prof. dr. ir. Matthias D'hooghe
- Work address
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Coupure Links 653, geb. B
9000 Gent - Matthias.Dhooghe@UGent.be
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Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition
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- journalArticle
- A1
- open access
Synthesis of Novel Aza‐aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines
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Exploring the sequence diversity in glycoside hydrolase family 13_18 reveals a novel glucosylglycerol phosphorylase
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Theoretical insight into the regioselective ring-expansions of bicyclic aziridinium ions
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Use of 3-hydroxy-4-(trifluoromethyl)azetidin-2-ones as building blocks for the preparation of trifluoromethyl-containing aminopropanes, 1,3-oxazinan-2-ones, aziridines, and 1,4-dioxan-2-ones
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Synthesis, biology and structure-activity relationships of novel β-enaminone-, aza-aromatic- and thiazepanebased curcuminoids
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Antibacterial and β-lactamase inhibitory activity of monocyclic β-lactams
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Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones
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Formation of fluorinated amido esters through unexpected C3-C4 bond fission in 4-trifluoromethyl-3-oxo-β-lactams
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Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of penicillin binding proteins of resistant bacteria