prof. Jan De Waele
- ORCID iD
- 0000-0003-1017-9748
- Bio (via ORCID)
- Jan De Waele is a surgery-trained intensivist with a specific interest in infections in critically ill patients and works at the surgical ICU of the Ghent University Hospital in Belgium. Clinical interests include infections and abdominal catastrophes such as the abdominal compartment syndrome. His research activities currently focus on optimizing antibiotic therapy in severely ill infected patients to improve outcome and combat resistance development. He is active in several societies: he is currently chairing the Infection Section of the ESICM and president of the Belgian Society of Intensive Care Medicine.
Show
Sort by
-
Clinical outcomes in combination versus mono antibiotic therapy in ICU admitted patients with a suspected infection : a substudy of the DIANA study
-
Environmental sustainability and antimicrobials : an underestimated problem with far-reaching consequences
-
- Journal Article
- A2
- open access
Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection
-
Position paper on the reporting of norepinephrine formulations in critical care from the Society of Critical Care Medicine and European Society of Intensive Care Medicine Joint Task Force
-
The environmental impact of laboratory measurements in high-resource ICUs
-
Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children
-
- Journal Article
- A1
- open access
Optimized treatment of nosocomial peritonitis
-
Selective digestive decontamination-Pro
-
- Journal Article
- A1
- open access
The Sequential Organ Failure Assessment (SOFA) Score : has the time come for an update?
-
The spine intra-abdominal pressure (SIAP) trial : a prospective, observational, single arm, monocenter study looking at the evolutions of the IAP prior, during and after spine surgery
-
Tight blood-glucose control without early parenteral nutrition in the ICU
-
- Miscellaneous
- open access
Towards adequate and automated antibiotic dosing
-
- Journal Article
- A1
- open access
A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units : the SAFE-ICU study
-
Advancing precision-based antimicrobial dosing in critically ill patients
-
Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA) : an international prospective multicenter cohort study
-
Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients : the EUROBACT-2 international cohort study
-
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
-
- Journal Article
- A1
- open access
Ten golden rules for optimal antibiotic use in hospital settings : the WARNING call to action
-
- Journal Article
- A1
- open access
Early mobilisation in critically ill COVID-19 patients : a subanalysis of the ESICM-initiated UNITE-COVID observational study
-
- Journal Article
- A1
- open access
Ferroptosis and pyroptosis signatures in critical COVID-19 patients
-
- Journal Article
- A1
- open access
Generalizable calibrated machine learning models for real-time atrial fibrillation risk prediction in ICU patients
-
- Journal Article
- A1
- open access
Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients : a prospective single center observational study
-
- Journal Article
- A1
- open access
Potential of urine biomarkers CHI3L1, NGAL, TIMP-2, IGFBP7, and combinations as complementary diagnostic tools for acute kidney injury after pediatric cardiac surgery : a prospective cohort study
-
- Miscellaneous
- open access
Adequate antimicrobial dosing in critically ill patients receiving extracorporeal membrane oxygenation : where to go from here?
