Bram Laukens

Journal Article
A1
open access

GlycoVHH : optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery

Loes van Schie (UGent) , Wander Van Breedam (UGent) , Charlotte Roels (UGent) , Bert Schepens (UGent) , Martin Frank, Ahmadreza Mehdipour (UGent) , Bram Laukens, Wim Nerinckx (UGent) , Francis Santens (UGent) , Simon Devos (UGent) , et al.

(2023) MABS. 15(1).

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Miscellaneous

GlycoVHH : introducing N-glycans on the camelid VHH antibody scaffold : optimal sites and use for macrophage delivery

Loes van Schie (UGent) , Wander Van Breedam (UGent) , Charlotte Roels (UGent) , Bert Schepens (UGent) , Martin Frank, Ahmadreza Mehdipour (UGent) , Bram Laukens, Wim Nerinckx (UGent) , Francis Santens (UGent) , Simon Devos (UGent) , et al.

(2022) BioRXiv.

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Knockout of RSN1, TVP18 or CSC1-2 causes perturbation of Golgi cisternae in Pichia pastoris

Rochelle Aw, Charlot De Wachter (UGent) , Bram Laukens, Riet De Rycke (UGent) , Michiel De Bruyne (UGent) , David Bell, Nico Callewaert (UGent) and Karen M. Polizzi

(2021) TRAFFIC. 22(3). p.48-63

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Off-target glycans encountered along the synthetic biology route toward humanized N-glycans in Pichia pastoris

Bram Laukens, Pieter Jacobs, Katelijne Gheysen, José Martins (UGent) , Charlot De Wachter (UGent) , Paul Ameloot (UGent) , Willy Morelle, Jurgen Haustraete (UGent) , Jean-Christophe Renauld, Bart Samyn (UGent) , et al.

(2020) BIOTECHNOLOGY AND BIOENGINEERING. 117(8). p.2479-2488

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Journal Article
A1
open access

Yeast-secreted, dried and food-admixed monomeric IgA prevents gastrointestinal infection in a piglet model

Vikram Virdi (UGent) , Jorge Palací Bataller, Bram Laukens, Stefan Ryckaert (UGent) , Eric Cox (UGent) , Erik Vanderbeke, Anna Depicker (UGent) and Nico Callewaert (UGent)

(2019) NATURE BIOTECHNOLOGY. 37(5). p.527-530

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Journal Article
A1
open access

Optimized expression of the Starmerella bombicola lactone esterase in Pichia pastoris through temperature adaptation, codon-optimization and co-expression with HAC1

Stijn De Waele, Isabel Vandenberghe (UGent) , Bram Laukens, Sören Planckaert (UGent) , Stijn Verweire (UGent) , Inge Van Bogaert (UGent) , Wim Soetaert (UGent) , Bart Devreese (UGent) and Katarzyna Ciesielska (UGent)

(2018) PROTEIN EXPRESSION AND PURIFICATION. 143. p.62-70

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A simple colorimetric assay for measuring fructosamine 3 kinase activity

Justin C Cikomola, Antoine S Kishabongo, Karl Vandepoele (UGent) , Marieke De Mulder (UGent) , Philippe B Katchunga, Bram Laukens, Loes van Schie (UGent) , Hendrik Grootaert (UGent) , Nico Callewaert (UGent) , Marijn Speeckaert (UGent) , et al.

(2017) CLINICAL CHEMISTRY AND LABORATORY MEDICINE. 55(1). p.154-163

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PhD Thesis

N-glycosylation engineering in Pichia pastoris for protein therapeutics: advancing the GlycoSwitch and introducing GlycoDelete

Bram Laukens

(2016)

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Modular integrated secretory system engineering in Pichia pastoris to enhance G-protein coupled receptor expression

Katrien Claes (UGent) , Kristof Vandewalle (UGent) , Bram Laukens, Toon Laeremans, Olivier Vosters, Ingrid Langer, Marc Parmentier, Jan Steyaert and Nico Callewaert (UGent)

(2016) ACS SYNTHETIC BIOLOGY. 5(10). p.1070-1075

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Journal Article
A1
open access

A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris

Fabrice Cerini, Hubert Gaertner, Knut Madden, Ilya Tolstorukov, Scott Brown, Bram Laukens, Nico Callewaert (UGent) , Jay C Harner, Anna M Oommen, John T Harms, et al.

(2016) PROTEIN EXPRESSION AND PURIFICATION. 119. p.1-10

Academic Bibliography

Bram Laukens

GlycoVHH : optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery

GlycoVHH : introducing N-glycans on the camelid VHH antibody scaffold : optimal sites and use for macrophage delivery

Knockout of RSN1, TVP18 or CSC1-2 causes perturbation of Golgi cisternae in Pichia pastoris

Off-target glycans encountered along the synthetic biology route toward humanized N-glycans in Pichia pastoris

Yeast-secreted, dried and food-admixed monomeric IgA prevents gastrointestinal infection in a piglet model

Optimized expression of the Starmerella bombicola lactone esterase in Pichia pastoris through temperature adaptation, codon-optimization and co-expression with HAC1

A simple colorimetric assay for measuring fructosamine 3 kinase activity

N-glycosylation engineering in Pichia pastoris for protein therapeutics: advancing the GlycoSwitch and introducing GlycoDelete

Modular integrated secretory system engineering in Pichia pastoris to enhance G-protein coupled receptor expression

A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris

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