prof. dr. Lars Vereecke
- ORCID iD
- 0000-0002-1593-862X
- Bio (via ORCID)
- My research lab is focusing on host-microbiota interactions in health and disease, using unique transgenic mouse models of human pathologies (IBD, arthritis, colorectal cancer). My research lab (host-microbiota interaction lab - HMI) is coördinating the germ-free and gnotobiotic mouse facility at Ghent University. I am teamleader at the VIB Center for Inflammation Research (IRC) and assistant professor at Ghent University.
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Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow's milk allergy
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- Journal Article
- A1
- open access
The autoinflammation-associated NLRC4<SUP>V341A</SUP> mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice
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- Journal Article
- A1
- open access
Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1
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GDF15 mediates inflammation-associated bone loss through a brain-bone axis
(2023) -
- Journal Article
- A1
- open access
Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology
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- Journal Article
- A1
- open access
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
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- Conference Paper
- C3
- open access
Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy
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- Journal Article
- A1
- open access
Sterile triggers drive joint inflammation in TNF‐ and IL-1β‐dependent mouse arthritis models
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Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy
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- Journal Article
- A1
- open access
Hepatic glutamine synthetase controls N-5-methylglutamine in homeostasis and cancer
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Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy
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Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy
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Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow’s milk allergy
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Towards a mouse model for studying food allergies from a metabolomics perspective : the case of pediatric cow’s milk allergy
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Novel lipidomic biomarker panel towards improving of diagnostic accuracy in pediatric cow's milk allergy
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- Journal Article
- A1
- open access
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia
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- Journal Article
- A1
- open access
ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation
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- Journal Article
- A1
- open access
The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice : a new factor in the host-microbiome interaction
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- Journal Article
- A1
- open access
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
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- Conference Paper
- C3
- open access
Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy
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- Journal Article
- A1
- open access
Microbes exploit death-induced nutrient release by gut epithelial cells
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- Journal Article
- A1
- open access
Therapeutic depletion of CCR8(+) tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
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- Journal Article
- A1
- open access
Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients
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Targeting neutrophils in asthma : a therapeutic opportunity?
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Revisiting the gut-joint axis : links between gut inflammation and spondyloarthritis
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Zeb2 drives invasive and microbiota-dependent colon carcinoma
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Publisher correction : Zeb2 drives invasive and microbiota-dependent colon carcinoma
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Risks and benefits of corticosteroids in arthritic diseases in the clinic
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The anti-inflammatory protein TNFAIP3/A20 binds the WD40 domain of ATG16L1 to control the autophagic response, NFKB/NF-κB activation and intestinal homeostasis
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A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
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- Journal Article
- A1
- open access
Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis
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The role of the microbiome in gut and joint inflammation in psoriatic arthritis and spondyloarthritis
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Tumour necrosis factor : out of my heart!
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Ruminococcus on the horizon in arthritic disease
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Cellular functions of optineurin in health and disease
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- Journal Article
- A1
- open access
A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death
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The prosurvival IKK-related kinase IKKε integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine
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Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling
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- Journal Article
- A1
- open access
A20 deficiency in lung epithelial cells protects against influenza A virus infection
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M-CSF and GM-CSF receptor signaling differentially regulate monocyte maturation and macrophage polarization in the tumor microenvironment
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- Journal Article
- A1
- open access
Structural and adhesive properties of the long polar fimbriae protein LpfD from adherent-invasive Escherichia coli
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A20 controls intestinal homeostasis through cell-specific activities
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RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
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A20 in inflammation and autoimmunity
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Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
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A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis
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Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
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Enterocyte death and intestinal barrier maintenance in homeostasis and disease
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A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
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- Journal Article
- A1
- open access
Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimrnune disease
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Controlling inflammation and cell death at the intestinal epithelial interface and beyond: lessons from conditional A20 knockout mice
(2011) -
Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis
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The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
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Prolonged exposure to IL-1 beta and IFN gamma induces necrosis of L929 tumor cells via a p38MAPK/NF-kappa B/NO-dependent mechanism
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Identification and evaluation of protein-protein interactions involved in NF-kB signaling using MAPPIT technology