Faculty of Pharmaceutical Sciences

Journal Article

Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)-Lipids for mRNA Lipid Nanoparticle Formulation

Bianka Golba (UGent) , Matthieu Soete (UGent) , Zifu Zhong (UGent) , Niek Sanders (UGent) , Filip Du Prez (UGent) , Hannes Houck (UGent) and Bruno De Geest (UGent)

(2023) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.

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PhD Thesis

High pressure nebulization of smart hydrogels : driving intraperitoneal drug delivery forward

Helena Braet (UGent)

(2023)

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Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation

Michiel Peeters (UGent) , Ana Alejandra Barrera Jiménez (UGent) , Kensaku Matsunami (UGent) , Fanny Stauffer, Ingmar Nopens (UGent) and Thomas De Beer (UGent)

(2023) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 641.

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Journal Article
A2
open access

Clinical outcomes in patients with atrial fibrillation and a history of falls using non-vitamin K antagonist oral anticoagulants : a nationwide cohort study

Maxim Grymonprez (UGent) , Mirko Petrovic (UGent) , Tine De Backer (UGent) , Stephane Steurbaut and Lies Lahousse (UGent)

(2023) IJC HEART & VASCULATURE. 47.

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Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation

Ana Alejandra Barrera Jiménez (UGent) , Kensaku Matsunami (UGent) , Daan Van Hauwermeiren (UGent) , Michiel Peeters (UGent) , Fanny Stauffer, Eduardo dos Santos Schultz, Ashish Kumar (UGent) , Thomas De Beer (UGent) and Ingmar Nopens (UGent)

(2023) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 640.

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Journal Article
A1
open access

Building a human physiologically based pharmacokinetic model for aflatoxin B1 to simulate interactions with drugs

Orphélie Lootens (UGent) , Marthe De Boevre (UGent) , Jia Ning, Elke Gasthuys (UGent) , Jan Van Bocxlaer (UGent) , Sarah De Saeger (UGent) and An Vermeulen (UGent)

(2023) PHARMACEUTICS. 15(3).

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Journal Article
A1
open access

Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice

Olga Krysko (UGent) , Darya Korsakova, Andrea Renate Teufelberger, Amse De Meyer (UGent) , Jill Steels (UGent) , Natalie De Ruyck (UGent) , Judith van Ovost (UGent) , Sharon Van Nevel (UGent) , Gabriële Holtappels (UGent) , Frauke Coppieters (UGent) , et al.

(2023) FRONTIERS IN IMMUNOLOGY. 14.

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PhD Thesis

Unfolding the versatility of laser-induced vapor nanobubbles : from balancing intracellular delivery with regulated cell death to loading of extracellular vesicles

Jana Ramon (UGent)

(2023)

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Journal Article
A1
open access

New insights into the combined toxicity of aflatoxin B1 and fumonisin B1 in HepG2 cells using Seahorse respirometry analysis and RNA transcriptome sequencing

Xiangrong Chen (UGent) , Mohamed Fathi Abdallah (UGent) , Charlotte Grootaert (UGent) , Filip Van Nieuwerburgh (UGent) and Andreja Rajkovic (UGent)

(2023) ENVIRONMENT INTERNATIONAL. 175.

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Journal Article
A1
open access

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore Billiet (UGent) , Laurenz De Cock (UGent) , Guillem Sanchez Sanchez, Rupert Mayer (UGent) , Glenn Goetgeluk (UGent) , Stijn De Munter (UGent) , Melissa Pille (UGent) , Joline Ingels (UGent) , Hanne Jansen (UGent) , Karin Weening (UGent) , et al.

(2023) JOURNAL OF EXPERIMENTAL MEDICINE. 220(6).

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Journal Article
A1
open access

Cathepsin-L secreted by high-quality bovine embryos exerts an embryotrophic effect in vitro

Annelies Raes (UGent) , Eline Wydooghe (UGent) , Krishna Pavani (UGent) , Osvaldo Américo Bogado Pascottini (UGent) , Katleen Van Steendam (UGent) , Maarten Dhaenens (UGent) , Annekatrien Boel (UGent) , Sonia Heras, Björn Heindryckx (UGent) , Luc Peelman (UGent) , et al.

(2023) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 24(7).

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Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation

Ana Alejandra Barrera Jiménez (UGent) , Kensaku Matsunami (UGent) , Daan Van Hauwermeiren (UGent) , Michiel Peeters (UGent) , Fanny Stauffer, Eduardo dos Santos Schultz, Ashish Kumar (UGent) , Thomas De Beer (UGent) and Ingmar Nopens (UGent)

(2023) CHEMICAL ENGINEERING RESEARCH & DESIGN. 193. p.713-724

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Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

Sofie Meulewaeter (UGent) , Gust Nuytten (UGent) , Miffy H.Y. Cheng, Stefaan De Smedt (UGent) , Pieter R. Cullis, Thomas De Beer (UGent) , Ine Lentacker (UGent) and Rein Verbeke (UGent)

(2023) JOURNAL OF CONTROLLED RELEASE. 357. p.149-160

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PhD Thesis

Making the insoluble soluble : PEtOx based amorphous solid dispersions with high drug loadings using solvent electrospinning as a formulation technique

Jana Becelaere (UGent)

(2023)

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Journal Article
A1
open access

Transcriptomics reveal molecular differences in equine oocytes vitrified before and after in vitro maturation

Daniel Angel Velez (UGent) , Tim Meese (UGent) , Mohamed Hedia (UGent) , Andrea Fernandez Montoro (UGent) , Tine De Coster (UGent) , Osvaldo Américo Bogado Pascottini (UGent) , Filip Van Nieuwerburgh (UGent) , Jan Govaere (UGent) , Ann Van Soom (UGent) , Krishna Pavani (UGent) , et al.

(2023) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 24(8).

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RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

Hannelore Van Eeckhoutte (UGent) , Chantal Donovan, Richard Y. Kim, Thomas M. Conlon, Meshal Ansari, Haroon Khan, Ranjith Jayaraman, Nicole G. Hansbro, Yves Dondelinger (UGent) , Tom Delanghe (UGent) , et al.

(2023) EUROPEAN RESPIRATORY JOURNAL. 61(4).

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Every nano-step counts : a critical reflection on do’s and don’ts in researching nanomedicines for retinal gene therapy

Karen Peynshaert (UGent) , Joke Devoldere (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2023) EXPERT OPINION ON DRUG DELIVERY. 20(2). p.259-271

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Journal Article
A1
open access

Comparing the risk of dementia in subjects with atrial fibrillation using non-vitamin K antagonist oral anticoagulants versus vitamin K antagonists : a Belgian nationwide cohort study

Maxim Grymonprez (UGent) , Mirko Petrovic (UGent) , Tine De Backer (UGent) , M Arfan Ikram, Stephane Steurbaut and Lies Lahousse (UGent)

(2023) AGE AND AGEING. 52(3).

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Journal Article
A1
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Impact of frailty on the effectiveness and safety of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation : a nationwide cohort study

Maxim Grymonprez (UGent) , Mirko Petrovic (UGent) , Tine De Backer (UGent) , Stephane Steurbaut and Lies Lahousse (UGent)

(2023) EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES.

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A1
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Cost-effective sequence analysis of 113 genes in 1,192 probands with retinitis pigmentosa and Leber congenital amaurosis

Daan M. Panneman, Rebekkah J. Hitti-Malin, Lara K. Holtes, Suzanne E. de Bruijn, Janine Reurink, Erica G. M. Boonen, Muhammad Imran Khan, Manir Ali, Sten Andréasson, Elfride De Baere (UGent) , et al.

(2023) FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 11.

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Journal Article
A1
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Novel opto-fluidic drug delivery system for efficient cellular transfection

Majid Layachi, Anthony Treizebré, Laurent Hay, David Gilbert, Jean Pesez, Quentin D’Acremont, Kevin Braeckmans (UGent) , Quentin Thommen and Emmanuel Courtade

(2023) JOURNAL OF NANOBIOTECHNOLOGY. 21(1).

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Effects of biologics treatment in type 2-high chronic rhinosinusitis with nasal polyp patients

Sharon Van Nevel (UGent) , Tim Meese (UGent) , Gabriële Holtappels (UGent) , Natalie De Ruyck (UGent) , Stijn Vanhee (UGent) , Nan Zhang (UGent) , Filip Van Nieuwerburgh (UGent) and Claus Bachert (UGent)

(2023) JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. In Journal of Allergy and Clinical Immunology 151(2, Supplement 1). p.AB187-AB187

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Predictive performance of physiologically based pharmacokinetic modelling of beta-lactam antibiotic concentrations in adipose, bone and muscle tissues

Pieter-Jan De Sutter (UGent) , Pieter De Cock (UGent) , TN Johnson, H Musther, Elke Gasthuys (UGent) and An Vermeulen (UGent)

(2023) DRUG METABOLISM AND DISPOSITION. 51(4). p.499-508

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Delivery of macromolecules in unstimulated T cells by photoporation with polydopamine nanoparticles

Dominika Berdecka (UGent) , Aranit Harizaj, Ilia Goemaere (UGent) , Deep Punj (UGent) , Glenn Goetgeluk (UGent) , Stijn De Munter (UGent) , Herlinde De Keersmaecker (UGent) , Veerle Boterberg (UGent) , Peter Dubruel (UGent) , Bart Vandekerckhove (UGent) , et al.

