prof. Jan De Waele

ORCID iD: 0000-0003-1017-9748
Bio (via ORCID): Jan De Waele is a surgery-trained intensivist with a specific interest in infections in critically ill patients and works at the surgical ICU of the Ghent University Hospital in Belgium. Clinical interests include infections and abdominal catastrophes such as the abdominal compartment syndrome. His research activities currently focus on optimizing antibiotic therapy in severely ill infected patients to improve outcome and combat resistance development. He is active in several societies: he is currently chairing the Infection Section of the ESICM and president of the Belgian Society of Intensive Care Medicine.

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- Journal Article
- A1
- open access
Towards trustful machine learning for antimicrobial therapy using an explainable artificial intelligence dashboard

Thomas De Corte (UGent) , Jarne Verhaeghe (UGent) , Femke Ongenae (UGent) , Jan De Waele (UGent) and Sofie Van Hoecke (UGent)

(2025) APPLIED SCIENCES-BASEL. 15(20).
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The impact of intensive care strain on patients' outcomes : a multinational observational cohort (UNITE-COVID) study

Katharina Kohler, Thomas De Corte (UGent) , Massimiliano Greco, Pedro Povoa, Maurizio Cecconi, Marlies Ostermann, Jan De Waele (UGent) , Andrew Conway Morris, Jolien Van Hecke (UGent) and [missing] UNITE-COVID Investigators

(2025) CRITICAL CARE. 29(1).
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Evaluating early mobilisation in critically ill COVID-19 patients : secondary analysis from the ESICM UNITE-COVID-II multicentre observational study

Maximilian Markus, Maximilian Lindholz, Nils Daum, Anne Pohrt, Elie Azoulay, Maurizio Cecconi, Giuseppe Citerio, Thomas De Corte (UGent) , Frantisek Duska, Laura Galarza, et al.

(2025) ANAESTHESIA CRITICAL CARE & PAIN MEDICINE. 44(4).
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Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

Louise Nuyttens (UGent) , Marah Heyerick (UGent) , Geike Heremans (UGent) , Elise Moens (UGent) , Maxime Roes (UGent) , Céline Van Dender (UGent) , Liesbet De Bus (UGent) , Johan Decruyenaere (UGent) , Jan De Waele (UGent) , Jolien Vandewalle (UGent) , et al.

(2025) CELL REPORTS. 44(8).
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A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations : from premature infants to the elderly

Daming Kong, Jason A. Roberts, Jeffrey Lipman, Fabio Silvio Taccone, Michael Cohen-Wolkowiez, Fekade B. Sime, Danny Tsai, Pieter De Cock (UGent) , Sutep Jaruratanasirikul, Sofie A. M. Dhaese, et al.

(2025) CLINICAL PHARMACOKINETICS. 64(1). p.107-126
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Management of adult sepsis in resource-limited settings : global expert consensus statements using a Delphi method

Louise Thwaites, Prashant Nasa, Brett Abbenbroek, Vu Quoc Dat, Simon Finfer, Arthur Kwizera, Lowell Ling, Suzana M. Lobo, Robert Sinto, Dita Aditianingsih, et al.

(2025) INTENSIVE CARE MEDICINE. 51(1). p.21-38
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- Miscellaneous
Does artificial intelligence close gaps in clinical pharmacology in the ICU?

Matthias Gijsen and Jan De Waele (UGent)

(2025) INTENSIVE CARE MEDICINE. 51(2). p.385-388
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Preferences and attitudes on acetate- versus lactate-buffered crystalloid solutions for intravenous fluid therapy : an international survey

Karen Louise Ellekjaer, Praleene Sivapalan, Sheila N. Myatra, Lasse Gronningsaeter, Johanna Hastbacka, Paul J. Young, Andrew J. Boyle, Marlies Ostermann, Carmen A. Pfortmueller, Ieva Jovaisiene, et al.

(2025) ACTA ANAESTHESIOLOGICA SCANDINAVICA. 69(1).
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Preferences for albumin use in adult intensive care unit patients with shock : an international survey (vol 68, pg 1234, 2024)

P. Sivapalan, K. L. Ellekjaer, A. Perner, Morten Hylander Møller, Anders Granholm, Lasse Grønningsæter, Marlies Ostermann, Rob Mac Sweeney, Maria Cronhjort, Johanna Hästbacka, et al.

(2025) ACTA ANAESTHESIOLOGICA SCANDINAVICA. 69(1).
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Impact of reporting rapid susceptibility results in Gram negative bloodstream infections : a real world prospective study

Anne-Sophie Messiaen (UGent) , Stien Vandendriessche (UGent) , Emilie De Muynck, Gregory Strubbe (UGent) , Liesbet De Bus (UGent) , Petra Schelstraete (UGent) , Kristen Decommer, Sanne De Smet (UGent) , Alexander Soetens (UGent) , Leslie Naesens (UGent) , et al.

(2025) EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 44(4). p.847-853

Academic Bibliography

prof. Jan De Waele

Towards trustful machine learning for antimicrobial therapy using an explainable artificial intelligence dashboard

The impact of intensive care strain on patients' outcomes : a multinational observational cohort (UNITE-COVID) study

Evaluating early mobilisation in critically ill COVID-19 patients : secondary analysis from the ESICM UNITE-COVID-II multicentre observational study

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations : from premature infants to the elderly

Management of adult sepsis in resource-limited settings : global expert consensus statements using a Delphi method

Does artificial intelligence close gaps in clinical pharmacology in the ICU?

Preferences and attitudes on acetate- versus lactate-buffered crystalloid solutions for intravenous fluid therapy : an international survey

Preferences for albumin use in adult intensive care unit patients with shock : an international survey (vol 68, pg 1234, 2024)

Impact of reporting rapid susceptibility results in Gram negative bloodstream infections : a real world prospective study

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