prof. dr. ir. Matthias D'hooghe
work address
Coupure Links 653, geb. B
9000 Gent
9000 Gent
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- 2018
- Theoretical insight into the regioselective ring-expansions of bicyclic aziridinium ions
- Use of 3-hydroxy-4-(trifluoromethyl)azetidin-2-ones as building blocks for the preparation of trifluoromethyl-containing aminopropanes, 1,3-oxazinan-2-ones, aziridines, and 1,4-dioxan-2-ones
- Synthesis, biology and structure-activity relationships of novel β-enaminone-, aza-aromatic- and thiazepanebased curcuminoids
- Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones
- Formation of fluorinated amido esters through unexpected C3-C4 bond fission in 4-trifluoromethyl-3-oxo-β-lactams
- 2017
- Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of penicillin binding proteins of resistant bacteria
- Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of PBPs of resistant bacteria
- Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of penicillin-binding proteins of resistant bacteria
- Synthesis, biology and structure-activity relationships of novel β-enaminone-, aza-aromatic- and thiazepane-based curcuminoids
- Synthesis of 4-(trifluoromethyl)azetidin-2-one building blocks and transformations into novel CF3-substituted amines and heterocyclic systems