(2023) JOURNAL OF CONTROLLED RELEASE. 354. p.680-693

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Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes

Kensaku Matsunami (UGent) , Tomohiro Miura, Keita Yaginuma, Shuichi Tanabe, Sara Badr and Hirokazu Sugiyama

(2023) COMPUTERS & CHEMICAL ENGINEERING. 171.

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Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?

Tim Boogaerts, Maarten Quireyns, Hans De Loof, Xander Bertels (UGent) , Natan Van Wichelen, Bram Pussig, Jan Saevels, Lies Lahousse (UGent) , Pauline Bonmariage, Wouter Hamelinck, et al.

(2023) SCIENCE OF THE TOTAL ENVIRONMENT. 876.

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Journal Article
A1
open access

Identification of a novel idiopathic epilepsy risk locus and a variant in the CCDC85A gene in the Dutch partridge dog

Evy Beckers (UGent) , Sofie Bhatti (UGent) , Mario Van Poucke (UGent) , Ingeborgh Polis (UGent) , Frédéric Farnir, Filip Van Nieuwerburgh (UGent) , Paul Mandigers, Luc Van Ham (UGent) , Luc Peelman (UGent) and Bart Broeckx (UGent)

(2023) ANIMALS. 13(5).

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Principles of antibodies with ultralong complementarity-determining regions and picobodies

Marcel Fridolin Passon (UGent) , Stefaan De Smedt (UGent) and Hristo Svilenov (UGent)

(2023) BIOTECHNOLOGY ADVANCES. 64.

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Journal Article
A1
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Bacterial quorum-sensing peptides as immune modulators present in systemic circulation

Anton De Spiegeleer (UGent) , Amélie Descamps (UGent) , Srinath Govindarajan (UGent) , Julie Coudenys (UGent) , Kevin Van der borght (UGent) , Hannah Hirmz (UGent) , Nele Van Den Noortgate (UGent) , Dirk Elewaut (UGent) , Bart De Spiegeleer and Evelien Wynendaele (UGent)

(2023) BIOMOLECULES. 13(2).

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Journal Article
A1
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Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

Mona Bové (UGent) , Mette Kolpen, Mads Lichtenberg, Thomas Bjarnsholt and Tom Coenye (UGent)

(2023) MICROBIOLOGY. 169(1).

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Journal Article
A2
open access

High throughput determination of the biofilm prevention concentration for Pseudomonas aeruginosa biofilms using a synthetic cystic fibrosis sputum medium

Amber De Bleeckere (UGent) , Sara Van den Bossche (UGent) , Pieter-Jan De Sutter (UGent) , Tine Beirens, Aurélie Crabbé (UGent) and Tom Coenye (UGent)

(2023) BIOFILM. 5.

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A tapt1 knock-out zebrafish line with aberrant lens development and impaired vision models human early-onset cataract

Tamara Jarayseh (UGent) , Brecht Guillemyn (UGent) , Hanna De Saffel (UGent) , Jan Willem Bek (UGent) , Delfien Syx (UGent) , Sofie Symoens (UGent) , Yannick Gansemans (UGent) , Filip Van Nieuwerburgh (UGent) , Sujatha Jagadeesh, Jayarekha Raja, et al.

(2023) HUMAN GENETICS. 142(3). p.457-476

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Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity

Ana Alejandra Barrera Jiménez (UGent) , Kensaku Matsunami (UGent) , Michael Ghijs (UGent) , Daan Van Hauwermeiren (UGent) , Michiel Peeters (UGent) , Fanny Stauffer, Thomas De Beer (UGent) and Ingmar Nopens (UGent)

(2023) POWDER TECHNOLOGY. 419.

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Journal Article
A1
open access

Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification

Fien Gysens (UGent) , Lisa Ostyn (UGent) , Ellen Goeteyn (UGent) , Eva Blondeel (UGent) , Justine Nuytens (UGent) , Olivier De Wever (UGent) , Eric de Bony de Lavergne (UGent) , Aurélie Crabbé (UGent) and Pieter Mestdagh (UGent)

(2023) SCIENTIFIC REPORTS. 13(1).

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PhD Thesis

A lipid nanoparticle platform for RNA delivery with cationic amphiphilic drugs : merging the best of both worlds

Bram Bogaert (UGent)

(2023)

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Miscellaneous
open access

Elucidating the combined toxicity of aflatoxin B1 and fumonisin B1 on HepG2 cells based on respirometry and transcriptome analyses

Xiangrong Chen (UGent) , Mohamed Fathi Abdallah (UGent) , Charlotte Grootaert (UGent) , Filip Van Nieuwerburgh (UGent) and Andreja Rajkovic (UGent)

(2023) BIORXIV.