-
Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19 : a randomized clinical trial
-
- Journal Article
- A1
- open access
Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients : a descriptive analysis of the Eurobact II study
-
Intra-abdominal hypertension and abdominal compartment syndrome
-
- Journal Article
- A1
- open access
Use of broad-spectrum antimicrobials for more than 72 h and the detection of multidrug-resistant bacteria in Japanese intensive care units : a multicenter retrospective cohort study
-
- Journal Article
- A1
- open access
Fluid management, intra-abdominal hypertension and the abdominal compartment syndrome : a narrative review
-
Severe infections in the ICU : new perspectives and challenges
-
Source control in the management of sepsis and septic shock
-
- Journal Article
- A1
- open access
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis
-
Science communication for young researchers : a short guide to showcasing all your hard work
-
- Journal Article
- A1
- open access
Co-infection and ICU-acquired infection in COIVD-19 ICU patients : a secondary analysis of the UNITE-COVID data set
-
- Miscellaneous
- open access
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave : the global UNITE-COVID study (vol 48, pg 690, 2022)
-
- Journal Article
- A1
- open access
Development and evaluation of uncertainty quantifying machine learning models to predict piperacillin plasma concentrations in critically ill patients
-
- Journal Article
- A1
- open access
Why we may need higher doses of beta-lactam antibiotics : introducing the 'maximum tolerable dose'
-
Predictive value of the renal resistive index in the immediate postoperative period after kidney transplantation on short- and long-term graft and patient outcomes
-
Impact of mean perfusion pressure and vasoactive drugs on occurrence and reversal of cardiac surgery-associate acute kidney injury : a cohort study
-
- Journal Article
- A1
- open access
The role of abdominal drain cultures in managing abdominal infections
-
- Journal Article
- A1
- open access
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave : the global UNITE-COVID study
-
Variation in communication and family visiting policies in intensive care within and between countries during the Covid-19 pandemic : the COVISIT international survey
-
- Journal Article
- A1
- open access
Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis : an international cohort study
-
- Journal Article
- A1
- open access
Artificial intelligence in infection management in the ICU
-
Effects of cascade reporting of susceptibility profiles for Enterobacterales on broad-spectrum antibiotics use and resistance
-
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)
-
Comment on : 'Penetration of antibacterial agents into pulmonary epithelial lining fluid : an update'
-
An international survey of adherence to Surviving Sepsis Campaign Guidelines 2016 regarding fluid resuscitation and vasopressors in the initial management of septic shock
-
Infection control in the intensive care unit : expert consensus statements for SARS-CoV-2 using a Delphi method
-
Antibiotic dosing in sustained low-efficiency daily dialysis (SLEDD) : basic concepts and dosing strategies
-
Prediction of cardiac surgery associated-acute kidney injury (CSA-AKI) by healthcare professionals and urine cell cycle arrest AKI biomarkers [TIMP-2]*[IGFBP7] : a single center prospective study (the PREDICTAKI trial)
-
Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units : the PneumoINSPIRE study
-
Development and validation of a liquid chromatography high-resolution mass spectrometry orbitrap method for the sensitive quantification of amoxicillin, piperacillin, tazobactam and meropenem in human faeces
-
Surviving sepsis campaign : international guidelines for management of sepsis and septic shock 2021
-
Pilot study of oral fluid and plasma meropenem and piperacillin concentrations in the intensive care unit
-
Augmented renal clearance in critically ill COVID-19 patients : forewarned is forearmed
-
- Journal Article
- A1
- open access
Initial antimicrobial management of sepsis
-
- Journal Article
- A1
- open access
Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU : results from the international A- TEAMICU survey
-
- Journal Article
- A1
- open access
Antimicrobial stewardship in the ICU in COVID-19 times : the known unknowns
-
The future of antimicrobial dosing in the ICU : an opportunity for data science
-
- Journal Article
- A1
- open access
Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units
-
A three-day antimicrobial course for community-acquired pneumonia? Still no evidence in intensive care unit
-
- Journal Article
- A1
- open access
Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts
-
Pharmacokinetics and pharmacodynamics of ceftolozane/tazobactam in critically ill patients with augmented renal clearance
-
The gastrointestinal system in critical care : current insights and perspectives
-
Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 Era (PPE-SAFE) : an international survey (vol 59, pg 70, 2020)
-
Empiric cone-beam CT-guided embolization in acute lower gastrointestinal bleeding
-
Antimicrobial stewardship in ICUs during the COVID-19 pandemic : back to the 90s?
