Séan Mc Cafferty

Journal Article
A1
open access

A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity

Séan Mc Cafferty (UGent) , A. K. M. Ashiqul Haque, Aster Vandierendonck, Brian Weidensee, Magalie Plovyt, Magdalena Stuchlikova, Nathalie François (UGent) , Sophie Valembois, Leo Heyndrickx, Johan Michiels, et al.

(2022) MOLECULAR THERAPY. 30(9). p.2968-2983

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PhD Thesis

The self-amplifying RNA platform for vaccination and in vivo controllable production of therapeutic proteins

Séan Mc Cafferty (UGent)

(2022)

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In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

Séan Mc Cafferty (UGent) , Joyca De Temmerman, Tasuku Kitada, Jacob R. Becraft, Ron Weiss, Darrell J. Irvine, Mathias Devreese (UGent) , Siegrid De Baere (UGent) , Francis Combes (UGent) and Niek Sanders (UGent)

(2021) MOLECULAR THERAPY. 29(3). p.1164-1173

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Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Zifu Zhong (UGent) , Séan Mc Cafferty (UGent) , Lisa Opsomer (UGent) , Haixiu Wang (UGent) , Hanne Huysmans, Joyca De Temmerman, Stefan Lienenklaus, João Portela Catani (UGent) , Francis Combes (UGent) and Niek Sanders (UGent)

(2021) MOLECULAR THERAPY. 29(4). p.1370-1381

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Journal Article
A1
open access

Immunogenicity and protection efficacy of a naked self-replicating mRNA-based Zika virus vaccine

Zifu Zhong (UGent) , João Paulo Portela Catani, Séan Mc Cafferty (UGent) , Liesbeth Couck (UGent) , Wim Van Den Broeck (UGent) , Nina Gorlé, Roosmarijn Vandenbroucke (UGent) , Bert Devriendt (UGent) , Sebastian Ulbert, Lieselotte Cnops, et al.

(2019) VACCINES. 7(3).

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open access

Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA

Hanne Huysmans, Joyca De Temmerman, Zifu Zhong (UGent) , Séan Mc Cafferty (UGent) , Francis Combes (UGent) , Freddy Haesebrouck (UGent) and Niek Sanders (UGent)

(2019) MOLECULAR THERAPY-NUCLEIC ACIDS. 17. p.388-395

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open access

Mononuclear but not polymorphonuclear phagocyte depletion increases circulation times and improves mammary tumor-homing efficiency of donor bone marrow-derived monocytes

Francis Combes (UGent) , Alexandros Marios Sofias, Séan Mc Cafferty (UGent) , Hanne Huysmans, Joyca De Temmerman, Sjoerd Hak, Evelyne Meyer (UGent) and Niek Sanders (UGent)

(2019) CANCERS. 11(11).

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Journal Article
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open access

Expression kinetics and innate immune response after electroporation and LNP-mediated delivery of a self-amplifying mRNA in the skin

Hanne Huysmans, Zifu Zhong (UGent) , Joyca De Temmerman, Barbara L Mui, Ying K Tam, Séan Mc Cafferty (UGent) , Arlieke Gitsels, Daisy Vanrompay (UGent) and Niek Sanders (UGent)

(2019) MOLECULAR THERAPY-NUCLEIC ACIDS. 17. p.867-878

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Bovine embryo-secreted microRNA-30c is a potential non-invasive biomarker for hampered preimplantation developmental competence

Xiaoyuan Lin, Evy Beckers, Séan Mc Cafferty (UGent) , Yannick Gansemans (UGent) , Katarzyna Szymańska-Vandendriessche, Krishna Chaitanya Pavani (UGent) , João Portela Catani (UGent) , Filip Van Nieuwerburgh (UGent) , Dieter Deforce (UGent) , Petra De Sutter (UGent) , et al.

(2019) FRONTIERS IN GENETICS. 10.

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mRNA therapeutics deliver a hopeful message

Zifu Zhong (UGent) , Séan Mc Cafferty (UGent) , Francis Combes (UGent) , Hanne Huysmans, Joyca De Temmerman, Arlieke Gitsels, Daisy Vanrompay (UGent) , João Portela Catani (UGent) and Niek Sanders (UGent)

(2018) NANO TODAY. 23. p.16-39

Academic Bibliography

Séan Mc Cafferty

A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity

The self-amplifying RNA platform for vaccination and in vivo controllable production of therapeutic proteins

In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Immunogenicity and protection efficacy of a naked self-replicating mRNA-based Zika virus vaccine

Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA

Mononuclear but not polymorphonuclear phagocyte depletion increases circulation times and improves mammary tumor-homing efficiency of donor bone marrow-derived monocytes

Expression kinetics and innate immune response after electroporation and LNP-mediated delivery of a self-amplifying mRNA in the skin

Bovine embryo-secreted microRNA-30c is a potential non-invasive biomarker for hampered preimplantation developmental competence

mRNA therapeutics deliver a hopeful message

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