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Persistence of piperacillin concentrations after treatment discontinuation : in cauda venenum?
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- Conference Paper
- C3
- open access
Quantitation of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)
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Subtherapeutic antimicrobial plasma concentrations with standard amoxicillin-clavulanate dosing regimens in paediatric cardiac surgery patients
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Proficiency testing for meropenem and piperacillin therapeutic drug monitoring : preliminary results from the Belgian Society on Infectiology and Clinical Microbiology Pharmacokinetic-Pharmacodynamic working group
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Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients
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Development and validation of an LC tandem MS assay for the quantification of β-lactam antibiotics in the sputum of cystic fibrosis patients
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- Conference Paper
- C3
- open access
Dosing of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)
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Population pharmacokinetics of continuous infusion piperacillin in critically ill patients
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Dose optimization of piperacillin/tazobactam in critically ill children
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Stability of amoxicillin and amoxicillin/clavulanic acid reconstituted in isotonic saline
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- Conference Paper
- C3
- open access
Piperacollin-tazobactam pharmacokinetis- pharmacodynamics implies a need for higher dosing in critically ill children
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Augmented renal clearance implies a need for increased amoxicillin-clavulanic acid dosing in critically ill children
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Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review
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Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy
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A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients
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- PhD Thesis
- open access
Patient tailored antibiotic therapy in critically ill patients
(2015) -
Subtleties in practical application of prolonged infusion of β-lactam antibiotics
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Comparison of different equations to assess glomerular filtration in critically ill patients
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Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS
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Exploration of the pre-analytical stability of β-lactam antibiotics in plasma and blood: implications for therapeutic drug monitoring and pharmacokinetic studies
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Stability of generic brands of meropenem reconstituted in isotonic saline
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Measuring unbound versus total vancomycin concentrations in serum and plasma: methodological issues and relevance
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Protein binding of vancomycin: the impact of temperature on free plasma concentrations
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Beta-lactam antibiotic dosing during continuous renal replacement therapy: how can we optimize therapy?
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Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures
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Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis
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An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units
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Does consistent piperacillin dosing result in consistent therapeutic concentrations in critically ill patients?: a longitudinal study over an entire antibiotic course
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Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial
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- Book Chapter
- open access
Optimizing β-lactam antibiotic therapy in the critically ill : moving towards patient-tailored antibiotic therapy
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Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients
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- Miscellaneous
- open access
Identifying patients at risk for augmented renal clearance in the ICU : limitations and challenges
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- Journal Article
- A1
- open access
Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?
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TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial
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Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method
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- Conference Paper
- C3
- open access
A UPLC-MS/MS assay for the quantification of meropenem and piperacillin concentrations in human plasma
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Human salivary cortisol, part II: evaluation of an electrochemiluminescence immunoassay (Roche)
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Human salivary cortisol, part I : development and full validation of an LC-MS/MS based method