-
The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients : data from the Multinational Sampling Antibiotics in Renal Replacement Therapy study
-
Therapeutic drug monitoring of beta-lactam antibiotics in the ICU
-
Prolonged versus intermittent infusion of β-lactam antibiotics : a systematic review and meta-regression of bacterial killing in preclinical infection models
-
Systematic reviews and meta-analyses of interventions in the Journal of Critical Care
-
- Journal Article
- A1
- open access
Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak
-
- Journal Article
- A1
- open access
International variation in the management of severe COVID-19 patients
-
Antimicrobial therapeutic drug monitoring in critically ill adult patients : a Position Paper#
-
- Journal Article
- A1
- open access
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study
-
- Journal Article
- A1
- open access
Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 era (PPE-SAFE) : an international survey
-
- Journal Article
- A1
- open access
Antimicrobial de-escalation in the ICU : from recommendations to level of evidence
-
Corrigendum to 'Early target attainment of continuous infusionpiperacillin/tazobactam and meropenem in critically ill patients : a prospective observational study' [Journal of Critical Care 52(2019) 75–79]
-
Lung penetration, bronchopulmonary pharmacokinetic/pharmacodynamic profile and safety of 3 g of ceftolozane/tazobactam administered to ventilated, critically ill patients with pneumonia
-
- Journal Article
- A1
- open access
A clinician’s guide to management of intra-abdominal hypertension and abdominal compartment syndrome in critically ill patients
-
Prevalence and outcomes of infection among patients in intensive care units in 2017
-
Organising international research in critical care medicine : current challenges and potential solutions
-
Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care : no simple answers to simple questions - a viewpoint of experts
-
When not to start antibiotics : avoiding antibiotic overuse in the intensive care unit (vol 26, pg 35, 2020)
-
- Journal Article
- A1
- open access
European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria
-
Multidrug-resistant bacteria in ICU : fact or myth
-
Conventional amphotericin B must be avoided in Candida infections
-
Antimicrobial de-escalation in critically ill patients : a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)
-
A microbiologist consultant should attend daily ICU rounds
-
Improving care for the ICU patient with suspected infection : a multidisciplinary perspective
-
When not to start antibiotics : avoiding antibiotic overuse in the intensive care unit
-
Necrotizing skin and soft tissue infections in the intensive care unit
-
- Miscellaneous
- open access
How I search for a sepsis source
-
What happens after ICU discharge? : a within-hospital seamless care analysis of antimicrobial therapy
-
- Journal Article
- A1
- open access
Epidemiology of intra-abdominal infection and sepsis in critically ill patients : 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project
-
A practical approach to clinical antibiotic stewardship in the ICU patient with severe infection
-
Saturable elimination of piperacillin in critically ill patients : implications for continuous infusion
-
Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome : results of a repeat, international, cross-sectional survey
-
Optimal and responsible use of antibiotics
-
Subtherapeutic piperacillin concentrations in neurocritical patients
-
Clinical controversies in abdominal sepsis : insights for critical care settings
-
Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients : a prospective observational study
-
A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis : BLING III
-
ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients
-
- Journal Article
- A1
- open access
The significance of intra-abdominal pressure in neurosurgery and neurological diseases : a narrative review and a conceptual proposal
-
Measuring antibiotics in exhaled air in critically ill, non-ventilated patients : a feasibility and proof of concept study
-
Measuring unbound versus total piperacillin concentrations in plasma of critically ill patients : methodological issues and relevance
-
- Journal Article
- A1
- open access
Elaboration of consensus clinical endpoints to evaluate antimicrobial treatment efficacy in future hospital-acquired/ventilator-associated bacterial pneumonia clinical trials
-
Antibiotic stewardship in sepsis management : toward a balanced use of antibiotics for the severely ill patient
-
Rationalizing antimicrobial therapy in the ICU : a narrative review
-
Personalized antibiotic dosing for the critically ill
-
Persistence of piperacillin concentrations after treatment discontinuation : in cauda venenum?
