apr. Huybrecht T'jollyn
No current affiliation with UGent
- ORCID iD
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0000-0003-2101-9926
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PBPK and its virtual populations : the impact of physiology on pediatric pharmacokinetic predictions of tramadol
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A physiologically based pharmacokinetic perspective on the clinical utility of albumin-based dose adjustments in critically ill patients
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Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound
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- PhD Thesis
- open access
Characterizing hepatic clearance in early life : PBPK as modelling tool and tramadol as guide
(2016) -
Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation
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- Journal Article
- A1
- open access
Physiology-based IVIVE predictions of tramadol from in vitro metabolism data
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- Journal Article
- A1
- open access
Moxifloxacin dosing in post-bariatric surgery patients
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- Conference Paper
- C3
- open access
Moxifloxacin dosing in post-bariatric surgery patients: another nail in the coffin of the 'one dose fits all' paradigm
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Development and validation of a fast and uniform approach to quantify β-lactam antibiotics in human plasma by solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry
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Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity