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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function
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- Journal Article
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Mousepost 2.0, a major expansion of the resource
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- Journal Article
- A1
- open access
Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock
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- Journal Article
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Coding variants in mouse and rat model organisms : mousepost and ratpost
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- Journal Article
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Dimerization of the glucocorticoid receptor and its importance in (patho)physiology : a primer
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- Journal Article
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Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding
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Reprogramming of glucocorticoid receptor function by hypoxia
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Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis
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- Journal Article
- A1
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ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation
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Ratpost : a searchable database of protein-inactivating sequence variations in 40 sequenced rat-inbred strains
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- Journal Article
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Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium
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Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system
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- Journal Article
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Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis
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- Journal Article
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A general introduction to glucocorticoid biology
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TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
(2019) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 116(26). p.12942-12951 -
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J
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Identifying and classifying protein coding gene polymorphisms between laboratory mouse strains and investigating glucocorticoid actions in sepsis models
(2018) -
Easy access to and applications of the sequences of all protein-coding genes of all sequenced mouse strains
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Using the inbred mouse strain SPRET/EiJ to provide novel insights in inflammation and infection research
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- Journal Article
- A1
- open access
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
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- Miscellaneous
- open access
Learning lessons in sepsis from the children
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Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains
(2017) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 114(34). p.9158-9163 -
- Journal Article
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- open access
The nature of the GRE influences the screening for GR-activity enhancing modulators
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Efficient analysis of mouse genome sequences reveal many nonsense variants
(2016) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113(20). p.5670-5675 -
- Journal Article
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Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1
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DUSP3 genetic deletion confers M2-like macrophage-dependent tolerance to septic shock
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Determining differentially expressed miRNAs and validating miRNA-target relationships using the SPRET/Ei mouse strain