ir. Wouter Van Loocke

Journal Article
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Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

André Pedro Pinto De Almeida (UGent) , Sara T'Sas (UGent) , Luca Pagliaro, Igor Fijalkowski (UGent) , Wouter Sleeckx (UGent) , Hannah Van Steenberge (UGent) , Raffaella Zamponi, Béatrice Lintermans (UGent) , Wouter Van Loocke (UGent) , Bruno Palhais (UGent) , et al.

(2024) HEMASPHERE. 8(3).

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Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma

Stéphane Van Haver (UGent) , Yujie Fan, Sarah-Lee Bekaert (UGent) , Celine Everaert (UGent) , Wouter Van Loocke (UGent) , Vittorio Zanzani (UGent) , Joke Deschildre, Ines Fernandez Maestre, Adrianna Amaro, Vanessa Vermeirssen (UGent) , et al.

(2024) ISCIENCE. 27(1).

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SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Siebe Loontiens (UGent) , Fanny De Vloed (UGent) , Sarah-Lee Bekaert (UGent) , Juliette Roels (UGent) , Suzanne Vanhauwaert (UGent) , Sara De Brouwer (UGent) , Ellen Sanders, A Berezovskaya, et al.

(2023) NATURE COMMUNICATIONS. 14(1).

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Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma

Lien Provez, Tom Putteman (UGent) , Mattias Landfors, Juliette Roels (UGent) , Lindy Reunes (UGent) , Sara T'Sas (UGent) , Wouter Van Loocke (UGent) , Béatrice Lintermans (UGent) , Stien De Coninck (UGent) , Morgan Thenoz, et al.

(2023) CANCERS. 15(3).

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IRF2 is required for development and functional maturation of human NK cells

Eva Persyn, Sigrid Wahlen, Laura Kiekens, Wouter Van Loocke (UGent) , Hannah Siwe (UGent) , Els Van Ammel (UGent) , Zenzi De Vos (UGent) , Filip Van Nieuwerburgh (UGent) , Patrick Matthys, Tom Taghon (UGent) , et al.

(2022) FRONTIERS IN IMMUNOLOGY. 13.

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RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho Nunes, Lisa Depestel (UGent) , Liselot Mus (UGent) , Kaylee M. Keller, Louis Delhaye (UGent) , Amber Louwagie (UGent) , Muhammad Rishfi (UGent) , Alex Whale, Neesha Kara, Simon R. Andrews, et al.

(2022) SCIENCE ADVANCES. 8(28).

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The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid Wahlen, Filip Matthijssens (UGent) , Wouter Van Loocke (UGent) , Sylvie Taveirne (UGent) , Laura Kiekens, Eva Persyn, Els Van Ammel (UGent) , Zenzi De Vos (UGent) , Stijn De Munter (UGent) , Patrick Matthys, et al.

(2022) ELIFE. 11.

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TXNIP promotes human NK cell development but is dispensable for NK cell functionality

Eva Persyn, Sigrid Wahlen, Laura Kiekens, Sylvie Taveirne (UGent) , Wouter Van Loocke (UGent) , Els Van Ammel (UGent) , Filip Van Nieuwerburgh (UGent) , Tom Taghon (UGent) , Bart Vandekerckhove (UGent) , Pieter Van Vlierberghe (UGent) , et al.

(2022) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 23(19).

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ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

Hila Fishman, Shreyas Madiwale, Ifat Geron, Vase Bari, Wouter Van Loocke (UGent) , Yael Kirschenbaum, Itamar Ganmore, Eitan Kugler, Avigail Rein-Gil, Gilgi Friedlander, et al.

(2022) BLOOD. 139(3). p.399-412

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MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation

Jolien De Wyn, Mark W. Zimmerman, Nina Weichert-Leahey, Carolina de Carvalho Nunes, Belamy B. Cheung, Brian J. Abraham, Anneleen Beckers (UGent) , Pieter-Jan Volders (UGent) , Bieke Decaesteker (UGent) , Daniel R. Carter, et al.

(2021) CANCERS. 13(19).

Academic Bibliography

ir. Wouter Van Loocke

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma

SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma

IRF2 is required for development and functional maturation of human NK cells

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

TXNIP promotes human NK cell development but is dispensable for NK cell functionality

ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation

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