dr. Koen Sedeyn

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Immunogenicity and protection of octavalent influenza vaccine candidates using adjuvanted proteins or mRNA-LNPs in naïve mice

João Portela Catani (UGent) , Anouk Smet (UGent) , Tine Ysenbaert (UGent) , Laura Amelinck (UGent) , Koen Sedeyn (UGent) , Xavier Saelens (UGent) and Thorsten U. Vogel

(2026) NPJ VACCINES. 11(1).

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Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base

Sieglinde De Cae (UGent) , Inge Van Molle, Loes van Schie (UGent) , Sophie R. Shoemaker, Julie Deckers (UGent) , Nincy Debeuf (UGent) , Sahine Lameire (UGent) , Wim Nerinckx (UGent) , Kenny Roose (UGent) , Daria Fijalkowska (UGent) , et al.

(2025) NATURE COMMUNICATIONS. 16(1).

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Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline : caution is warranted

Delphine Diana Acar, Wojciech Witkowski (UGent) , Magdalena Wejda (UGent) , Ruifang Wei (UGent) , Tim Desmet (UGent) , Bert Schepens (UGent) , Sieglinde De Cae (UGent) , Koen Sedeyn (UGent) , Hannah Eeckhaut (UGent) , Daria Fijalkowska (UGent) , et al.

(2024) EBIOMEDICINE. 100.

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Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa

Jozefien Declercq (UGent) , Sarah Gerlo (UGent) , Sharon Van Nevel, Natalie De Ruyck (UGent) , Gabriële Holtappels (UGent) , Liesbeth Delesie (UGent) , Els Tobback (UGent) , Inés Lammens (UGent) , Nikita Gerebtsov (UGent) , Koen Sedeyn (UGent) , et al.

(2024) SCIENCE TRANSLATIONAL MEDICINE. 16(770).

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Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins

Livija Tušar, Jure Loboda, Francis Impens (UGent) , Piotr Sosnowski, Emmy Van Quickelberghe (UGent) , Robert Vidmar, Hans Demol (UGent) , Koen Sedeyn (UGent) , Xavier Saelens (UGent) , Matej Vizovišek, et al.

(2023) COMMUNICATIONS BIOLOGY. 6(1).

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An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25

Tessa Van Royen, Koen Sedeyn (UGent) , Georgios Moschonas (UGent) , Wendy Toussaint (UGent) , M Vuylsteke, Delphi Van Haver (UGent) , Francis Impens (UGent) , Sven Eyckerman (UGent) , Irma Lemmens (UGent) , Jan Tavernier (UGent) , et al.

(2022) JOURNAL OF VIROLOGY. 96(19).

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How RSV proteins join forces to overcome the host innate immune response

Tessa Van Royen, Iebe Rossey (UGent) , Koen Sedeyn (UGent) , Bert Schepens (UGent) and Xavier Saelens (UGent)

(2022) VIRUSES. 14(2).

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Protective efficacy of recombinant influenza hemagglutinin ectodomain fusions

Nidhi Mittal, Nayanika Sengupta, Sameer Kumar Malladi, Poorvi Reddy, Madhuraj Bhat, Raju S. Rajmani, Koen Sedeyn (UGent) , Xavier Saelens (UGent) , Somnath Dutta and Raghavan Varadarajan

(2021) VIRUSES-BASEL. 13(9).

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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models

Bert Schepens (UGent) , Loes van Schie (UGent) , Wim Nerinckx (UGent) , Kenny Roose (UGent) , Wander Van Breedam (UGent) , Daria Fijalkowska (UGent) , Simon Devos (UGent) , Wannes Weyts (UGent) , Sieglinde De Cae (UGent) , Sandrine Vanmarcke (UGent) , et al.

(2021) SCIENCE TRANSLATIONAL MEDICINE. 13(621).

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Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity

Fabien Henri Thery (UGent) , Lia Martina, Caroline Asselman (UGent) , Heidi Repo (UGent) , Y Zhang, Koen Sedeyn (UGent) , Georgios Moschonas (UGent) , C Bredow, QW Teo, J Zhang, et al.

(2021) NATURE COMMUNICATIONS. 12(1).

Academic Bibliography

dr. Koen Sedeyn

Immunogenicity and protection of octavalent influenza vaccine candidates using adjuvanted proteins or mRNA-LNPs in naïve mice

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base

Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline : caution is warranted

Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa

Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins

An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25

How RSV proteins join forces to overcome the host innate immune response

Protective efficacy of recombinant influenza hemagglutinin ectodomain fusions

An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity

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