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ICP-MS : still gaining ground in biomedical/clinical applications
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- PhD Thesis
- open access
Combination of chemical derivatization and high-performance liquid chromatography coupled with inductively coupled plasma-(tandem) mass spectrometry (HPLC-ICP-MS/(MS)) for metabolite profiling of medical drugs
(2019) -
Development of a method for the quantitative metabolite profiling of pharmaceutical drugs using HPLC-ICP-MS following pre-column derivatization of their amino and hydroxyl groups using 4-aminopyridine as a model compound
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Population pharmacokinetics and simulations of imipenem in critically ill patients undergoing continuous renal replacement therapy
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High-performance liquid chromatography coupled to inductively coupled plasma - mass spectrometry (HPLC-ICP-MS) for quantitative metabolite profiling of non-metal drugs
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A pre-column derivatization method allowing quantitative metabolite profiling of carboxyl and phenolic hydroxyl group containing pharmaceuticals in human plasma via liquid chromatography-inductively coupled plasma-tandem mass spectrometry (LC-ICP-MS/MS)
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Concentrations, speciation, images and isotope ratios in biomedical/pharmaceutical research... ICP-MS delivers it all!
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Quantitative metabolite profiling of an amino group containing pharmaceutical in human plasma via precolumn derivatization and high-performance liquid chromatography-inductively coupled plasma mass spectrometry