dr. apr. Karen Peynshaert

Journal Article
A1
open access

Photodisruption of the inner limiting membrane promotes retinal engraftment of stem-cell derived retinal ganglion cells

Emma De Coster (UGent) , Kaat De Clerck (UGent) , Chloë De Clercq (UGent) , Weiran Li (UGent) , Deep Punj (UGent) , Bernd Vanmeerhaeghe (UGent) , Jonie Verdonck (UGent) , Stefaan De Smedt (UGent) , Kevin Braeckmans (UGent) , Hanieh Hadady, et al.

(2026) INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 67(2).

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Journal Article
A1
open access

Advancing nanoparticle delivery studies : flow cytometry-based quantification of nanoparticle uptake and transfection in retinal tissue

Luca Paoletti (UGent) , Kaat De Clerck (UGent) , Emma De Coster (UGent) , Pietro Matricardi, Katrien Remaut (UGent) and Karen Peynshaert (UGent)

(2026) DRUG DELIVERY AND TRANSLATIONAL RESEARCH. 16(4). p.1301-1318

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Overcoming size barriers in retinal gene therapy via lipid nanoparticle-mediated delivery of full-length eys DNA

Sarah Goddaer (UGent) , Emma De Coster (UGent) , Elise Callens (UGent) , Emma Van Caenegem, Olivier Van den Heule, Rob W. J. Collin, Karen Peynshaert (UGent) , Filip Van Nieuwerburgh (UGent) , Kevin Braeckmans (UGent) and Katrien Remaut (UGent)

(2026) DRUG DELIVERY AND TRANSLATIONAL RESEARCH.

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Strategic lipid nanoparticle design dictates retinal delivery post inner limiting membrane disruption

Kaat De Clerck (UGent) , Emma De Coster (UGent) , Luca Paoletti (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Karen Peynshaert (UGent)

(2026) DRUG DELIVERY AND TRANSLATIONAL RESEARCH. 16(6). p.1860-1876

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Journal Article
A1
open access

Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye

Weiran Li (UGent) , Helena Vanluchene, Laura Raes, Karen Peynshaert (UGent) , Liene Veys, Sofía González Hernández (UGent) , Emily De Lombaerde, Bruno De Geest (UGent) , Niek Sanders (UGent) , Lieve Moons, et al.

(2025) JOURNAL OF CONTROLLED RELEASE. 385.

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Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis

An-Katrien Minnaert, Van-Phuc Nguyen, Aranit Harizaj (UGent) , Ilia Goemaere (UGent) , Bart Van Puyvelde (UGent) , Maarten Dhaenens (UGent) , Félix Sauvage (UGent) , Dieter Deforce (UGent) , Stefano Salmaso, Paolo Caliceti, et al.

(2025) JOURNAL OF CONTROLLED RELEASE. 383.

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Toward successful retinal drug delivery after intravitreal injection : current strategies to overcome the inner limiting membrane

Kaat De Clerck (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Karen Peynshaert (UGent)

(2025) JOURNAL OF CONTROLLED RELEASE. 384.

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Journal Article
A1
open access

Less is more : self-amplifying mRNA becomes self-killing upon dose escalation in immune-competent retinal cells

Helena Vanluchene, Oriane Gillon (UGent) , Karen Peynshaert (UGent) , Stefaan De Smedt (UGent) , Niek Sanders (UGent) , Koen Raemdonck (UGent) and Katrien Remaut (UGent)

(2024) EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 196.

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Every nano-step counts : a critical reflection on do’s and don’ts in researching nanomedicines for retinal gene therapy

Karen Peynshaert (UGent) , Joke Devoldere (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2023) EXPERT OPINION ON DRUG DELIVERY. 20(2). p.259-271

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ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery

Karen Peynshaert (UGent) , Helena Vanluchene, Kaat De Clerck (UGent) , An-Katrien Minnaert, Morgane Verhoeven, Noémie Gouspillou (UGent) , Nezahat Bostan, Toshio Hisatomi, Geraldine Accou (UGent) , Félix Sauvage (UGent) , et al.

(2022) JOURNAL OF CONTROLLED RELEASE. 349. p.315-326

Academic Bibliography

dr. apr. Karen Peynshaert

Photodisruption of the inner limiting membrane promotes retinal engraftment of stem-cell derived retinal ganglion cells

Advancing nanoparticle delivery studies : flow cytometry-based quantification of nanoparticle uptake and transfection in retinal tissue

Overcoming size barriers in retinal gene therapy via lipid nanoparticle-mediated delivery of full-length eys DNA

Strategic lipid nanoparticle design dictates retinal delivery post inner limiting membrane disruption

Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye

Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis

Toward successful retinal drug delivery after intravitreal injection : current strategies to overcome the inner limiting membrane

Less is more : self-amplifying mRNA becomes self-killing upon dose escalation in immune-competent retinal cells

Every nano-step counts : a critical reflection on do’s and don’ts in researching nanomedicines for retinal gene therapy

ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery

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