-
Isavuconazole versus caspofungin in the treatment of candidemia and other invasive Candida infections : the ACTIVE Trial
-
- Journal Article
- A1
- open access
Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units : protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project
-
Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem : a comparison of eight pharmacokinetic models
-
- Conference Paper
- C3
- open access
Quantitation of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)
-
Optimal duration of antibiotic treatment in Gram-negative infections
-
Target attainment of empirically dosed continuous infusion of piperacillin/tazobactam and meropenem in critically ill patients
-
Continuous infusion piperacillin in critically ill patients : predicting concentrations using published population pharmacokinetic models
-
Impact of AST meetings on antimicrobial therapy decisions in the ICU
-
Emergence of antimicrobial resistance to piperacillin/tazobactam or meropenem in the ICU : intermittent versus continuous infusion : a retrospective cohort study
-
- Journal Article
- A1
- open access
A complete and multifaceted overview of antibiotic use and infection diagnosis in the intensive care unit : results from a prospective four-year registration
-
- Journal Article
- A1
- open access
Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
-
Antimicrobial resistance and antibiotic stewardship programs in the ICU : insistence and persistence in the fight against resistance : a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance
-
- Journal Article
- A2
- open access
What every intensivist should know about the management of peritonitis in the intensive care unit
-
- Journal Article
- A1
- open access
Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome : a systematic review and meta-analysis
-
- Journal Article
- A1
- open access
Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients : a double-blind randomized trial
-
Generic and optimized antibacterial dosing strategies in the critically ill
-
Prolonged infusion of beta-lactam antibiotics in critically ill patients : revisiting the evidence
-
Population pharmacokinetics of continuous infusion meropenem in critically ill patients : a comparison of eight approaches
-
Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients
-
- Conference Paper
- C3
- open access
Dosing of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)
-
Higher fluid balance increases the risk of death from sepsis : results from a large international audit
-
Implementing antimicrobial stewardship in critical care : a practical guide
-
Antimicrobial stewardship in ICU
-
Impact and management of abdominal compartment syndrome in patients with abdominal sepsis
-
Population pharmacokinetics of continuous infusion piperacillin in critically ill patients
-
- Journal Article
- A1
- open access
Proceedings of resources for optimal care of acute care and emergency surgery consensus summit Donegal Ireland
-
- Miscellaneous
- open access
Update from the Abdominal Compartment Society (WSACS) on intra-abdominal hypertension and abdominal compartment syndrome : past, present, and future beyond Banff 2017
-
The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections
-
- Journal Article
- A1
- open access
Early enteral nutrition in critically ill patients : ESICM clinical practice guidelines
-
- Journal Article
- A1
- open access
Management of intra-abdominal infections : recommendations by the WSES 2016 consensus conference
-
- Journal Article
- A1
- open access
The Global Alliance for Infections in Surgery : defining a model for antimicrobial stewardship : results from an international cross-sectional survey
-
To which extent can we decrease antibiotic duration in critically ill patients?
-
Stability of amoxicillin and amoxicillin/clavulanic acid reconstituted in isotonic saline
-
Diagnostic strategy and timing of intervention in infected necrotizing pancreatitis : an international expert survey and case vignette study
-
Reducing antibiotic use in the ICU : a time-based approach to rational antimicrobial use
-
Intra-abdominal hypertension and the abdominal compartment syndrome
-
A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the intensive care unit
-
- Journal Article
- A1
- open access
Antimicrobials : a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
-
Amended classification of the open abdomen
-
Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? : an observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort
-
What about confidence intervals? : a word of caution when interpreting PTA simulations
-
Abdominal sepsis
-
- Journal Article
- A1
- open access
Long-term outcome in ICU patients with acute kidney injury treated with renal replacement therapy : a prospective cohort study
-
Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients : a retrospective observational study
-
Therapeutic management of peritonitis : a comprehensive guide for intensivists
-
Permissive intraabdominal hypertension following complex abdominal wall reconstruction
-
Intermittent axillary temperature measurement fails to detect fever in critically ill patients
-
- Journal Article
- A1
- open access
Decompressive laparotomy for abdominal compartment syndrome
-
Understanding antibiotic stewardship for the critically ill
-
Understanding abdominal compartment syndrome
-
- Journal Article
- A2
- open access
Identification of quality indicators for the nutritional management of adult hospitalized patients by a modified Delphi process
-
WSACS : the Abdominal Compartment Society : a Society dedicated to the study of the physiology and pathophysiology of the abdominal compartment and its interactions with all organ systems
-
Being overweight is associated with greater survival in ICU patients : results from the Intensive Care Over Nations audit
-
Open abdomen management : challenges and solutions for the ICU team
-
- Journal Article
- A2
- open access
Methodological background and strategy for the 2012−2013 updated consensus definitions and clinical practice guidelines from the abdominal compartment society
-
Targeted temperature management and neuroprognostication after cardiac arrest: a survey in Belgium
-
- Journal Article
- A2
- open access
Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma
-
- Journal Article
- A2
- open access
A user's guide to intra-abdominal pressure measurement
-
- Journal Article
- A2
- open access
How to deal with an open abdomen?
