Daan Van Hauwermeiren
- ORCID iD
- 0000-0002-8362-0664
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Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics
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Validation of model-based design of experiments for continuous wet granulation and drying
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T-shaped partial least squares for high-dosed new active pharmaceutical ingredients in continuous twin-screw wet granulation : granule size prediction with limited material information
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An in silico framework for the robust tuning of an MPC for a continuous blender in a production line for pharmaceutical oral solid dosages.
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Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability
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An extended 3-compartmental model for describing step-change experiments in pharmaceutical twin-screw feeders at different refill regimes
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- Journal Article
- A1
- open access
Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation
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- Journal Article
- A1
- open access
Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation
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- Journal Article
- A2
- open access
Analysis of the influence of process and formulation properties on the drying behavior of pharmaceutical granules in a semi-continuous fluid bed drying system
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- Journal Article
- A1
- open access
Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity
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Towards a generic population balance model for twin-screw wet granulation : from material properties to particle size distribution
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Two-dimensional population balance model for twin-screw wet granulation : model development and calibration based on particle size distribution and porosity
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In-depth analysis of the impacts of material properties on size distributions in continuous twin-screw wet granulation to construct a generic 1D population balance model
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An extended 3-compartment model for describing step change experiments in pharmaceutical twin-screw feeders at different refill regimes
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- Conference Paper
- C3
- open access
An extended 3-D compartment model for describing step-change experiments in pharmaceutical feeders for different refill regimes
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- Conference Paper
- C3
- open access
An extended 3-compartmental model for describing step-change experiments in pharmaceutical twin-screw feeders at different refill regimes
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- Conference Paper
- C3
- open access
Model-based design of experiments in drug product development in continuous manufacturing
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- Journal Article
- A1
- open access
TPLS as predictive platform for twin-screw wet granulation process and formulation development
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- Journal Article
- A1
- open access
Improvement of a 1D population balance model for twin-screw wet granulation by using identifiability analysis
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In-line temperature measurement to improve the understanding of the wetting phase in twin-screw wet granulation and its use in process development
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- PhD Thesis
- open access
On the simulation of particle size distributions in continuous pharmaceutical wet granulation
(2020) -
- Journal Article
- A1
- open access
Predicting pharmaceutical particle size distributions using kernel mean embedding
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Population balance modelling for twin-screw wet granulation : insight in the notion of distance between distributions and the need for identifiable models for good model predictive power
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Kernel mean embedding of distributions : a new data-driven model approach for modelling a continuous pharmaceutical twin-screw granulation process
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Heat transfer evaluation during twin-screw wet granulation in view of detailed process understanding
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Towards a generic model for twin-screw wet granulation
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On the modelling of granule size distributions in twin-screw wet granulation : calibration of a novel compartmental population balance model
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- Conference Paper
- C3
- open access
On the identifiability of kernels for Population Balance Modelling
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Model-based NIR spectroscopy implementation for in-line assay monitoring during a pharmaceutical suspension manufacturing process
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- Conference Paper
- C3
- open access
Towards a general model for twin-screw wet granulation : application of a novel validated PBM model to a hydrophilic compound and linking model parameters to blend properties
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Application of iterative robust model-based optimal experimental design for the calibration of biocatalytic models
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In-depth experimental analysis of pharmaceutical twin-screw wet granulation in view of detailed process understanding
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- Conference Paper
- C3
- open access
Towards a general model for twin-screw wet granulation : validation of a PBM model through linking calibrated model parameters to process conditions
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- Conference Paper
- C3
- open access
Towards a general model for twin-screw wet granulation : development and calibration of a novel three compartmental PBM model
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Methodology and pitfalls when calibrating a PBM : the case of twin-screw wet granulation
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- Conference Paper
- C1
- open access
Methodology and pitfalls when calibrating a PBM : the case of twin-screw wet granulation
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- Conference Paper
- C3
- open access
Model-based process analysis in continuous manufacturing of pharmaceuticals : calibration of a fluid bed dryer model
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- Conference Paper
- C3
- open access
Methodology and pitfalls when calibrating a PBM : the case of twin-screw wet granulation
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The potential of using microreactors for the enzymatic production of unstable intermediates
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Quantifying the importance of flow maldistribution in numbered-up microreactors
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A generic model-based methodology for quantification of mass transfer limitations in microreactors
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- Conference Paper
- C3
- open access
A case study on robust optimal experimental design for model calibration of ω-transaminase
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- Conference Paper
- C1
- open access
Model-based analysis of mass transfer limitations in microreactors