- Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries
- CC531S-induced damage of the rat liver sinusoidal endothelial lining is mediated by the Fas/FasL pathway
- Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver disease
A comprehensive analysis of hydrogen peroxide-induced gene expression in tobacco
2003) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 100(26). p.16113-16118 Mark(
- Orientation-dependent gene expression with Epstein-Barr virus-derived vectors
- NF-κB activation by tumor necrosis factor and interleukin-1
The role of E-cadherin in epithelial differentiation and cancer progression
2003) Recent Research Development in Cellular Biochemistry. 1. p.33-77 Mark(
- A paradigm for gene regulation: Inflammation, NF-kappa B and PPAR
- Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1)
- Cutaneous breast cancer deposits show distinct growth patterns with different degrees of angiogenesis, hypoxia and fibrin deposition
- Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death
- Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
- Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling
- Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies
- Cytokines, chemokines and growth factors in the pathogenesis and treatment of inflammatory bowel disease
- Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis
- Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
- Defining desmosomal plakophilin-3 interactions
- Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis
Mitochondrial intermembrane proteins in cell death
2003) BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 304(3). p.487-497 Mark(
- Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases
- Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10
- Role of toll-like receptors in pathogen recognition
- Increased fucosylation and reduced branching of serum glycoprotein N-glycans in all known subtypes of congenital disorder of glycosylation I
- Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
- Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells
- Protein disulphide isomerase of Ostertagia ostertagi: an excretory-secretory product of L4 and adult worms?
- Type II autophagic cell death and death-associated protein kinases
- Inhibition of signal transduction pathways involved in inflammation
- DNA viral vectors in gene therapy
- Crohn's disease patients with CARD15 variants have higher risk of developing axial joint involvement
- Antibodies raised against the flagellar pocket fraction of Trypanosoma brucei preferentially recognize HSP60 in cDNA expression library
- Protein binding and functional characterization of plakophilin 2 - Evidence for its diverse roles in desmosomes and beta-catenin signaling.
- DNA binding-independent induction of I kappa B alpha gene transcription by PPAR alpha
- Regulation of T-cell life and death in the periphery.
- Overexpression of alpha(1)-acid glycoprotein in transgenic mice leads to sensitisation to acute colitis.
- Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.
- TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones.
In situ delivery of cytokines by genetically engineered Lactococcus lactis.
2002) ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY. 82(1-4). p.323-331 Mark(
- The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.
- Induction and repression of NF-kappaB-driven inflammatory genes.
- Regulation of the transcriptional activity of the nuclear factor-kappa B p65 subunit.
- Characterization of the interaction between murine tumour necrosis factor and monoclonal antibodies.
- Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type I patients.
- A role for leptin in the systemic inflammatory response syndrome and immune response
- Novel tools for the study of class I alpha-mannosidases: a chromogenic substrate and a substrate-analog inhibitor.
- Caspases are not localized in mitochondria during life or death
- Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
- Rol van microbiologische criteria binnen HACCP
- A transcript encoding a proteasome beta-subunit and a zinc finger protein in Trypanosoma brucei brucei
- Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methyl glyoxal-derived AGE.
- Non-pathogenic trypanosomatid protozoa as a platform for protein research and production.
- A universal role for MyD88 in TLR/IL-1R-mediated signaling
- Isolation and characterization of XKaiso, a transcriptional repressor that associates with the catenin Xp120(ctn) in Xenopus laevis.
- Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not.
- The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail.
The human alpha E-catenin gene CTNNA1: mutational analysis and rare occurrence of a truncated splice variant.
2002) BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. 1574(3). p.262-268 Mark(
- Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells.
- Spontaneous and oncogene-mediated acquisition of the invasive phenotype by cells in culture.
- Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner
- Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei
- Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: preliminary results of a clinical cohort study and molecular observations.
- Relaxation by vasoactive intestinal polypeptide in the gastric fundus of nitric oxide synthase-deficient mice.
- A novel role for p120 catenin in E-cadherin function.
- Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line.
2002) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 99(21). p.13419-13424 Mark(
Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy
2002) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 99(14). p.9340-9345 Mark(
- Bioavailability of recombinant tumor necrosis factor determines its lethality in mice.
- Correlates of malignancy in cultured cells
- Modulation of invasion in vitro and in vivo
Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas
2002) International Review of Cytology : a Survey of Cell Biology. 214. p.225-272 Mark(
- TNF-Mediated toxicity after massive induction of specific CD8(+) T cells following immunization of mice with a tumor-specific peptide.
- Mice lacking a 2-macroglobulin show an increased host defense against Gram-negative bacterial sepsis, but are more susceptible to endotoxic shock.
- Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-kappa B and signal transducer and activator of transcription (STAT) 1.
- The invasion suppressor function of E-cadherin in mammary epitheloid cells
Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer
2002) Molecular and cellular basis for cell to cell interaction: its significance in cancer, p. 63-80 (S. Hirohashi, H.L. Moses, E. Ruoslahti, T. Sugimura, M. Takeichi and M. Terada, Eds.). Proceedings of the 24th International Symposium of the Princess Takamatsu Cancer Research Fund. The Princeton Scientific Publishing Co. Inc. Princeton, New Jersey, USA, 1994. Mark(
- Investigation of tumour-invasion mechanisms.
- A clinio-pathological and biological approach to the function of the c-erbB-2 protein in breast cancer
- Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes
- A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule
- Use of a meltable polyacrylamide matrix for sodium dodecyl sulfate-polyacrylamide gel electrophoresis in a procedure for N-glycan analysis on picomole amounts of glycoproteins.
- Alice in caspase land. A phylogenetic analysis of caspases from worm to man.
- Differential activation of nuclear factor-kappa B by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly.
- HSP70 protects against TNF-induced lethal inflammatory shock.
- In search of sticky protocols.
- Oncogenes and tumor progression:state of the art.
- Molecular mechanisms of cancer invasion
- Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo.
- Fragmin60 encodes an actin-binding protein with a C2 domain and controls actin Thr-203 phosphorylation in Physarum plasmodia and sclerotia.
- A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid
- The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.
- Ultrasensitive profiling and sequencing of N-linked oligosaccharides using standard DNA-sequencing equipment.
- The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness.
- Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAR pathways.
- Quantitative cell dispersion analysis: New test to measure tumor cell aggressiveness.
- Heterotrimers formed by tumor necrosis factors of different species or muteins.
- Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.
- Activated caspase-1 is not a central mediator of inflammation in the course of ischemia-reperfusion.
- Lactococcus lactis, a tool for the delivery of therapeutic proteins. Treatment of IBD.
- Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.