Faculty of Pharmaceutical Sciences

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Pharmacokinetic evaluation of linezolid administered intravenously in obese patients with pneumonia

Feifan Xie (UGent) , Konstantinos Mantzarlis, Polychronis Malliotakis, Vasileios Koulouras, Sophie Degroote (UGent) , Despoina Koulenti, Stijn Blot (UGent) , Koen Boussery (UGent) , Jan Van Bocxlaer (UGent) and Pieter Colin (UGent)

(2019) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY.

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journalArticle
open access

Two-compartment modeling and dynamics of top-sprayed fluidized bed granulator

Gurmeet Kaur, Mehakpreet Singh (UGent) , Themis Matsoukas, Jitendra Kumar, Thomas De Beer (UGent) and Ingmar Nopens (UGent)

(2019) Applied Mathematical Modelling. 68. p.267-280

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journalArticle

Forensic tri-allelic SNP genotyping using nanopore sequencing

Senne Cornelis (UGent) , Yannick Gansemans (UGent) , Ann-Sophie Vander Plaetsen (UGent) , Jana Weymaere (UGent) , Sander Willems (UGent) , Dieter Deforce (UGent) and Filip Van Nieuwerburgh (UGent)

(2019) Forensic Science International: Genetics. 38. p.204-210

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Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria Milani (UGent) , Filip Matthijssens (UGent) , Wouter Van Loocke (UGent) , Kaat Durinck (UGent) , Juliette Roels (UGent) , Sofie Peirs (UGent) , Morgan Thénoz (UGent) , Tim Pieters (UGent) , Lindy Reunes (UGent) , Béatrice Lintermans (UGent) , et al.

(2019) BRITISH JOURNAL OF HAEMATOLOGY.

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bookChapter
open access

Biological control of mycotoxigenic fungi and their toxins : an update for the pre-harvest approach

Mohamed Fathi Abdallah Abdelmohsen (UGent) , Maarten Ameye (UGent) , Sarah De Saeger (UGent) , Kris Audenaert (UGent) and Geert Haesaert (UGent)

(2019) Fungi and mycotoxins : their occurrence, impact on health and the economy as well as pre- and postharvest management strategies [working title].

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Estimating the reliability of low-abundant signals and limited replicate measurements through MS2 peak area in SWATH

Franck Limonier, Sander Willems (UGent) , Geneviève Waeterloos, Myriam Sneyers, Maarten Dhaenens (UGent) and Dieter Deforce (UGent)

(2019) PROTEOMICS.

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Unravelling the metabolic routes of retapamulin : insights into drug development of pleuromutilins

Feifei Sun, Huiyan Zhang, Gerard Gonzales (UGent) , Jinhui Zhou, Yi Li, Jinzhen Zhang, Yue Jin, Zhanhui Wang, Yanshen Li, Xingyuan Cao, et al.

(2019) ANTIMICROBIAL AGENTS AND CHEMOTHERAPY.

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journalArticle
A1
open access

Brand and generic use of inhalation medication and frequency of switching in children and adults : a population-based cohort study

Marjolein Engelkes, Jan C van Blijderveen, Jetty A Overbeek, Josephine Kuiper, Ron CM Herings, Miriam CJM Sturkenboom, Johan C de Jongste, Katia Verhamme (UGent) and Hettie M Janssens

(2019) JOURNAL OF ASTHMA.

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journalArticle
open access

Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

Jakob Bouton, Kristof Van Hecke, Reuven Rasooly and Serge Van Calenbergh

(2018) Beilstein Journal of Organic Chemistry. 14. p.2822-2828

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Acyloxybenzyl and alkoxyalkyl prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents

Charlotte Courtens (UGent) , Martijn Risseeuw (UGent) , Guy Caljon, Paul Cos and Serge Van Calenbergh (UGent)

(2018) ACS MEDICINAL CHEMISTRY LETTERS. 9(10). p.986-989

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Synthesis toward bivalent ligands for the dopamine D2 and metabotropic glutamate 5 receptors

Mingcheng Qian (UGent) , Elise Wouters (UGent) , James AR Dalton, Martijn Risseeuw (UGent) , René Crans (UGent) , Christophe Stove (UGent) , Jesús Giraldo, Kathleen Van Craenenbroeck (UGent) and Serge Van Calenbergh (UGent)

(2018) JOURNAL OF MEDICINAL CHEMISTRY. 61(18). p.8212-8225

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Antibacterial TiO2 coating on titanium substrates by plasma electrolytic oxidation

Monica Thukkaram (UGent) , Pieter Cools (UGent) , Anton Nikiforov (UGent) , Rino Morent (UGent) , Petra Rigole (UGent) , Tom Coenye (UGent) , Lieven De Wilde (UGent) , Kim Verbeken (UGent) and Nathalie De Geyter (UGent)

(2018) COPSA 2018 : proceedings of the conference on cold plasma sources and applications.