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PhD Thesis
open access

Exploring the potential of [18F]AlF-PSMA-11 for prostate cancer imaging

Sarah Piron (UGent)

(2023)

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Miscellaneous

HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization

Laurens Lambrechts (UGent) , Noah Bonine (UGent) , Rita Verstraeten, Marion Pardons (UGent) , Ytse Noppe (UGent) , Sofie Rutsaert (UGent) , Filip Van Nieuwerburgh (UGent) , Wim Van Criekinge (UGent) , Basiel Cole (UGent) and Linos Vandekerckhove (UGent)

(2023) BioRXiv.

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Journal Article
A1
open access

Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties

Hristo Svilenov (UGent) , Paolo Arosio, Tim Menzen, Peter Tessier and Pietro Sormanni

(2023) MABS. 15(1).

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Miscellaneous

Get what you want : identifying antibodies against pre-defined epitopes on Frizzled receptors

Hristo Svilenov (UGent)

(2023) STRUCTURE. 31(1). p.2-3

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PhD Thesis

Continuous tablet manufacturing : experimental and model-based analysis of the twin-screw wet granulation and compression unit operations

Michiel Peeters (UGent)

(2023)

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PhD Thesis

Deciphering the impact of the cystic fibrosis lung microenvironment on antibiotic activity against Pseudomonas aeruginosa

Sara Van den Bossche (UGent)

(2023)

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Journal Article
A1
open access

Micro‐topographies induce epigenetic reprogramming and quiescence in human mesenchymal stem cells

Steven Vermeulen, Bart Van Puyvelde (UGent) , Laura Bengtsson del Barrio, Ruben Almey (UGent) , Bernard K. van der Veer, Dieter Deforce (UGent) , Maarten Dhaenens (UGent) and Jan de Boer

(2023) ADVANCED SCIENCE. 10(1).

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Targeted AURKA degradation : towards new therapeutic agents for neuroblastoma

Muhammad Rishfi (UGent) , Simon Krols (UGent) , Fien Martens (UGent) , Sarah-Lee Bekaert (UGent) , Ellen Sanders (UGent) , Aline Eggermont (UGent) , Fanny De Vloed (UGent) , Joshua Robert Goulding (UGent) , Martijn Risseeuw (UGent) , Jan Molenaar, et al.

(2023) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 247.

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Journal Article
A1
open access

Therapeutic dilemmas with benzodiazepines and Z‑drugs : insomnia and anxiety disorders versus increased fall risk : a clinical review

Andreas Capiau (UGent) , Liesbeth Huys (UGent) , Eveline van Poelgeest, Nathalie van der Velde, Mirko Petrovic (UGent) and Annemie Somers (UGent)

(2023) EUROPEAN GERIATRIC MEDICINE.

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A1
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Deciphering Alternaria metabolic responses in microbial confrontation via an integrated mass spectrometric targeted and non-targeted strategy

Ye Tian, Mohamed Fathi Abdallah (UGent) , Marthe De Boevre (UGent) , Cheng Wang, Kris Audenaert (UGent) , Sarah De Saeger (UGent) and Aibo Wu

(2023) FOOD CHEMISTRY. 404(part B).

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A1
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Insights into the stabilization of interferon alpha by two surfactants revealed by STD-NMR spectroscopy

Hristo Svilenov (UGent) , Katharina T. Kopp, Alexander P. Golovanov, Gerhard Winter and Matja Zalar

(2023) JOURNAL OF PHARMACEUTICAL SCIENCES. 112(2). p.404-410

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Building an understanding of goal-oriented care through the experiences of people living with chronic conditions

Dagje Boeykens (UGent) , Lara Decoster, Dorine Lenoir (UGent) , An De Sutter (UGent) , Reini Haverals (UGent) , Lies Lahousse (UGent) , Peter Pype (UGent) , Dominique Van de Velde (UGent) , Pauline Boeckxstaens (UGent) and Patricia De Vriendt (UGent)

(2023) PATIENT EDUCATION AND COUNSELING. 107.

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Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma

Alberta L. Wang, Lies Lahousse (UGent) , Amber Dahlin, Ahmed Edris Mohamed (UGent) , Michael McGeachie, Sharon M. Lutz, Joanne E. Sordillo, Guy Brusselle (UGent) , Jessica Lasky-Su, Scott T. Weiss, et al.

(2023) THORAX.

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Miscellaneous

Risk stratifying interstitial lung abnormalities to guide early diagnosis interstitial lung diseases

Marlies S Wijsenbeek and Guy Brusselle (UGent)

(2023) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In 207 1. p.9-11