-
- Journal Article
- A2
- open access
What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension
-
- Journal Article
- A2
- open access
Management of abdominal sepsis: a paradigm shift?
-
- Journal Article
- A1
- open access
Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients : data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients study
-
Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria
-
- Miscellaneous
- open access
The abdominal compartment syndrome : evolving concepts and future directions
-
- Journal Article
- A2
- open access
Intra-abdominal hypertension and abdominal compartment syndrome in burns, obesity, pregnancy, and general medicine
-
Task force on management and prevention of Acinetobacter baumannii infections in the ICU
-
Epidemiology of augmented renal clearance in mixed ICU patients
-
The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs
-
- Journal Article
- A1
- open access
Randomized Trial of Micafungin for the Prevention of Invasive Fungal Infection in High-Risk Liver Transplant Recipients
-
- Journal Article
- A2
- open access
Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome: results of an international survey
-
Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review
-
A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients
-
Augmented renal clearance and therapeutic monitoring of β-lactams
-
Subtleties in practical application of prolonged infusion of β-lactam antibiotics
-
Comparison of different equations to assess glomerular filtration in critically ill patients
-
Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS
-
Exploration of the pre-analytical stability of β-lactam antibiotics in plasma and blood: implications for therapeutic drug monitoring and pharmacokinetic studies
-
Stability of generic brands of meropenem reconstituted in isotonic saline
-
Measuring unbound versus total vancomycin concentrations in serum and plasma: methodological issues and relevance
-
- Journal Article
- A2
- open access
The role of abdominal compliance, the neglected parameter in critically ill patients : a consensus review of 16. Part 2 : measurement techniques and management recommendations
-
- Journal Article
- A2
- open access
The role of abdominal compliance, the neglected parameter in critically ill patients : a consensus review of 16. Part 1 : definitions and pathophysiology
-
Clasificación internacional y multidisciplinaria de la pancreatitis aguda : edición española 2013
-
Assessment of the worldwide burden of critical illness : the Intensive Care Over Nations (ICON) audit
-
Impact of infection on the prognosis of critically ill cirrhotic patients: results from a large worldwide study.
-
- Journal Article
- A2
- open access
The use of bio-electrical impedance analysis (BIA) to guide fluid management, resuscitation and deresuscitation in critically ill patients : a bench-to-bedside review
-
- Journal Article
- A2
- open access
How to treat infections in a surgical intensive care unit
-
- Journal Article
- A1
- open access
Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit : a retrospective analysis
-
Protein binding of vancomycin: the impact of temperature on free plasma concentrations
-
Impact of de-escalation on ICU patients' prognosis
-
Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients
-
- Journal Article
- A1
- open access
Infections and use of antibiotics in patients admitted for severe acute pancreatitis : data from the EPIC II study
-
- Journal Article
- A1
- open access
Efficacy and safety of moxifloxacin in hospitalized patients with secondary peritonitis : pooled analysis of four randomized phase III trials
-
What is new in the use of aminoglycosides in critically ill patients?
