dr. Steven Timmermans

Journal Article
A1
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HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

Céline Van Dender (UGent) , Steven Timmermans (UGent) , Maxime Roes (UGent) , Madeleine Hellemans (UGent) , Elise Moens (UGent) , Louise Nuyttens (UGent) , Maarten Claes (UGent) , Bart Roman (UGent) , Karolien De Bosscher (UGent) , Jolien Vandewalle (UGent) , et al.

(2025) FRONTIERS IN IMMUNOLOGY. 16.

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Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration

Evelien Van Dijck, Steven Van Laere, Emilie Logie, Steven Timmermans (UGent) , Erik Fransen, Joe Ibrahim, Timothy J. Kendall, Jonathan A. Fallowfield, Ligia M. Mateiu, Claude Libert (UGent) , et al.

(2025) CLINICAL EPIGENETICS. 17(1).

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Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Natalia Garcia Gonzalez (UGent) , Charlotte Wallaeys (UGent) , Wendy Toussaint (UGent) , Tino Hochepied (UGent) , Sylviane Dewaele (UGent) , Somara De Beul (UGent) , Robin Van Loke (UGent) , Jolien Vandewalle (UGent) , Steven Timmermans (UGent) and Claude Libert (UGent)

(2025) FRONTIERS IN IMMUNOLOGY. 16.

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Modulation of glucocorticoid receptor function under iron overload

Wanting Zhu (UGent) , Tineke Vanderhaeghen (UGent) , Steven Timmermans (UGent) , Jolien Vandewalle (UGent) , Melanie Eggermont (UGent) , Nicolette J. D. Verhoog and Claude Libert (UGent)

(2025) FRONTIERS IN IMMUNOLOGY. 16.

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Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

Steven Timmermans (UGent) , Charlotte Wallaeys (UGent) , Somara De Beul (UGent) , Natalia Garcia Gonzalez (UGent) and Claude Libert (UGent)

(2025) FRONTIERS IN IMMUNOLOGY. 16.

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Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

Fëllanza Halimi (UGent) , Tineke Vanderhaeghen (UGent) , Steven Timmermans (UGent) , Siska Croubels (UGent) , Claude Libert (UGent) and Jolien Vandewalle (UGent)

(2024) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 25(20).

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A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Céline Van Dender (UGent) , Steven Timmermans (UGent) , Ville Paakinaho, Tineke Vanderhaeghen (UGent) , Jolien Vandewalle (UGent) , Maarten Claes (UGent) , Bruno Garcia, Bart Roman (UGent) , Jan De Waele (UGent) , Siska Croubels (UGent) , et al.

(2024) EMBO MOLECULAR MEDICINE. 16(10). p.2485-2515

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Identification and characterization of multiple Paneth cell types in the mouse small intestine

Steven Timmermans (UGent) , Charlotte Wallaeys (UGent) , Natalia Garcia Gonzalez (UGent) , Lotte Pollaris (UGent) , Yvan Saeys (UGent) and Claude Libert (UGent)

(2024) CELLS. 13(17).

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Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte Wallaeys (UGent) , Natalia Garcia Gonzalez (UGent) , Steven Timmermans (UGent) , Jolien Vandewalle (UGent) , Tineke Vanderhaeghen (UGent) , Somara De Beul (UGent) , Hester Dufoor (UGent) , Melanie Eggermont (UGent) , Elise Moens (UGent) , Victor Bosteels, et al.

(2024) CELL HOST & MICROBE. 32(10). p.1725-1743

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Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Claudia Theys, Tineke Vanderhaeghen (UGent) , Evelien Van Dijck, Cedric Peleman, Anne Scheepers, Joe Ibrahim, Ligia Mateiu, Steven Timmermans (UGent) , Tom Vanden Berghe (UGent) , Sven M. Francque, et al.

(2024) FRONTIERS IN MOLECULAR MEDICINE. 3.

Academic Bibliography

dr. Steven Timmermans

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration

Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Modulation of glucocorticoid receptor function under iron overload

Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Identification and characterization of multiple Paneth cell types in the mouse small intestine

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

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