prof. ir. Bruno De Geest

Journal Article
A2
open access

A one-step workflow for size-based separation of extracellular vesicles with integrated surface marker detection

Lien Lippens (UGent) , Niké Guilbert (UGent) , Sofie Van Dorpe (UGent) , Sarah Deville (UGent) , Robin Boiy (UGent) , Quentin Roux, Nicolaas Lumen (UGent) , Ilkka Miinalainen, Pekka Rappu, Katrien Vandecasteele (UGent) , et al.

(2026) JOURNAL OF EXTRACELLULAR BIOLOGY. 5(3).

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Multivalent antibody-recruiting molecules for targeted immune-killing of carbonic anhydrase IX-expressing cancer cells

Haixia Peng, Jamie De Baere (UGent) , Federica Cappellesso, Kieran English (UGent) , Kim Deswarte (UGent) , Damya Laoui, Bart Lambrecht (UGent) , Bruno De Geest (UGent) and Benoit Louage (UGent)

(2026) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.

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pH-triggered cell surface anti-hapten antibody recruitment by amphiphilic block copolymers containing ionizable amines and haptens in the hydrophobic block

Haixia Peng, Benoit Louage (UGent) , Jamie De Baere (UGent) , Lutz Nuhn (UGent) and Bruno De Geest (UGent)

(2026) MACROMOLECULAR RAPID COMMUNICATIONS.

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Multivalent antibody-recruiters targeting fibroblast activation protein for innate immune killing

Weiwei Mu (UGent) , Yong Chen (UGent) , Zifu Zhong (UGent) , Jamie De Baere (UGent) , Heleen Lauwers (UGent) , Demi Defreyne (UGent) , Haixia Peng, Bruno De Geest (UGent) and Benoit Louage (UGent)

(2026) BIOMACROMOLECULES. 27(6). p.4026-4037

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Journal Article
A1
open access

Dual lipid modulation overcomes ferroptosis resistance in high-risk neuroblastoma

Ine Koeken, Magali Walravens, Roberto Fernández-Acosta, Ruben Van Hoyweghen, Iuliana Vintea (UGent) , Yingyi Kong, Bianka Golba, Jonas Dehairs, Ali Talebi, Johannes V. Swinnen, et al.

(2026) CELL DEATH AND DIFFERENTIATION. 33(5). p.903-913

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Journal Article
A1
open access

Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye

Weiran Li (UGent) , Helena Vanluchene, Laura Raes, Karen Peynshaert (UGent) , Liene Veys, Sofía González Hernández (UGent) , Emily De Lombaerde, Bruno De Geest (UGent) , Niek Sanders (UGent) , Lieve Moons, et al.

(2025) JOURNAL OF CONTROLLED RELEASE. 385.

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Journal Article
A1
open access

Poly(2-hydroxymethyl-2-oxazoline) as super-hydrophilic antifouling polymer

Somdeb Jana (UGent) , Milan Roels, Meike Leiske (UGent) , Yann Bernhard (UGent) , Bruno De Geest (UGent) , Kristof Van Hecke (UGent) and Richard Hoogenboom (UGent)

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(12).

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Cyclic poly(2-methyl-2-oxazoline)-lipid conjugates are good alternatives to poly(ethylene glycol)-lipids for lipid nanoparticle mRNA formulation

Bianka Golba, Zifu Zhong (UGent) , Matteo Romio, Ruben Almey (UGent) , Dieter Deforce (UGent) , Maarten Dhaenens (UGent) , Niek Sanders (UGent) , Edmondo M. Benetti and Bruno De Geest (UGent)

(2025) BIOMACROMOLECULES. 26(3). p.1816-1825

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Admixing of mRNA with pre‐formed lipid nanoparticles containing a slightly‐cationic ionizable lipid allows for efficient mRNA transfection in vitro and in vivo

Haixiu Wang, Heleen Lauwers (UGent) , Mark Gontsarik (UGent) , Yong Chen (UGent) , Niek Sanders (UGent) , Miffy Hok Yan Cheng, Bruno De Geest (UGent) and Zifu Zhong (UGent)

(2025) ADVANCED HEALTHCARE MATERIALS. 14(23).

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Journal Article
A1
open access

Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways

Sofie Rennen (UGent) , Victor Bosteels, Clint De Nolf (UGent) , Sandra Maréchal (UGent) , Jessica Vetters (UGent) , Karo Van Lil (UGent) , Greta Webb (UGent) , Janne Swinnen (UGent) , Evelien Van De Velde (UGent) , Farzaneh Fayazpour (UGent) , et al.

(2025) CELL REPORTS. 44(8).

Academic Bibliography

prof. ir. Bruno De Geest

A one-step workflow for size-based separation of extracellular vesicles with integrated surface marker detection

Multivalent antibody-recruiting molecules for targeted immune-killing of carbonic anhydrase IX-expressing cancer cells

pH-triggered cell surface anti-hapten antibody recruitment by amphiphilic block copolymers containing ionizable amines and haptens in the hydrophobic block

Multivalent antibody-recruiters targeting fibroblast activation protein for innate immune killing

Dual lipid modulation overcomes ferroptosis resistance in high-risk neuroblastoma

Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye

Poly(2-hydroxymethyl-2-oxazoline) as super-hydrophilic antifouling polymer

Cyclic poly(2-methyl-2-oxazoline)-lipid conjugates are good alternatives to poly(ethylene glycol)-lipids for lipid nanoparticle mRNA formulation

Admixing of mRNA with pre‐formed lipid nanoparticles containing a slightly‐cationic ionizable lipid allows for efficient mRNA transfection in vitro and in vivo

Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways

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