apr. Sophie Steeland

Journal Article
A1
open access

A study of cecal ligation and puncture-induced sepsis in tissue-specific tumor necrosis factor receptor 1-deficient mice

Jolien Vandewalle (UGent) , Sophie Steeland (UGent) , Sara Van Ryckeghem (UGent) , Melanie Eggermont (UGent) , Elien Van Wonterghem (UGent) , Roosmarijn Vandenbroucke (UGent) and Claude Libert (UGent)

(2019) FRONTIERS IN IMMUNOLOGY. 10.

Add to list

Journal Article
A1
open access

Choroid plexus tumor necrosis factor receptor 1 : a new neuroinflammatory piece of the complex Alzheimer's disease puzzle

Sophie Steeland (UGent) and Roosmarijn Vandenbroucke (UGent)

(2019) NEURAL REGENERATION RESEARCH. 14(7). p.1144-1147

Add to list

Journal Article
A1
open access

A new venue of TNF targeting

Sophie Steeland (UGent) , Claude Libert (UGent) and Roosmarijn Vandenbroucke (UGent)

(2018) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 19(5).

Add to list

Journal Article
A1
open access

Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease

Sophie Steeland (UGent) , Nina Gorlé, Charysse Vandendriessche (UGent) , Sriram Balusu (UGent) , Marjana Brkić, Caroline Van Cauwenberghe (UGent) , Griet Van Imschoot (UGent) , Elien Van Wonterghem (UGent) , Riet De Rycke (UGent) , Anna Kremer (UGent) , et al.

(2018) EMBO MOLECULAR MEDICINE. 10(4).

Add to list

Simultaneous inhibition of tumor necrosis factor receptor 1 and matrix metalloproteinase 8 completely protects against acute inflammation and sepsis

Sophie Steeland (UGent) , Sara Van Ryckeghem (UGent) , Jolien Vandewalle (UGent) , Marlies Ballegeer (UGent) , Elien Van Wonterghem (UGent) , Melanie Eggermont (UGent) , Johan Decruyenaere (UGent) , Liesbet De Bus (UGent) , Claude Libert (UGent) and Roosmarijn Vandenbroucke (UGent)

(2018) CRITICAL CARE MEDICINE. 46(1). p.e67-e75

Add to list

PhD Thesis

Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases

Sophie Steeland (UGent)

(2017)

Add to list

Journal Article
A1
open access

TNFR1 inhibition with a nanobody protects against EAE development in mice

Sophie Steeland (UGent) , Sara Van Ryckeghem (UGent) , Griet Van Imschoot (UGent) , Riet De Rycke (UGent) , Wendy Toussaint (UGent) , Leen Vanhoutte (UGent) , Christian Vanhove (UGent) , Filip De Vos (UGent) , Roosmarijn Vandenbroucke (UGent) and Claude Libert (UGent)

(2017) SCIENTIFIC REPORTS. 7.

Add to list

Nanobodies as therapeutics: big opportunities for small antibodies

Sophie Steeland (UGent) , Roosmarijn Vandenbroucke (UGent) and Claude Libert (UGent)

(2016) DRUG DISCOVERY TODAY. 21(7). p.1076-1113

Add to list

Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8

Delphine Demeestere (UGent) , Eline Dejonckheere (UGent) , Sophie Steeland (UGent) , Paco Hulpiau (UGent) , Jurgen Haustraete (UGent) , Nick Devoogdt, Rielana Wichert, Christoph Becker-Pauly, Elien Van Wonterghem (UGent) , Sylviane Dewaele (UGent) , et al.

(2016) MOLECULAR THERAPY. 24(5). p.890-902

Add to list

Efficient analysis of mouse genome sequences reveal many nonsense variants

Sophie Steeland (UGent) , Steven Timmermans (UGent) , Sara Van Ryckeghem (UGent) , Paco Hulpiau (UGent) , Yvan Saeys (UGent) , Marc Van Montagu (UGent) , Roosmarijn Vandenbroucke (UGent) and Claude Libert (UGent)

(2016) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113(20). p.5670-5675

Add to list

Journal Article
A1
open access

Topical imiquimod yields systemic effects due to unintended oral uptake

Lynda Grine (UGent) , Sophie Steeland (UGent) , Sara Van Ryckeghem (UGent) , Marlies Ballegeer (UGent) , Stefan Lienenklaus, Siegfried Weiss, Niek Sanders (UGent) , Roosmarijn Vandenbroucke (UGent) and Claude Libert (UGent)

(2016) SCIENTIFIC REPORTS. 6.

Add to list

Journal Article
A1
open access

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1

Leen Puimège (UGent) , Filip Van Hauwermeiren (UGent) , Sophie Steeland (UGent) , Sara Van Ryckeghem (UGent) , Jolien Vandewalle (UGent) , Sofie Lodens, Lien Dejager (UGent) , Sofie Vandevyver (UGent) , Jan Staelens, Steven Timmermans (UGent) , et al.

(2015) EMBO MOLECULAR MEDICINE. 7(8). p.1004-1017

Add to list

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1

Sophie Steeland (UGent) , Leen Puimège (UGent) , Roosmarijn Vandenbroucke (UGent) , Filip Van Hauwermeiren (UGent) , Jurgen Haustraete (UGent) , Nick Devoogdt, Paco Hulpiau (UGent) , Geert Leroux-Roels (UGent) , Debby Laukens (UGent) , Philip Meuleman (UGent) , et al.

(2015) JOURNAL OF BIOLOGICAL CHEMISTRY. 290(7). p.4022-4037

Academic Bibliography

apr. Sophie Steeland

A study of cecal ligation and puncture-induced sepsis in tissue-specific tumor necrosis factor receptor 1-deficient mice

Choroid plexus tumor necrosis factor receptor 1 : a new neuroinflammatory piece of the complex Alzheimer's disease puzzle

A new venue of TNF targeting

Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease

Simultaneous inhibition of tumor necrosis factor receptor 1 and matrix metalloproteinase 8 completely protects against acute inflammation and sepsis

Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases

TNFR1 inhibition with a nanobody protects against EAE development in mice

Nanobodies as therapeutics: big opportunities for small antibodies

Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8

Efficient analysis of mouse genome sequences reveal many nonsense variants

Topical imiquimod yields systemic effects due to unintended oral uptake

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1

Contents

Support

Contact