prof. dr. Thomas De Beer
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T-shaped partial least squares for high-dosed new active pharmaceutical ingredients in continuous twin-screw wet granulation : granule size prediction with limited material information
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Validation of model-based design of experiments for continuous wet granulation and drying
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A colourful way to unravel the important fluidization-related granule size effect on semi-continuous drying
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Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics
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An in silico framework for the robust tuning of an MPC for a continuous blender in a production line for pharmaceutical oral solid dosages.
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- Journal Article
- A1
- open access
Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids
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- Conference Paper
- C3
- open access
Two-dimensional granule property measurement using hyperspectral imaging in continuous pharmaceutical wet granulation
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Impact of alternative lubricants on process and tablet quality for direct compression
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- Journal Article
- A1
- open access
Continuous direct compression: development of an empirical predictive model and challenges regarding PAT implementation
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- Journal Article
- A1
- open access
The effect of binder types on the breakage and drying behavior of granules in a semi-continuous fluid bed dryer after twin screw wet granulation