Department of Biomedical molecular biology
3778 publications
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Age-dependent signature of serum inflammatory cytokines IL-1Ra, IL-1β, IL-6, IL-18, TNF-α, CXCL9 and CXCL10 in healthy children
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- Journal Article
- open access
The Spreading and Effects of Human Recombinant α-Synuclein Preformed Fibrils in the Cerebrospinal Fluid of Mice
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- Journal Article
- A1
- open access
Automated antibody dispensing to improve high-parameter flow cytometry throughput and analysis
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A20 : a jack of all trades
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- Journal Article
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Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
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- Journal Article
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Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma
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- Journal Article
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- open access
Evaluation of single-sample network inference methods for precision oncology
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- Journal Article
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Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease
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- Journal Article
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- open access
Type 1 immunity enables neonatal thymic ILC1 production
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- Journal Article
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- open access
HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening
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SAMHD1 compound heterozygous rare variants associated with moyamoya and mitral valve disease in the absence of other features of Aicardi-Goutières syndrome
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Visualisation of microalgal lipid bodies through electron microscopy
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- Journal Article
- open access
Targeting Efferocytosis in Inflammaging.
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Regulation of inflammasome signaling by the linear deubiquitinase OTULIN
(2024) -
An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology
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- PhD Thesis
- open access
ADAR1 is a central regulator of the dsRNA response : from A-to-Z RNA
(2024) -
Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics
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- Journal Article
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- open access
Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis
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Chimeric and mutant CARD9 constructs enable analyses of conserved and diverged autoinhibition mechanisms in the CARD-CC protein family
(2024) FEBS JOURNAL. -
Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown
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- Journal Article
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A guide to the expanding field of extracellular vesicles and their release in regulated cell death programs
(2024) FEBS JOURNAL. -
Standardization of fluorescent reporter assays in synthetic biology across the visible light spectrum
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- Journal Article
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- open access
Bacterial extracellular vesicles : an emerging avenue to tackle diseases
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- Journal Article
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Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses
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Modelling of rare diseases and developmental processes in Xenopus tropicalis : from retinal degeneration to epidermal structures
(2023) -
Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma
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Spleen function is reduced in individuals with NR5A1 variants with or without a difference of sex development : a cross-sectional study
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Studying microglia and astrocytes in the liver-brain axis during chronic experimental hepatic encephalopathy
(2023) -
- Journal Article
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- open access
Guidelines for establishing a cytometry laboratory
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Time and place: mapping human prenatal macrophages across tissues
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Exploring Paneth cells : uncovering their homeostatic diversity and role in TNF-induced SIRS
(2023) -
- Journal Article
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The autoinflammation-associated NLRC4<SUP>V341A</SUP> mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice
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- Journal Article
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Limitations of PLX3397 as a microglial investigational tool : peripheral and off-target effects dictate the response to inflammation
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- Journal Article
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Defining solute carrier transporter signatures of murine immune cell subsets
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- Journal Article
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Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia
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Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion
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- Journal Article
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- open access
Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma
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- Journal Article
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NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
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- Journal Article
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Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection
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- Journal Article
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GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate
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- Journal Article
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Beyond ferrostatin-1 : a comprehensive review of ferroptosis inhibitors
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- Journal Article
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Laboratory mice with a wild microbiota generate strong allergic immune responses
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- Journal Article
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- open access
Novel insights into double-stranded RNA-mediated immunopathology
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- Journal Article
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- open access
A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS
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- Journal Article
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Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice
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Studying macrophages in the murine steatotic liver using flow cytometry and confocal microscopy
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- Journal Article
- A1
- open access
The Z-nucleic acid sensor ZBP1 in health and disease
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Photothermal nanofibers enable macromolecule delivery in unstimulated human T cells
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- Journal Article
- A1
- open access
Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology
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- Journal Article
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- open access
Alzheimer's disease and age-related changes in the Cu isotopic composition of blood plasma and brain tissues of the APP^(NL-G-F) murine model revealed by multi-collector ICP-mass spectrometry
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- Journal Article
