- ORCID iD
- 0000-0003-1989-1336
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Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
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- Conference Paper
- C3
- open access
Dramatic impact of blood collection tube and RNA purification method on extracellular RNA transcriptomes
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- Conference Paper
- C3
- open access
Exploration of neuroblastoma xenograft models for the analysis of tumoral cell-free RNA in murine blood plasma
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- Journal Article
- A2
- open access
Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma
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Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA
(2023) -
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
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- Journal Article
- A2
- open access
Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation
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Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma
(2022) -
The Extracellular RNA Quality Control (exRNAQC) study (phase 2)
(2022) -
The Extracellular RNA Quality Control (exRNAQC) study (phase 1)
(2022) -
Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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- Miscellaneous
- open access
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
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- Journal Article
- A1
- open access
Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA
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- Journal Article
- A2
- open access
Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA
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Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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- Journal Article
- A1
- open access
A G316A polymorphism in the ornithine decarboxylase gene promoter modulates MYCN-driven childhood neuroblastoma
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Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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Whole transcriptome profiling of liquid biopsies from patient-derived xenograft (PDX) models
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- Journal Article
- A1
- open access
A recurrent and transesophageal echocardiography-associated outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae complex in cardiac surgery patients
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- Journal Article
- A1
- open access
Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR
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Nosocomial outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae among cardiothoracic surgical patients : causes and consequences
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ALK positively regulates MYCN activity through repression of HBP1 expression
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Circulating microRNA biomarkers for metastatic neuroblastoma
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Longitudinal evaluation of murine serum microRNAs as biomarkers for neuroblastoma burden and therapeutic TP53 reactivation
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The ornithine decarboxylase G316A promoter polymorphism impacts neuroblastoma clinical outcome and may identify patients particularly susceptible to polyamine inhibition
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Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
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Performance of the preanalytical check module of the Stago STA R Max2 mechanical endpoint detection analyzer for assessing the impact of hemolysis, lipemia, and icterus on aPTT and PT
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Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium
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Pharmacological restoration of tumour suppressor protein p53 in neuroblastoma : seeking synergy and non-invasive biomarkers
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Analytical and pre-analytical performance characteristics of a novel cartridge-type blood gas analyzer for point-of-care and laboratory testing
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Meticulous plasma isolation is essential to avoid false low-level viraemia in Roche Cobas HIV-1 viral load assays
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Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2 allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11
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Accelerating drug development for neuroblastoma - New drug development strategy : an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma project
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Identifying familial hypercholesterolemia in pediatric and adult patients : is screening relevant in a tertiary care setting?
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Analytical and diagnostic performance evaluation of the new Sysmex UF-5000 for automated urine sediment analysis
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The HBP1 tumor suppressor is a negative epigenetic regulator of MYCN driven neuroblastoma through interaction with the PRC2 complex
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MicroRNA expression analysis using small RNA sequencing discovery and RT-qPCR-based validation
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The HBP1 tumour suppressor is a negative epigenetic regulator of MYCN-driven neuroblastoma through interaction with the PRC2 complex
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HBP1 is a negative epigenetic regulator of MYCN-driven neuroblastoma through interaction with the PRC2 complex
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- Journal Article
- A1
- open access
Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma
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Hepatitis E virus serology and PCR : does the methodology matter?
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A negative lactate dehydrogenase activity corrected after sample neuraminidase treatment
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- Journal Article
- A1
- open access
Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay
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Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis
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Evaluation of the role of germline RECQL variants in Belgian patients referred for genetic testing in the context of familial breast/ovarian cancer
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The HBP1 tumor suppressor is a negative epigenetic regulator of MYCN driven neuroblastoma through interaction with the PRC2 complex
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The HBP1 tumor suppressor is a negative epigenetic regulator of MYCN driven neuroblastoma through interaction with the PRC2 complex
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The HBP1 tumor suppressor is an epigenetic regulator of MYCN driven neuroblastoma through interaction with the PRC2 complex
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- Journal Article
- A1
- open access
Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples
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Identification of non-invasive biomarkers for treatment response in neuroblastoma by circulating miRNA profiling
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An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers
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- Journal Article
- A1
- open access
Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation
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- Journal Article
- A1
- open access
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
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BRCA2 polymorphic stop codon K3326X and the risk of breast, prostate, and ovarian cancers
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Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment
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Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment
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Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment
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The HBP1 tumour suppressor at multiple regulatory cross roads in neuroblastoma
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- Miscellaneous
- open access
Oncogenetic testing, diagnosis and follow-up in Birt-Hogg-Dubé syndrome, familial atypical multiple mole melanoma syndrome and neurofibromatosis 1 and 2
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- Miscellaneous
- open access
Oncogenetic testing and follow-up for women with familial breast/ovarian cancer, Li-Fraumeni syndrome and Cowden syndrome
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- Miscellaneous
- open access
Oncogenetic testing for persons with hereditary endocrine cancer syndromes
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HBP1 downregulation through mutant ALK represents a novel mechanism for cooperative MYCN activation in neuroblastoma
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Hepatitis E virus serology and PCR : does the methodology matter?
