prof. dr. ir. Matthias D'hooghe
work address
Coupure Links 653, geb. B
9000 Gent
9000 Gent
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- 2016
- Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress
- Integrating biocatalytical processes into organic synthesis: nitrilase-mediated conversion of 2-aryl-3-(2-cyanoethyl)aziridines and 4-(cyanomethyl)azetidin-2-ones as a sustainable entry to functionalized γ-lactams and β-lactams
- Diastereoselective synthesis of 3-acetoxy-4-(3-aryloxiran-2-yl)azetidin-2-ones and their transformation into 3,4-fused bicyclic β-lactams
- Synthesis of trifluoromethylated azetidines, aminopropanes, 1,3-oxazinanes, and 1,3-oxazinan-2-ones starting from 4-trifluoromethyl-β-lactam building blocks
- Synthesis and cytotoxic evaluation of novel indenoisoquinolinepropan-2-ol hybrids
- 2015
- Synthesis of novel thymine-β-lactam hybrids and evaluation of their anti-tumor activity
- Synthesis and anticancer properties of new (dihydro)pyranonaphthoquinones and their epoxy analogs
- Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors
- Expedient stereoselective synthesis of new dihydropyrano- and dihydrofuranonaphthoquinones
- Synthesis and antimicrobial/cytotoxic assessment of ferrocenyl oxazinanes, oxazinan-2-ones, and tetrahydropyrimidin-2-ones