Lien Van Hoecke

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Gut microbiota modulates CNS barrier function in murine model for multiple sclerosis

Junhua Xie, Marlies Burgelman (UGent) , Pieter Dujardin (UGent) , Jonas Castelein (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Hannah Lernout (UGent) , Sjoerd Schetters (UGent) , Charysse Vandendriessche (UGent) , Lien Van Hoecke (UGent) , et al.

(2025) FLUIDS AND BARRIERS OF THE CNS. 22(1).

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Mesenchymal stromal cell extracellular vesicles as immune modulators and drug carriers in neurodegenerative disorders

Lien Van Hoecke (UGent) , Cristiano Lucci (UGent) and Roosmarijn Vandenbroucke (UGent)

(2025) TRENDS IN NEUROSCIENCES. 48(11). p.919-934

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Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

Xiuming Liang, Dhanu Gupta, Junhua Xie, Elien Van Wonterghem (UGent) , Lien Van Hoecke (UGent) , Justin Hean, Zheyu Niu, Marziyeh Ghaeidamini, Oscar P. B. Wiklander, Wenyi Zheng, et al.

(2025) NATURE COMMUNICATIONS. 16(1).

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The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles

Junhua Xie, Lien Van Hoecke (UGent) , Elien Van Wonterghem (UGent) , Griet Van Imschoot (UGent) , Vanessa Andries (UGent) , Lars Vereecke (UGent) and Roosmarijn Vandenbroucke (UGent)

(2025) GUT MICROBES. 17(1).

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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease : lessons from animal studies

Wouter Claeys (UGent) , Anja Geerts (UGent) , Lien Van Hoecke (UGent) , Christophe Van Steenkiste and Roosmarijn Vandenbroucke (UGent)

(2025) NEURAL REGENERATION RESEARCH. 20(12). p.3461-3475

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Challenging the conventional wisdom : re-evaluating smpd3's role in extracellular vesicle biogenesis

Marlies Burgelman (UGent) , Pieter Dujardin (UGent) , Anthony Willems (UGent) , Tino Hochepied (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Lien Van Hoecke (UGent) , Charysse Vandendriessche (UGent) and Roosmarijn Vandenbroucke (UGent)

(2024) JOURNAL OF EXTRACELLULAR BIOLOGY. 3(11).

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A new MVA ancestor-derived oncolytic vaccinia virus induces immunogenic tumor cell death and robust antitumor immune responses

Juan J. Rojas, Lien Van Hoecke (UGent) , Miquel Conesa, Carmen Bueno-Merino, Ana del Canizo, Stephanie Riederer, Maria Barcia, Katrin Brosinski, Michael H. Lehmann, Asisa Volz, et al.

(2024) MOLECULAR THERAPY. 32(7). p.2406-2422

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Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease

Lien Van Hoecke (UGent) and Roosmarijn Vandenbroucke (UGent)

(2024) ACTA NEUROPATHOLOGICA COMMUNICATIONS. 12(1).

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The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice

Charysse Vandendriessche (UGent) , Arnout Bruggeman (UGent) , Joyce Foroozandeh (UGent) , Lien Van Hoecke (UGent) , Pieter Dujardin (UGent) , Junhua Xie, Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Jonas Castelein (UGent) , Cristiano Lucci, et al.

(2024) ENEURO. 11(3).

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An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology

Lien Van Hoecke (UGent) , Jonas Castelein (UGent) , Junhua Xie, Lore Van Acker (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Ine Vlaeminck, Daan Verhaege, Wouter Claeys (UGent) , Keimpe Wierda, et al.

(2024) BRAIN BEHAVIOR AND IMMUNITY. 117. p.122-134

Academic Bibliography

Lien Van Hoecke

Gut microbiota modulates CNS barrier function in murine model for multiple sclerosis

Mesenchymal stromal cell extracellular vesicles as immune modulators and drug carriers in neurodegenerative disorders

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles

Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease : lessons from animal studies

Challenging the conventional wisdom : re-evaluating smpd3's role in extracellular vesicle biogenesis

A new MVA ancestor-derived oncolytic vaccinia virus induces immunogenic tumor cell death and robust antitumor immune responses

Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease

The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice

An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology

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