Lieselotte Vande Walle
work address
Albert Baertsoenkaai 3
9000 Gent
9000 Gent
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- 2014
- Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
- Airway structural cells regulate TLR5-mediated mucosal adjuvant activity
- Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
- FADD and Caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes
- The small GTPase Arf6 is essential for the Tram/Trif pathway in RLR4 signaling
- 2012
- Defective Dock2 expression in a subset of ASC-deficient mouse lines
- Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens
- 2011
- The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization
- Non-canonical inflammasome activation targets caspase-11
- Deregulated inflammasome signaling in disease