- A1
- open access
The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function
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Syntaxin 18 defects in human and zebrafish unravel key roles in early cartilage and bone development
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- Journal Article
- A1
- open access
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state
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- Journal Article
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- open access
Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis
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- Miscellaneous
- open access
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function
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- Journal Article
- A2
- open access
A concise guide to choosing suitable gene expression systems for recombinant protein production
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Exploring the gut-brain axis, extracellular vesicles and complement in multiple sclerosis
(2023) -
Choroid plexus base barrier cells : the key to understand compartmentalization and immune surveillance at the blood-CFS barrier
(2023) -
Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis
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- Journal Article
- A1
- open access
Exploring species-specificity in TLR4/MD-2 inhibition with amphiphilic lipid a mimicking glycolipids
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- Journal Article
- A1
- open access
Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation
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- Journal Article
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- open access
Cell death checkpoints in the TNF pathway
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Unravelling the role of OTULIN in liver and intestinal pathology
(2023) -
- Journal Article
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- open access
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
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- Journal Article
- A1
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Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression
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- Journal Article
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Functions of the RIP kinase family members in the skin
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- Journal Article
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Molecular systems biology approaches to investigate mechanisms of gut-brain communication in neurological diseases
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- Miscellaneous
- open access
Mitochondrial dysfunction in inflammation and autoimmunity
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- Journal Article
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- open access
Endosperm cell death promoted by NAC transcription factors facilitates embryo invasion in Arabidopsis
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- Journal Article
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- open access
A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19
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- Journal Article
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Sterile triggers drive joint inflammation in TNF‐ and IL-1β‐dependent mouse arthritis models
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- Journal Article
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Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis
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- Journal Article
- A1
- open access
Ferroptosis and pyroptosis signatures in critical COVID-19 patients
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- Journal Article
- A1
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Mousepost 2.0, a major expansion of the resource
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- Journal Article
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- open access
A role for partial epithelial-to-mesenchymal transition in enabling stemness in homeostasis and cancer
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- Journal Article
- A1
- open access
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes
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- Journal Article
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- open access
Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium
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- Miscellaneous
- open access
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis
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- Journal Article
- A1
- open access
Inhibition of RIPK1 kinase does not affect diabetes development : beta-cells survive RIPK1 activation
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- Journal Article
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Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity
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- Journal Article
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The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation
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- Journal Article
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Proteolytic activity of the paracaspase MALT1 is involved in epithelial restitution and mucosal healing
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- Journal Article
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From PERK to RIPK1 : design, synthesis and evaluation of novel potent and selective necroptosis inhibitors
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- Journal Article
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LC3-independent autophagy is vital to prevent TNF cytotoxicity
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- Journal Article
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HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies
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- Miscellaneous
- open access
Novel role for linear ubiquitination in regulating NFAT1 stability
(2023) FEBS JOURNAL. -
- Journal Article
- A1
- open access
Phagocytosis in the retina promotes local insulin production in the eye
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- Journal Article
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Phase separation-based visualization of protein-protein interactions and kinase activities in plants
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Detoxification mechanisms in the TNF pathway
(2023) -
- Journal Article
- A1
- open access
STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity
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Activation and viral escape of ZBP1-mediated host cell death
(2023) -
- Journal Article
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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF
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- Journal Article
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Death by TNF : a road to inflammation
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Therapeutic exploration of ferroptosis in multiple sclerosis
(2023) -
Chronic pathology of experimental Trypanosoma evansi infection is the combined result of an extra-medullary erythropoiesis abrogation, a failing host B cell response, and the induction of a unique Th1 cell population
(2023) -
- Journal Article
- A1
- open access
Circulating cell-free DNA in health and disease : the relationship to health behaviours, ageing phenotypes and metabolomics
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- Journal Article
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- open access
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection
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Exploring the role of RIPK1 in T cell homeostasis
(2023) -
- Journal Article
- A1
- open access
Trial watch : chemotherapy-induced immunogenic cell death in oncology
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- Journal Article
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Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes
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Innate immune sensors balance infection surveillance and autoinflammation
(2023) -
- Miscellaneous
- open access
Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen induced exhaustion
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- Journal Article