-
Beta-lactam antibiotic dosing during continuous renal replacement therapy: how can we optimize therapy?
-
Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures
-
Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis
-
High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial
-
Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy
-
- Journal Article
- A1
- open access
Abdominal infections in the intensive care unit : characteristics, treatment and determinants of outcome
-
High versus low blood-pressure target in septic shock
-
Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: lessons from the DALI study
-
An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units
-
DALI: Defining Antibiotic Levels in Intensive care unit patients: are current beta-lactam antibiotic doses sufficient for critically ill patients?
-
Acute pancreatitis
-
- Miscellaneous
- open access
Is intra-abdominal hypertension a missing factor that drives multiple organ dysfunction syndrome?
-
Does consistent piperacillin dosing result in consistent therapeutic concentrations in critically ill patients?: a longitudinal study over an entire antibiotic course
-
Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial
-
- Journal Article
- A1
- open access
Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients?: data from the multinational DALI study
-
Efficacy of micafungin in invasive candidiasis caused by common Candida species with special emphasis on non-albicans Candida species
-
Aminoglycosides for life-threatening infections: a plea for an individualized approach using intensive therapeutic drug monitoring
-
- Journal Article
- A1
- open access
Moxifloxacin dosing in post-bariatric surgery patients
-
'Piece' of mind: end of life in the intensive care unit: statement of the Belgian Society of Intensive Care Medicine
-
- Journal Article
- A1
- open access
IAP/APA evidence-based guidelines for the management of acute pancreatitis
-
- Journal Article
- A1
- open access
Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome : a prospective multicentre study
-
Einteilung des Schweregrads der akuten Pankreatitis : internationale, multidisziplinäre klinische Klassifikation auf Basis pathogenetischer Determinanten : Deutsche Version 2013
-
Consensus strategies for the nonoperative management of patients with blunt splenic injury : a Delphi study
-
- Book Chapter
- open access
Optimizing β-lactam antibiotic therapy in the critically ill : moving towards patient-tailored antibiotic therapy
-
Intra-abdominal hypertension : definitions, monitoring, interpretation and management
-
- Journal Article
- A1
- open access
Diagnosis and management of temperature abnormality in ICUs : a EUROBACT investigators' survey
-
Pancreatic stone protein for predicting outcome in peritonitis : limitations and challenges
-
Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients
-
Augmented renal clearance is a common finding with worse clinical outcome in critically ill patients receiving antimicrobial therapy
-
A survey of beta-lactam antibiotics and vancomycin dosing strategies in intensive care units and general wards in Belgian hospitals.
-
Factors associated with inadequate early vancomycin levels in critically ill patients treated with continuous infusion
-
- Journal Article
- A1
- open access
Intra-abdominal hypertension and the abdominal compartment syndrome : updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome
-
- Miscellaneous
- open access
Identifying patients at risk for augmented renal clearance in the ICU : limitations and challenges
-
- Journal Article
- A1
- open access
Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?
-
Randomised clinical trial of moxifloxacin versus ertapenem in complicated intra-abdominal infections: results of the PROMISE study
-
TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial
-
Renal physiology in the critically ill obese patient
-
Prospektive, randomisierte, double-dummy, doppelblinde, multizentrische Studie zum Vergleich der Sicherheit und Wirksamkeit von Moxifloxacin i.v. mit Ertapenem i.v. bei Patienten mit komplizierten intraabdominellen Infektionen: Ergebnisse der PROMISE-Studie
-
Epidemiology of contrast-associated acute kidney injury in ICU patients: reply to Valette and du Cheyron
-
Management of necrotizing skin and soft tissue infections
-
- Journal Article
- A1
- open access
DALI : Defining Antibiotic Levels in Intensive care unit patients : a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic
-
Determinant-based classification of acute pancreatitis severity : an international multidisciplinary consultation
-
Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method
-
What's behind the failure of emerging antibiotics in the critically ill?: understanding the impact of altered pharmacokinetics and augmented renal clearance