurs (UGent) , Athina-Maria De Loore, Susana Marina Chuva de Sousa Lopes (UGent) , Petra De Sutter (UGent) , Dominic Stoop (UGent) , Paul Coucke (UGent) , et al.

(2022) HUMAN REPRODUCTION. In Human Reproduction 37(supplement 1).

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CRISPR/Cas gene editing in the human germline

Bieke Bekaert (UGent) , Annekatrien Boel (UGent) , Gwenny Cosemans (UGent) , Lisa De Witte (UGent) , Björn Menten (UGent) and Björn Heindryckx (UGent)

(2022) SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 131. p.93-107

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Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI

Maoxing Tang, Annekatrien Boel (UGent) , Noemi Castelluccio (UGent) , Arantxa Cardona Barberán (UGent) , Antonia Christodoulaki (UGent) , Bieke Bekaert (UGent) , Mina Popovic, Frauke Vanden Meerschaut (UGent) , Petra De Sutter (UGent) , Björn Menten (UGent) , et al.

(2022) JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 39. p.609-618

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Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility

Bieke Bekaert (UGent) , Annekatrien Boel (UGent) , Mina Popovic, Panagiotis Stamatiadis, S M Chuva de Sousa Lopes, Petra De Sutter (UGent) , Björn Menten (UGent) , Dominic Stoop (UGent) , Paul Coucke (UGent) and Björn Heindryckx (UGent)

(2021) HUMAN REPRODUCTION. In Human Reproduction 36(Supplement 1). p.11-11

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Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin

Lise De Moor (UGent) , Jasper Smet, Magaly Plovyt (UGent) , Bieke Bekaert (UGent) , Chris Vercruysse (UGent) , Mahtab Asadian (UGent) , Nathalie De Geyter (UGent) , Sandra Van Vlierberghe (UGent) , Peter Dubruel (UGent) and Heidi Declercq (UGent)

(2021) BIOFABRICATION. 13(4).

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Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences

Panagiotis Stamatiadis, Annekatrien Boel (UGent) , Gwenny Cosemans (UGent) , Mina Popovic, Bieke Bekaert (UGent) , Ramesh Reddy Guggilla, Maoxing Tang, Petra De Sutter (UGent) , Filip Van Nieuwerburgh (UGent) , Björn Menten (UGent) , et al.

(2021) HUMAN REPRODUCTION. 36(5). p.1242-1252

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A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line

Bieke Bekaert (UGent) , Annekatrien Boel (UGent) , Lisa De Witte (UGent) , Mina Popovic, Ramesh Reddy Guggilla, Swati Mishra, Gwenny Cosemans (UGent) , Lise Tordeurs (UGent) , Susana Marina Chuva de Sousa Lopes (UGent) , Petra De Sutter (UGent) , et al.

(2020) 21th BeSHG meeting : Reproductive Genetics, Abstracts.

Academic Bibliography

Bieke Bekaert

CRISPR/Cas9-based correction of infertility-related mutations in the germline : ready or not?

Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos

Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos

Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells

CRISPR/Cas gene editing in the human germline

Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI

Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility

Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin

Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences

A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line

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