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Paneth cells as the cornerstones of intestinal and organismal health : a primer
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Apoptotic cell death in disease : current understanding of the NCCD 2023
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- Journal Article
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LXR signaling controls homeostatic dendritic cell maturation
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- Journal Article
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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage
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Impact of EMT on regulated cell death and immune activation in colorectal cancer
(2023) -
The role of regulated cell death in chronic obstructive pulmonary disease (COPD)
(2023) -
- Journal Article
- A1
- open access
Free complement and complement containing extracellular vesicles as potential biomarkers for neuroinflammatory and neurodegenerative disorders
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- Journal Article
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Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling
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- Journal Article
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Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
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- Journal Article
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- open access
Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism : possible implication for Alzheimer's disease
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- Journal Article
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Reflective multi-immersion microscope objectives inspired by the Schmidt telescope
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- Journal Article
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HNF1B alters an evolutionarily conserved nephrogenic program of target genes
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- Journal Article
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Molecular mechanisms of nemorosone-induced ferroptosis in cancer cells
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- Journal Article
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Caspase inhibition modulates monocyte-derived macrophage polarization in damaged tissues
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- Miscellaneous
- open access
A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19
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- Journal Article
- A1
- open access
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
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- Journal Article
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A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis
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- Journal Article
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Blocking abundant RNA transcripts by high-affinity oligonucleotides during transcriptome library preparation
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- Journal Article
- A2
- open access
From helping to regulating : a transcriptomic profile of Ifng+ Il10+ Il21+ Cd4+ Th1 cells indicates their role in regulating inflammation during experimental trypanosomosis
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- Journal Article
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- open access
A20 is a master switch of IL-33 signalling in macrophages and determines IL-33-induced lung immunity
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- Journal Article
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Pore-forming proteins as drivers of membrane permeabilization in cell death pathways
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- Journal Article
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Normal lymphocyte homeostasis and function in MALT1 protease-resistant HOIL-1 knock-in mice
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- Journal Article
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Glycyrrhizin-based hydrogels accelerate wound healing of normoglycemic and diabetic mouse skin
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- Journal Article
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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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- Journal Article
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Cell behavior changes and enzymatic biodegradation of hybrid electrospun poly(3-hydroxybutyrate)-based scaffolds with an enhanced piezoresponse after the addition of reduced graphene oxide
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- Book Chapter
- open access
Nanobody technology and new molecular biology methods to advance rapid diagnostic test for neglected tropical diseases
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- Journal Article
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Mosaic RBD nanoparticles induce intergenus cross-reactive antibodies and protect against SARS-CoV-2 challenge
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- Journal Article
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Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space
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Studying the pathogenesis of persistent fatigue in inflammatory bowel diseases
(2023) -
- Journal Article
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- open access
Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis
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- Journal Article
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Hepatic glutamine synthetase controls N-5-methylglutamine in homeostasis and cancer
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- Journal Article
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Spatial and temporal regulation of parent-of-origin allelic expression in the endosperm
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- Journal Article
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- open access
Genetic variants in ARHGEF6 cause congenital anomalies of the kidneys and urinary tract in humans, mice, and frogs
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- Journal Article
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The pathogenesis of African trypanosomiasis
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Detection and quantification of protein aggregates in plants
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- Conference Paper
- C3
- open access
Fibroblast-based radiosensitivity assessment for primary immunodeficiency patients
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- Journal Article
- A2
- open access
Effects of different calorie restriction protocols on oxidative stress parameters in a transgenic mouse model of breast cancer
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- Journal Article
- A1
- open access
Long-term chronic caloric restriction alters miRNA profiles in the brain of ageing mice
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- Journal Article
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- open access
Label-free surface enhanced Raman spectroscopy for cancer detection
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- Journal Article
- A1
- open access
Keeping cell death alive : an introduction into the French Cell Death Research Network
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- Journal Article
- A1
- open access
Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells
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- Journal Article
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- open access
Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer's disease
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Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues
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- Journal Article
- A2
- open access
Characterising extracellular vesicles from individual low volume cerebrospinal fluid samples, isolated by SmartSEC
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GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis
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- Journal Article
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- open access
Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease
