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Ottergemsesteenweg 460
9000 Gent - Eline.Pottie@UGent.be
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A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
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An enlightening trip through psychedelic and purinergic signaling
(2022) -
- Journal Article
- A1
- open access
The P2Y(2) receptor C-terminal tail modulates but is dispensable for beta-arrestin recruitment
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Serotonin 2A receptor (5-HT2AR) activation by 25H-NBOMe positional isomers : in vitro functional evaluation and molecular docking
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Synthesis and functional characterization of 2-(2,5-dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) positional isomers
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- Journal Article
- A1
- open access
In vitro structure-activity relationship determination of 30 psychedelic new psychoactive substances by means of beta-arrestin 2 recruitment to the serotonin 2A receptor
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- Journal Article
- A1
- open access
Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of beta-arrestin 2 and miniG alpha(q) bioassays
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Assessment of biased agonism at the A(3) adenosine receptor using beta-arrestin and miniG alpha(i) recruitment assays
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Setup of a serotonin 2A receptor (5-HT2AR) bioassay : demonstration of its applicability to functionally characterize hallucinogenic new psychoactive substances and an explanation why 5-HT2AR bioassays are not suited for universal activity-based screening of biofluids for new psychoactive substances
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In vitro and ex vivo delivery of tailored siRNA-nanoliposomes for E2F1 silencing as a potential therapy for colorectal cancer