Steven De Munck

Journal Article
A1
open access

Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries

Jan Félix (UGent) , Steven De Munck (UGent) , J. Fernando Bazan and Savvas Savvides (UGent)

(2025) PLOS BIOLOGY. 23(4).

Journal Article
A1
open access

Improving de novo protein binder design with deep learning

Nathaniel R. Bennett, Brian Coventry, Inna Goreshnik, Buwei Huang, Aza Allen, Dionne Vafeados, Ying Po Peng, Justas Dauparas, Minkyung Baek, Lance Stewart, et al.

(2023) NATURE COMMUNICATIONS. 14(1).

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PhD Thesis

Structure and mechanism of cytokine mediated activation of ALK family receptor tyrosine kinases

Steven De Munck (UGent)

(2021)

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Journal Article
A1
open access

Structural basis of cytokine-mediated activation of ALK family receptors

Steven De Munck (UGent) , Mathias Provost (UGent) , Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Félix (UGent) , Yehudi Bloch (UGent) , Omar Abdel-Wahab, J. Fernando Bazan, Akihide Yoshimi, et al.

(2021) NATURE. 600. p.143-147

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Journal Article
A1
open access

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Klaas Yperman, Anna Papageorgiou, Romain Merceron (UGent) , Steven De Munck (UGent) , Yehudi Bloch (UGent) , Dominique Eeckhout (UGent) , Qihang Jiang (UGent) , Pieter Tack (UGent) , Rosa Grigoryan, Thomas Evangelidis, et al.

(2021) NATURE COMMUNICATIONS. 12(1).

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Journal Article
A1
open access

Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis

Sandra Kozak, Yehudi Bloch (UGent) , Steven De Munck (UGent) , Aleksandra Mikula, Isabel Bento, Savvas Savvides (UGent) and Rob Meijers

(2020) ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY. 76. p.1244-1255

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Miscellaneous

Structure and assembly mechanism of the signaling complex mediated by human CSF-1 (vol 23, pg 1621, 2015)

Jan Félix (UGent) , Steven De Munck (UGent) , Kenneth Verstraete (UGent) , Leander Meuris (UGent) , Nico Callewaert (UGent) , Jonathan Elegheert (UGent) and Savvas Savvides (UGent)

(2020) STRUCTURE. 28(4).

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Journal Article
A1
open access

Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents

Yanlin Jian, Romain Merceron (UGent) , Steven De Munck (UGent) , He Eun Forbes, Fabian Hulpia (UGent) , Martijn Risseeuw (UGent) , Kristof Van Hecke (UGent) , Savvas Savvides (UGent) , Hélène Munier-Lehmann, Helena I. M. Boshoff, et al.

(2020) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 206.

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Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

Benjamin H Durham, Estibaliz Lopez Rodrigo, Jennifer Picarsic, David Abramson, Veronica Rotemberg, Steven De Munck (UGent) , Erwin Pannecoucke (UGent) , Sydney X Lu, Alessandro Pastore, Akihide Yoshimi, et al.

(2019) NATURE MEDICINE. 25(12). p.1839-1842

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Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Wim Dejonghe (UGent) , Isha Sharma (UGent) , Bram Denoo, Steven De Munck (UGent) , Qing Lu, Kiril Mishev (UGent) , Haydar Bulut, Evelien Mylle (UGent) , Riet De Rycke (UGent) , Mina Vasileva, et al.

(2019) NATURE CHEMICAL BIOLOGY. 15(6). p.641-649

Academic Bibliography

Steven De Munck

Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries

Improving de novo protein binder design with deep learning

Structure and mechanism of cytokine mediated activation of ALK family receptor tyrosine kinases

Structural basis of cytokine-mediated activation of ALK family receptors

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis

Structure and assembly mechanism of the signaling complex mediated by human CSF-1 (vol 23, pg 1621, 2015)

Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

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