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- Journal Article
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- open access
Tyramide signal amplification for the immunofluorescent staining of ZBP1-dependent phosphorylation of RIPK3 and MLKL after HSV-1 infection in human cells
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- Journal Article
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- open access
Multi-omics approach dissects cis-regulatory mechanisms underlying North Carolina macular dystrophy, a retinal enhanceropathy
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- Journal Article
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- open access
Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock
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Microdissection and whole mount scanning electron microscopy visualization of mouse choroid plexus
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Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation
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Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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Whole transcriptome profiling of liquid biopsies from tumor xenografted mouse models enables specific monitoring of tumor-derived RNA
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- Journal Article
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- open access
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis
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- Journal Article
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- open access
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
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- Miscellaneous
- open access
Editorial: Post-translational modifications of extracellular signaling molecules and antigens in immune and inflammatory responses
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Infection and immunity : 'There Are Things Out There You (Don't) Need To Know About'
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- Journal Article
- A2
- open access
Opportunities and challenges in interpretable deep learning for drug sensitivity prediction of cancer cells
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Studying the impact of the gastrointestinal bacteria on the brain, focusing on the blood-cerebrospinal fluid barrier and Alzheimer's disease
(2022) -
Uncovering novel cancer driver genes using CRISPR/Cas9 multiplexing in Xenopus tropicalis
(2022) -
Neurometabolic and gliovascular changes in murine hepatic encephalopathy
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Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors
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Assessing impacts of experimental trypanosome infections on B cell memory
(2022) -
Identifying and characterizing EZH2 as a druggable dependency factor for desmoid tumors in a genetic Xenopus tropicalis model for Gardner's Syndrome
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Bovine embryonic stem cells : a challenging approach for the development of cultured meat
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Bovine pluripotent stem cells : a challenging approach for the development of cultured meat
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- Journal Article
- A1
- open access
ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.
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- Journal Article
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Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells
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- Journal Article
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Modifying PCDH19 levels affects cortical interneuron migration
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- Journal Article
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Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics
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- Journal Article
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- open access
Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27
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African trypanosomiasis
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- Journal Article
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Recent progress in diagnosis and treatment of Human African Trypanosomiasis has made the elimination of this disease a realistic target by 2030
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- Journal Article
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Tipping the balance between erythroid cell differentiation and induction of anemia in response to the inflammatory pathology associated with chronic trypanosome infections
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- Journal Article
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- open access
Retrospective in silico mutation profiling of SARS-CoV-2 structural proteins circulating in Uganda by July 2021 : towards refinement of COVID-19 disease vaccines, diagnostics, and therapeutics
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- Journal Article
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- open access
A20 controls RANK-dependent osteoclast formation and bone physiology
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- Miscellaneous
- open access
Editorial : protein phosphorylation and dephosphorylation in plant-microbe interactions
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Spectrally tunable Förster resonance energy transfer-based biosensors using organic dye grafting
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- Journal Article
- A1
- open access
Liver macrophages in health and disease
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- Journal Article
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Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration
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- Journal Article
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A mouse model of hepatic encephalopathy : bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
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- Journal Article
- A2
- open access
Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA
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- Journal Article
- A1
- open access
Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1
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- Miscellaneous
- open access
Phase separation-based visualization of protein-protein interactions and kinase activities in plants
(2022) -
- Miscellaneous
- open access
Phase separation to visualize protein interaction dynamics and post-translational modifications in planta
(2022) -
- Journal Article
- A1
- open access
Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer
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- Journal Article
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A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
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- Journal Article
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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141
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- Journal Article
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Engraftment of allotransplanted tumor cells in adult rag2 mutant Xenopus tropicalis
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- Journal Article
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Local anesthetics elicit immune-dependent anticancer effects
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Identification and functional characterization of CARD14 protein-protein interactions
(2022) -
- Conference Paper
- C3
- open access
Maximal acyclic subgraph optimization for gene regulatory networks
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- Journal Article
- A1
- open access
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements
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- Journal Article
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RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
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A cellular hierarchy in melanoma uncouples growth and metastasis
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Understanding hepatic macrophage phenotypes and functions in metabolic-associated fatty liver disease
