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Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis
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- Journal Article
- A1
- open access
Reflective multi-immersion microscope objectives inspired by the Schmidt telescope
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- Journal Article
- A1
- open access
HNF1B alters an evolutionarily conserved nephrogenic program of target genes
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- Journal Article
- A1
- open access
Genetic variants in ARHGEF6 cause congenital anomalies of the kidneys and urinary tract in humans, mice, and frogs
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Identifying and characterizing EZH2 as a druggable dependency factor for desmoid tumors in a genetic Xenopus tropicalis model for Gardner's Syndrome
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- Journal Article
- A1
- open access
Deep learning is widely applicable to phenotyping embryonic development and disease
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CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
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- Journal Article
- A1
- open access
Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos
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RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis
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Homozygous null TBX4 mutations lead to posterior amelia with pelvic and pulmonary hypoplasia
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CRISPR/Cas9-mediated cancer modeling and identification of cancer cell vulnerabilities in Xenopus tropicalis
(2019) -
CRISPR/Cas9 mediated knockout of rcbtb1 in Xenopus tropicalis to model RCBTB1-associated retinal disease
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CRISPR/Cas9 mediated knockout of rcbtb1 in Xenopus tropicalis to model RCBTB1-associated retinal disease
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Methods for CRISPR/Cas9 Xenopus tropicalis tissue-specific multiplex genome engineering
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Cancer models in Xenopus tropicalis by CRISPR/Cas9 mediated knockout of tumor suppressors
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Genotyping of CRISPR/Cas9 genome edited Xenopus tropicalis
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CRISPR/Cas9 disease models in zebrafish and Xenopus : the genetic renaissance of fish and frogs
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RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6
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CRISPR/Cas9-mediated knockout of Rb1 in Xenopus tropicalis
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- Conference Paper
- C3
- open access
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis
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TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models
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- Journal Article
- A1
- open access
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis
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TALEN mediated mutation of apc and β-catenin in Xenopus tropicalis as powerful models for Wnt driven cancer and Familial Adenomatous Polyposis (FAP)
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- Journal Article
- A2
- open access
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis