Department of Radiation oncology and experimental cancer research (ceased 1-10-2018)
2386 publications
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VE/VCO2 slope and oxygen uptake efficiency slope in patients with coronary artery disease and intermediate VO2max
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In regards to Allen et al. (Int J radiat oncol biol phys 2006;65: 640-645)
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Involved-field radiotherapy for patients in partial remission after chemotherapy for advanced Hodgkin's lymphoma
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- Conference Paper
- C3
- open access
QSAR directed design, synthesis and evaluation of anti-invasive chalcones and related heterocyclic compounds
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Positron emission tomography-guided, focal-dose escalation using intensity-modulated radiotherapy for head and neck cancer
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Neoadjuvant chemoradiation versus hyperfractionated accelerated radiotherapy in locally advanced rectal cancer
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Recombinant human erythropoietin α modulates the effects of radiotherapy on colorectal cancer microvessels
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Microbial and dietary factors associated with the equaol and 8-prenylnaringenin poducer phenotypes
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Intraoperative high-dose-rate Brachytherapy (IBT) for locally unresectable intraabdominal malignancy
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A possible mechanism of peritoneal pH changes during carbon dioxide pneumoperitoneum
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(99m)Tc-HYNIC Annexin-V imaging of tumors and its relationship to response to radiotherapy and/or chemotherapy
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Microstructural analysis of foam-like structures by use of R2 dispersion
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- Conference Paper
- C1
- open access
Radiation dosimetry in lung equivalent regions by use of polymer gel foams and quantitative magnetization transfer imaging
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Validation of diffusion imaging with anisotropic fiber phantom
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Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy
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PAQAP: a quality assessment protocol for MRI
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- Conference Paper
- C1
- open access
MR engineering research at the Ghent University
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Evaluation of uncertainty-based stopping criteria for Monte Carlo calculations of intensity-modulated radiotherapy and arc therapy patient dose distributions
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Converging expression profiles from oesophageal and colorectal cancer tissues: a comparative analysis using expression microarray.
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Dose-finding study using oxaliplatin in combination with fixed dose gemcitabin and radiotherapy in patients with locally advanced pancreatic or biliary tract cancer.
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Converging expression profiles from esophageal and colorectal cancer tissues: a comparative analysis using expression microarray.
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Microstructural analysis of foam-like structures by use of R2 dispersion
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Assessment of therapy response by DCE-MRI with a macromolecular gadolinium contrast agent.
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Squamous cell carcinoma of the anus: a possible target for EGFR inhibition?
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- Journal Article
- A1
- open access
Lipoplex-loaded microbubbles for gene delivery: A Trojan horse controlled by ultrasound
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Influence of iohexol on the outcome of I131 treatment in cats
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The effect of pipamperone on the binding index of 123I-5I-R91150, a selective 5-HT2A receptor radioligand,in the canine brain
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The use of ketoconozale to improve the dog's brain uptake of the 5-HT-2A receptor radioligand 123I-R-91150
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Measurement of renal function by calculation of fractional uptake of technetium-99m dimercaptosuccinic acid in cats
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The use of HiSPECT in the investigation of the 5-HT2A receptor and DAT status in the gerbil
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Culture of bovine in vitro embryos in the WOW system seems to prevent apoptosis at the blastocyst stage
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Drug trials in humans: Risks in the light of the London catastrophe
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Der Wissenschaftler Friedrich II. (der Staufer)
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Estrogen receptor signaling is an unstable feature of the gonadotropic LβT2 cell line
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The new EANM paediatric dosage card
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Simulation of the diffusion in the interstitial space of a fiber phantom
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A possible mechanism of peritoneal pH changes during carbon dioxide pneumoperitoneum
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Cell motility and breast cancer metastasis.
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Role of adhesion molecules in locoregional cancer spread.
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The anti-invasive and proapoptotic effect of xanthohumol: potential use in cancer.
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The influence of air cavities within the PTV on Monte Carlo-based IMRT optimization
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Quantitative proton magnetic resonance spectroscopy in presence of sidebands
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Efficiently updating and tracking the dominant kernel principal components
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Radiolabelled chemotherapeutics
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IMRT and focused radiotherapy
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Radiochromic EBT film dosimetry: Effect of film orientation and batch on the lateral correction of the scanner.
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The endoplasmic reticulum: A target for new anticancer drugs
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Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: The need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity
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Dosimetric characterization of GafChromic EBT film and its implication on film dosimetry quality assurance
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Precautions and strategies in using a commercial flatbed scanner for radiochromic film dosimetry
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Monte Carlo treatment planning for photon and electron beams
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The value of EDR2 film dosimetry in compensator-based intensity modulated radiation therapy
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IMAT: Remaining potentials
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The need to develop centers for environmental oncology
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Biomonitoring for genotoxic effects has a low sensitivity in terms of cancer risks associated with lifelong exposures starting in utero
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Invloed van industriële chemicaliën op de neurologische en neuropsychologische ontwikkeling van jonge kinderen.
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Chronische vermoeidheid en het binnenhuismilieu.
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Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac JNK-dependent signaling pathways in colon cancer cells
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Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy
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Checking the consistency of the two blood samples slope-intercept method for estimating GFR using the single blood sample formula in children
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Implementation of biologically conformal radiation therapy in the clinic
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Xanthohumol induces in vitro apoptosis in B-CLL cells mediated by non-classical ER stress
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Three dimensional polymer gel dosimetry: State of the art
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Waiting times in the radiotherapy department in gent
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Intensity-modulated radiation therapy for head and neck carcinoma
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Intensity modulating and other radiation therapy devices for dose painting
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The use of magnetic sensors to monitor moderate deep inspiration breath hold during breast irradiation with dynamic MLC compensators
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Magnetic resonance imaging (MRI) anatomy of the prostate and application of MRI in radiotherapy planning
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Quantitative proton magnetic resonance spectroscopy without water suppression
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Simulation and experimental verification of the diffusion in the interstitial space
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A systematic comparison of absolute quantification schemes for proton magnetic resonance spectroscopy in presence of standing waves
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Quantifying the diffusion in an anisotropic fiber phantom
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Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy
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Mismatch of F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) and Tc-99m pertechnetate single photon emission computed tomography (SPECT) in a euthyroid multinodular goiter
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Differences of cortical 5-HT2A receptor binding index with SPECT in subtypes of anorexia nervosa: Relationship with personality traits?
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Monte Carlo modeling of the ModuLeaf miniature MLC for small field dosimetry and quality assurance of the clinical treatment planning system
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- Journal Article
- A1
- open access
Regional variations in semen quality of community-dwelling young men from Flanders are not paralleled by hormonal indices of testicular function
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Predicting risk of radiation-induced lung injury
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The influence of cooling rate on the accuracy of normoxic polymer gel dosimeters
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Edelfosine protects precultured heart fragments against the invasion of malignant cells through altered sialylation
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Deguelin inhibits expression of I kappa B alpha protein and induces apoptosis of B-CLL cells in vitro
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Intensity-modulated radiation therapy for prostate cancer: Late morbidity and results on biochemical control
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Tc-99m-HYNIC Annexin-V imaging of tumors and its relationship to response to radiotherapy and/or chemotherapy
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- Journal Article
- A1
- open access
Estrogen receptor alpha (ER alpha) and insulin-like growth factor I receptor (IGF-IR) cross-talk in the gonadotropic alpha T3-1 cell line
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Measurement techniques, Modeling strategies and pitfalls to avoid when implementing a mini MLC in a non dedicated planning system
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Radiation of the rat brain suppresses seizure-induced Neurogenesis and transiently enhances excitability during kindling acquisition
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The tandem PDZ domains of syntenin promote cell invasion
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Evaluation of pinpoint properties and central electrode material in clinical beam dosimetry by MC calculations
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PCBs and PCDD/FS in fish and fish products and their impact on the human body burden in belgium
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Association of thyroid hormone concentrations with levels of organochlorine compounds in cord blood of neonates
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Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha 1-integrins during colon cancer cell invasion
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Soluble cadherins as cancer biomarkers
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Intestinal bacteria play a crucial role in the carcinogenic risk from 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
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Akt1 & 2 depletion by RNA interference reduced tumor growth and invasion in human colon cancer cells
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The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro alpha-particle radiation
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Does iohexol one day prior to radioiodine treatment, affect absorbed dose in hyperthyroid cats?
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The effect of pipamperone on the binding index of 123I-5I-R91150, a selective 5-HT2A receptor radioligand, in the canine brain
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Measurement of kidney function by calculation of fractional uptake of technetium-99m-dimercaptosuccinic acid in cats
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The use of ketoconozale to improve the dog's brain uptake of the serotonin 2A-receptor radioligand I-123-R91150
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Does regional brain perfusion correlate with eating disorder symptoms in anorexia and bulimia nervosa patients?
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An overview of 50 patients who underwent epilepsy surgery at Ghent University Hospital
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Reproductive parameters of community-dwelling men from 2 regions in flanders are associated with the consumption of self grown vegetables
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Imaging of the serotonin-2A receptor before and after pipamperone administration in the canine brain
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Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro
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Validation of a resolution-independent method for the quantification of I-123-FP-CIT SPELT scans
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The use of HiSPECT in the investigation of the 5-HT2A receptor and DAT status in the Mongolian gerbil
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Comparison of 6 MV and 18 MV photons for IMRT treatment of lung cancer
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Conversion of CT numbers into tissue parameters for Monte Carlo dose calculations: a multi-centre study
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Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis
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Xanthohumol: a new potential proteasome inhibitor that activates the pro-apoptotic arm of the unfolded protein response in B-CLL cells
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- PhD Thesis
- open access
Biologically conformal radiation therapy and Monte Carlo dose calculations in the clinic
(2007) -
- PhD Thesis
- open access
Radiogenomics in gynecological cancer patients
(2007) -
99m TC-HYNIC Annexin-V for monitoring response to chemotherapy : methodology and feasibility studies
(2007) -
Pre-operative combined modality therapy in the management of locally advanced rectal cancer
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Isolated metastasis in the gallbladder from cutaneous melanoma as shown by F-18 fluorodeoxyglucose (FDG) whole body PET/CT scan
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Colon cancer cells: pro-invasive signalling
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Involved-node radiotherapy (INRT) in patients with early Hodgkin lymphoma: concepts and guidelines
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Cost-utility analysis of chemotherapy in symptomatic advanced nonsmall cell lung cancer
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Re-188-HDD/lipiodol therapy for hepatocellular carcinoma: an activity escalation study
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- Journal Article
- A1
- open access
Noninvasive monitoring of radiotherapy-induced microvascular changes using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in a colorectal tumor model
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Biologische landbouw is belangrijk voor de volksgezondheid
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Imaging probes targeting matrix metalloproteinases
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Assessment of supra-additive effects of cytotoxic drugs and low dose rate irradiation in an in vitro model for hepatocellular carcinoma
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Bioavailability of phytoestrogens from soy and hops
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Exploring the 8-PN producer phenotype: an intervention trial with 50 healthy post-menopausal Caucasian women
(2006) -
Exploring the equol producer phenotype: an intervention trial with 100 healthy post-menoapausal Caucasian women
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ARE PHYTOESTROGENS OF ANY HELP
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Optimized segment-aperture mono-arc therapy (OSAMAT) and its application in conformal radiation of oligometstatic prostate cancer: a phase I study
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Relationship between PCBs, dioxins, chlorinated pesticides and fertility problems in young women.
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E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
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Glomerular filtration rate measurement in cats with a single-injection method using chromium-51 ethylene diaminic tetra-acetic acid.
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Unravelling the biological base of behaviour: the role of spect modalities
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Cat brain perfusion with multi-pinhole SPECT imaging
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Regional cerebral bloodflow and binding index of the 5-HT2A receptor in dogs with anxiety disorder
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Serotonin-2A binding index of the 5-HT2A receptor in dogs with anxiety disorder
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Functional renal imaging in cats using 99mTc-DMSA
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A single sample 51Cr-EDTA clearance for the early detection of renal dysfunction in cats
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On the accuracy and precision of gel dosimetry
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Three dimensional radiation dosimetry in lung-equivalent regions by use of a radiation sensitive gel foam: Principles
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Study of density and stability of a lung-equivalent gel
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Flemish serum values of organochlorinated compounds: where are we now? First results of Flemish environment and health survey (FLEHS) 2002-2006
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The Flemish health and environment biomonitoring prgram: relation between PCB levels in cord blood and dietary habits
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Phantom design for diffusion tensor magnetic resonance imaging
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A single measurement-based method for absolute quantification of metabolites by proton magnetic resonance spectroscopy
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Phantom optimization for diffusion tensor magnetic resonance imaging
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Modelling the diffusion in the interstital space of a fiber phantom
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Removal of sideband modulations in 1H MRS without solvent suppression
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Neoadjuvant chemoradiation versus hyperfractionated accelerated radiotherapy (HART) in resectable distal rectal cancer
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Ki-67 and von Willebrand factor: outcome predictors for oesophageal cancer
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Neoadjuvant chemoradiation versus hyperfractionated accelerated radio-therapy (HART) in respectable dital rectal cancer
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Pro-invasive molecular cross-signaling between cancer cells and myofibroblasts
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Tumour markers in andrology
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Growth factor modulation of fibroblast proliferation, differentiation, and invasion: Implications for tissue valve engineering
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Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents
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Are von Willebrand factor and Ki-67 outcome predictors for esophageal cancer?
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Comparative biodistribution study of the new tumor tracer [I-123]-2-iodo-L-phenylalanine with [I-123]-2-iodo-L-tyrosine
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VE/VCO2 slope and oxygen uptake efficiency Sslope in patients with coronary artery disease and intermediate VO2max
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Low-dose whole brain gamma-irradiation accelerates epileptogenesis during hippocampal kindling
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Systemic NO production during (septic) shock depends on parenchymal and not on hematopoietic cells: in vivo iNOS expression pattern in (septic) shock
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2D-3D methods for clinical dose verification
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What precautions should we use with a flatbed scanner for radiochromic film dosimetry
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Anti-invasive and anti-metastasis strategies: New roads, new tools and new hopes
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Revisiting normal Cr-51-ethylenediaminetetraacetic acid clearance values in children
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Variability of the administered radioiodine doses for the treatment of hyperthyroidism in Belgium
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An expert system for the detection of renal obstruction
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Post-test quality control for the single blood sample technique in glomerular filtration rate measurement in children
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Correction factors after having neglected the first exponential in the estimation of chromium-51 EDTA clearance: a reappraisal
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Pediatric applications of renal nuclear medicine
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Sequential Tc-99m-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy
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Intensity-modulated radiotherapy (IMRT) as primary therapy for prostate cancer: The experience of the Ghent University Hospital (GUH).
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Optimized segment-aperture mono-arctherapy (OSAMAT) and its application in conformal radiation of oligometastatic prostate cancer: A phase I study.
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Synthesis and evaluation of a (99m)Technetium labeled chitin-binding protein as potential specific radioligand for the detection of fungal infections in mice
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Fasting blood glucose levels are related to exercise capacity in patients with coronary artery disease
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- Journal Article
- A1
- open access
Serum dioxin-like activity is associated with reproductive parameters in young men from the general Flemish population
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Brain imaging tools in neurosciences
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Pregabalin in central neuropathic pain associated with spinal cord injury - A placebo-controlled trial
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Practical and clinical benefits of radioimmunotherapy lead to advantages in cost-effectiveness in the treatment of patients with non-Hodgkin's lymphoma
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Y-90-lbritumomab tiuxetan: new drug, interesting concept, and encouraging in practice
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Diabetes and impaired fasting glucose as predictors of morbidity and mortality in male coronary artery disease patients with reduced left ventricular function
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Early prediction of endocrine therapy effect in advanced breast cancer patients using Tc-99m-depreotide scintigraphy
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TGF beta 1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors
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Maximum oxygen uptake at peak exercise in elderly patients with coronary artery disease and preserved left ventricular function: The role of inflammation on top of tissue Doppler-derived systolic and diastolic function
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Comparison among tomographic radionuclide ventriculography algorithms for computing left and right ventricular normal limits
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Relationship between QRS duration, left ventricular volumes and prevalence of nonviability in patients with coronary artery disease and severe left ventricular dysfunction
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Soluble N-cadherin in human biological fluids
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I-123/125-labelled 2-iodo-L-phenylalanine and 2-iodo-D-phenylalanine: comparative uptake in various tumour types and biodistribution in mice
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QSAR modeling of anti-invasive activity of organic compounds using structural descriptors
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Differences in tumor-associated protein levels among middle-age Flemish women in association with area of residence and exposure to pollutants
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A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts
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Helicobacter pylori induces gastric epithelial cell invasion in a c-Met and type IV secretion system-dependent manner
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MLC based stereotactic radiosurgery: The accuracy of the collapse cone algorithm of pinnacle 7.4 modelled and controlled using a consistent data set obtained by several independent detectors.
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Implementation and validation of an add-on MLC for Monte Carlo dose calculations in conformal stereotactic radiosurgery
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Re-188-HDD/Lipiodol for hepatocellular carcinoma: our experience with the first 100 treatments.
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Health significance of human biomonitoring data obtained in areas with different environmental loads: Correlation between biomarkers of exposure and biomarkers of effect
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Accuracy of patient dose calculations for IMRT treatment of lung cancer
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18-F-FDG-PET guided IMRT of head and neck cancer - Focal dose escalation phase I study
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- Journal Article
- A1
- open access
Soluble N-cadherin fragment promotes angiogenesis
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VE/Vco(2) slope and oxygen uptake efficiency slope in patients with coronary artery disease and intermediate peakVo(2)
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Comparison of dose-volume histograms of IMRT treatment plans for ethmoid sinus cancer computed by advanced treatment planning systems including Monte Carlo
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Neurohumoral and inflammatory activation in patients with coronary artery disease treated with statins
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Phase II study of a four-week hypofractionated external beam radiotherapy regimen for prostate cancer: Report on acute toxicity
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Implementation of biologically conformal radiation therapy (BCRT) in an algorithmic segmentation-based inverse planning approach
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[F-18]fluoro-deoxy-glucose positron emission tomography ([F-18]FDG-PET) voxel intensity-based intensity-modulated radiation therapy (IMRT) for head and neck cancer
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Definition and delineation of the clinical target volume for rectal cancer
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Synthesis of Tc-99m-HYNIC-interleukin-12, a new specific radiopharmaceutical for imaging T lymphocytes
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Neoadjuvant chemoradiation versus hyperfractionated accelerated radiotherapy (HART) in resectable distal rectal cancer
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The fundamental radiation properties of normoxic polymer gel dosimeters: a comparison between a methacrylic acid based gel and acrylamide based gels
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Phosphorylation on Ser5 increases the F-actin-binding activity of L-plastin and promotes its targeting to sites of actin assembly in cells
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Three dimensional radiation dosimetry in lung-equivalent regions by use of a radiation sensitive gel foam: Proof of principle
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Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations
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In vitro screening for synergism of high-linear energy transfer Bi-213-radiotherapy with other therapeutic agents for the treatment of B-Cell chronic lymphocytic leukemia
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Functional imaging, serotonin and the suicidal brain
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Induction of the adenoma-carcinoma progression and Cdc25A-B phosphatases by the trefoil factor TFF1 in human colon epithelial cells
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Serotonin transporter and dopamine transporter imaging in the canine brain
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Role of adipocyte-derived resistin in breast cancer
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Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric G alpha/G beta gamma protein complex
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Tibolone and its metabolites inhibit invasion of human mammary carcinoma cells in vitro
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- PhD Thesis
- open access
The N-cadherin ectodomain: fate and finction outside the cancer cell
(2006) -
- PhD Thesis
- open access
Intensity modulated radiation therapy and arc therapy: validation and evolution as applied to tumours of the head and neck, abdominal and pelvic regions
(2006) -
Development of a Monte Carlo dose engine for IMRT treatment planning
(2006) -
Film dosimetry for quality assurance in intensity modulated radiotherapy
(2006) -
Changes in cerebellar blood flow after manipulation of the cervical spine using technetium 99m-ethyl cysteinate dimer
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Automatic generation of a plan optimization volume for tangential field breast cancer radiation therapy
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Synthesis, radiosynthesis and in vivo evaluation in mice of [I-123]-(4-fluorophenyl) {1-[2-(4-iodophenyl)ethyl]piperidin-4-yl}methanone for visualization of the 5-HT2A receptor with SPECT
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Imaging of the seroton transporter before and after citalopram administration in canine brain with 123I-betaCIT SPECT
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Initial results of a hardware diffusion head phantom
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Single Measurement-Based Absolute Quantification of Metabolites by Proton Magnetic Resonance Spectroscopy
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Absolute metabolite quantification by proton magnetic resonance spectroscopy: preliminary results
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Density Regularized Fiber Tractography of the Brain White Matter using Diffusion Tensor MRI
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A flexible hardware phantom for validation of diffusion imaging sequences
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P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanoma
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Economic consequence of local control with radiotherapy: cost analyses of internal mammary and medial supraclavicular lymph node radiotherapy in breast cancer
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Quality control of involved-field radiotherapy in patients with advanced Hodgkin's lymphoma (EORTC 20884)
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Overview of national guidelines for infrastructure and staffing of radiotherapy: ESTRO-QUARTS: work package 1
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Towards evidence-based guidelines for radiotherapy infrastructure and staffing needs in Europe: the ESTRO QUARTS project
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Proton beam therapy: too expensive to become true?
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CHART in lung cancer: economic evaluation and incentives for implementation
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Taxol versus paclitaxel beta-cyclodextrin complexes for hyperthermic peritoneal perfusion: an in vivo study
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In vivo mapping of the effects of radiotherapy on neovascular permeability using dynamic contrast enhanced MRI
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- Journal Article
- A1
- open access
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
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Genotoxic and mutagenic activity of environmental air samples from different rural, urban and industrial sites in Flanders, Belgium
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Detailed spatio-temporal solids concentration profiling during batch settling of activated sludge using a radiotracer
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Conversion of CT numbers into tissue parameters for Monte Carlo dose calculations
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IMRT dose distributions for ethmoid sinus cancer calculated by five different treatment planning systems
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The effect of geometrical and scoring voxel dimensions on accuracy and efficacy of Monte Carlo dose calculations for IMRT
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Radiolabeled lipiodol therapy for hepatocellular carcinoma in patients awaiting liver transplantation: pathology of the explant livers and clinical outcome
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QA-QC of IMRT: European Perspective
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LEAD AND CADMIUM LEVELS OF UMBILICAL BLOOD IN LOW AND HIGH EXPOSURE AREAS OF FLANDERS, BELGIUM, ASSESSED WITH HR-ICP-MS
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"Luchtverfrissers"
(2005) -
OMGEVINGSCONCENTRATIES VAN MUTAGENE AGENTIA ALS OORZAAK VAN KANKER: MECHANISTISCHE INZICHTEN