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The G2 micronucleus-assay for the analysis of in vitro chromosomal radiosensitivity in individuals carrying a BRCA1 mutation
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BRCA1, BRCA2 and PALB2 mutations and CHEK2 c. 1100delC in different South African ethnic groups diagnosed with premenopausal and/or triple negative breast cancer
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- Journal Article
- A1
- open access
Identification of miRNAs contributing to neuroblastoma chemoresistance
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- Journal Article
- A1
- open access
Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma
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- Journal Article
- A1
- open access
Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors
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- Journal Article
- A1
- open access
Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma
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Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers
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- Journal Article
- A1
- open access
Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers
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Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment
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Synergistic combined molecular treatment targeting the HBP1 tumor suppressor gene in neuroblastoma
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CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
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CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
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Targeted analysis of TP53 pathway SNPs in neuroblastoma patients
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Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
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Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
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The G2 micronucleus assay for the analysis of in vitro chromosomal radiosensitivity in individuals carrying a BRCA1 or BRCA2 mutation
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Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
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Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
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The G2-micronucleus assay for the detection of in vitro chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers
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Clinical burden of hepatitis E infections in Belgium
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- Journal Article
- A1
- open access
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers
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Characterization of ALK driven molecular networks identifies perturbed RET and cholinergic signaling in neuroblastoma
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- Journal Article
- A1
- open access
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
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Genetisch geïnspireerde toekomstperspectieven voor de therapie van het neuroblastoom
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The HBP1 tumor suppressor is a druggable ALK downregulated gene controlling MYCN activity
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The HBP1 tumor suppressor is a druggable ALK downregulated gene controlling MYCN activity
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Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastoma
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MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance
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Pharmacologic activation of wild-type p53 by nutlin therapy in childhood cancer
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Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
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Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
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Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
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Identifying and validating DNA methylation biomarkers: the example of neuroblastoma
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Development of an S-G2 micronucleus assay for the detection of in vitro chromosomal radiosensitivity in high-risk women subjected to early mammography screening for breast cancer
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- Journal Article
- A2
- open access
Selective inhibition of the p53–MDM2 interaction by nutlin drugs: a new therapeutic perspective for neuroblastoma
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- Journal Article
- A1
- open access
Effective Alu repeat based RT-qPCR normalization in cancer cell perturbation experiments
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- Journal Article
- A1
- open access
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes
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Promoter methylation analysis identifies prognostic methylation biomarkers in neuroblastoma
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Hepatitis E seroprevalence in Belgium
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Serological assessment of HEV in unexplained acute hepatitis
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- Journal Article
- A1
- open access
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.
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Hepatitis E seroprevalence in East and West Flanders, Belgium
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Hepatitis E seroprevalence in Belgium
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Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
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Kankerceldood en p53
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EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
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Pharmacological activation of p53 and gene therapy as emerging treatment options for neuroblastoma
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Selectieve inhibitie van de p53–MDM2 interactie door nutlin-3 als een nieuwe therapeutische strategie voor neuroblastoom
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Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist Nutlin-3
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New options for molecular therapy of neuroblastoma: from p53 to gene therapy
(2011) -
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
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Evaluation of the analytical performance of nephelometric assays on a Dimension Vista 500 analyzer
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Development of a new method for selective determination of CERA (Continuous Erythropoietin Receptor Activator) in human serum
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Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification
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An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
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- Journal Article
- A1
- open access
A rapid and simple assay to determine pegylated erythropoietin in human serum
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Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2
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- Journal Article
- A2
- open access
Using real-time qPCR to evaluate RNAi-mediated gene silencing
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Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds
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Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53
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Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14(ARF)-MDM2-p53 axis
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Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma
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- Journal Article
- A1
- open access
Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma
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- Journal Article
- A1
- open access
The emerging molecular pathogenesis of neuroblastoma : implications for improved risk assessment and targeted therapy
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- Journal Article
- A2
- open access
Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing
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Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma
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- Journal Article
- A2
- open access
The role of serum erythropoietin levels in diagnosis and classification of erythrocytosis/polycythemia
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Familial and congenital polycythemias: A diagnostic approach
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Granulosa explants in serum-free culture: progesterone as an autocrine survival factor