(2022) -
Hijacking receptor-mediated transcytosis at the blood-cerebrospinal fluid barrier as delivery route for drugs to the brain
(2022) -
- Journal Article
- A1
- open access
Acute endotoxemia-induced respiratory and intestinal dysbiosis
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- Journal Article
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Interference between ER stress-related bZIP-type and jasmonate-inducible bHLH-type transcription factors in the regulation of triterpene saponin biosynthesis in Medicago truncatula
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- Journal Article
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- open access
SUBATOMIC : a SUbgraph BAsed mulTi-OMIcs clustering framework to analyze integrated multi-edge networks
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- Journal Article
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The tremendous biomedical potential of bacterial extracellular vesicles
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Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment
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- Journal Article
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Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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- Journal Article
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Recent insights into viral infections as a trigger and accelerator in Alzheimer's disease
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- Journal Article
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CARD14 signalling ensures cell survival and cancer associated gene expression in prostate cancer cells
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- Journal Article
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Exploring the therapeutic potential of ectoine in Duchenne Muscular Dystrophy : comparison with taurine, a supplement with known beneficial effects in the mdx mouse
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- Journal Article
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- open access
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial
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- Journal Article
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- open access
N/C interactions are dispensable for normal in vivo functioning of the androgen receptor in male mice
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Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis
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- Journal Article
- A1
- open access
ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation
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- Miscellaneous
- open access
How tech-savvy employees make the difference in core facilities : recognizing core facility expertise with dedicated career tracks
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Clearing your mind : mechanisms of debris clearance after cell death during neural development
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Editor profile : Rudi Beyaert
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- Journal Article
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- open access
The Charcot-Leyden crystal protein Galectin-10 is not a major determinant of human regulatory T-cell function
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- Journal Article
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Novel iron oxide nanoparticles induce ferroptosis in a panel of cancer cell lines
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- Miscellaneous
- open access
Blocking unwanted sequences by target specific high-affinity binding oligonucleotides during transcriptome library preparation
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- Journal Article
- A1
- open access
Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis
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- Journal Article
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Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity
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- Journal Article
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Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
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Drugging the efferocytosis process : concepts and opportunities
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- Journal Article
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Association of cell death markers with tumor immune cell infiltrates after chemo-radiation in cervical cancer
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Investigating the role of MLKL and EVs in cell-cell communication during necroptosis
(2022) -
Exploration of blood-cerebrospinal fluid barrier targeted extracellular vesicles as brain delivery strategy
(2022) -
Therapeutic targeting of ZEB1-mediated EMT in metastatic colorectal cancer
(2022) -
Targeting and regulation of interleukin-33 signalling in lung inflammation
(2022) -
- Miscellaneous
- open access
HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening
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Bi-allelic loss-of-function variants in LTBP1cause autosomal recessive cutis laxa syndrome
(2022) EUROPEAN JOURNAL OF HUMAN GENETICS. In European Journal of Human Genetics 30(supplement 1). p.40-41 -
- Journal Article
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- open access
The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach
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- Journal Article
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Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets
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- Journal Article
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Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria
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- Journal Article
- A1
- open access
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
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- Miscellaneous
- open access
A breath of fresh macrophages ameliorates inflammation in the hypoxic lung
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- Journal Article
- A1
- open access
Pannexin 1 drives efficient epithelial repair after tissue injury
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- Journal Article
- A1
- open access
High-precision isotopic analysis of Cu and Fe via multi-collector inductively coupled plasma-mass spectrometry reveals lipopolysaccharide-induced inflammatory effects in blood plasma and brain tissues
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Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer
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- Journal Article
- A1
- open access
Engineering a highly sensitive biosensor for abscisic acid in mammalian cells
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Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors
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RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
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- Journal Article
- A1
- open access
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes
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- Journal Article
- A1
- open access
NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes
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- Journal Article
- A1
- open access
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice
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- Journal Article
- A1
- open access
Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis
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- Journal Article
- A1
- open access
Coding variants in mouse and rat model organisms : mousepost and ratpost
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- PhD Thesis
- open access
Unraveling the functional roles of endogenous phytohormones in mammals
(2022) -
Detrimental effect of Trypanosoma brucei brucei infection on memory B cells and host ability to recall protective B-cell responses
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Luminescent human iPSC-derived neurospheroids enable modeling of neurotoxicity after oxygen-glucose deprivation
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- Journal Article
- A1
- open access
Live cell tracking of macrophage efferocytosis during Drosophila embryo development in vivo