Mark

journalArticle

Nanomaterials and molecular transporters to overcome the bacterial envelope barrier: Towards advanced delivery of antibiotics

Rita S. Santos, Céu Figueiredo, Nuno F. Azevedo, Kevin Braeckmans (UGent) and Stefaan De Smedt (UGent)

(2018) Advanced Drug Delivery Reviews. 136-137. p.28-48

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journalArticle

Water-soluble Withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach

Simon Van Herck (UGent) , Behrouz Hassannia (UGent) , Benoit Louage (UGent) , Raquel Pita Compostizo, Ruben De Coen (UGent) , Wim Vanden Berghe, Tom Vanden Berghe (UGent) and Bruno De Geest (UGent)

(2018) European Polymer Journal.

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journalArticle

pH-Sensitive Hydrazone-Linked Doxorubicin Nanogels via Polymeric-Activated Ester Scaffolds: Synthesis, Assembly, and In Vitro and In Vivo Evaluation in Tumor-Bearing Zebrafish

Alexandra Van Driessche (UGent) , Agnese Kocere, Hannelien Everaert, Lutz Nuhn, Simon Van Herck (UGent) , Gareth Griffiths, Federico Fenaroli and Bruno De Geest (UGent)

(2018) Chemistry of Materials.

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journalArticle

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

Federico Fenaroli, Urska Repnik, Yitian Xu, Kerstin Johann, Simon Van Herck (UGent) , Pradip Dey, Frode Miltzov Skjeldal, Dominik M. Frei, Shahla Bagherifam, Agnese Kocere, et al.

(2018) ACS Nano. 12(8). p.8646-8661

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journalArticle

A versatile method for the selective core-crosslinking of hyaluronic acid nanogels via ketone-hydrazide chemistry: from chemical characterization to in vivo biodistribution

Francielle Pelegrin Garcia, Marlène Rippe, Mychelle V. P. Companhoni, Talitha Fernandes Stefanello, Benoit Louage, Simon Van Herck (UGent) , Lucie Sancey, Jean-Luc Coll, Bruno De Geest (UGent) , Celso Vataru Nakamura, et al.

(2018) Biomaterials Science. 6(7). p.1754-1763

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journalArticle

Stability of fumonisin B-1, deoxynivalenol, zearalenone, and T-2 toxin during processing of traditional Nigerian beer and spices

Cynthia Chilaka (UGent) , Marthe De Boevre (UGent) , Olusegun Oladimeji Atanda and Sarah De Saeger (UGent)

(2018) MYCOTOXIN RESEARCH. 34(4). p.229-239

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journalArticle

Capacitive sensor for detection of benzo(a)pyrene in water

Natalia Beloglazova (UGent) , Pieterjan Lenain (UGent) , Esther De Rycke (UGent) , Irina Yu. Goryacheva, Dietmar Knopp and Sarah De Saeger (UGent)

(2018) TALANTA. 190. p.219-225

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journalArticle

Imprinted proteins as a receptor for detection of zearalenone

Pavel Pidenko, Huiyan Zhang (UGent) , Pieterjan Lenain (UGent) , Irina Goryacheva, Sarah De Saeger (UGent) and Natalia Beloglazova (UGent)

(2018) ANALYTICA CHIMICA ACTA. 1040. p.99-104

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journalArticle

Total aflatoxins in complementary foods produced at community levels using locally available ingredients in Ethiopia

Abebe Ayelign, Ashagrie Zewdu Woldegiorgis, Abdulaziz Adish and Sarah De Saeger (UGent)

(2018) FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE. 11(2). p.111-118

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journalArticle

Mycotoxin contamination of sorghum and its contribution to human dietary exposure in four sub-Saharan countries

Geoffrey Ssepuuya, Christof Van Poucke (UGent) , Emmanuel Njumbe Ediage, Catherine Mulholland, Angelika Tritscher, Philippe Verger, Mary Kenny, Catherine Bessy and Sarah De Saeger

(2018) FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 35(7). p.1384-1393

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journalArticle

Outbreak of an acute aflatoxicosis in Tanzania during 2016

Analice Kamala (UGent) , C. Shirima, B. Jani, M. Bakari, H. Sillo, N. Rusibamayila, Sarah De Saeger (UGent) , M. Kimanya, Y. Y. Gong and A. Simba

(2018) WORLD MYCOTOXIN JOURNAL. 11(3). p.311-320

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journalArticle

Ultra-High-Performance Supercritical Fluid Chromatography as a Separation Tool for Fusarium Mycotoxins and Their Modified Forms

Marthe De Boevre (UGent) , Christof Van Poucke (UGent) , Emmanuel Njumbe Ediage, Dana Vanderputten, Anita Van Landschoot (UGent) and Sarah De Saeger (UGent)

(2018) JOURNAL OF AOAC INTERNATIONAL. 101(3). p.627-632

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journalArticle

Hydrolysers of modified mycotoxins in maize: alpha-Amylase and cellulase induce an underestimation of the total aflatoxin content

Arnau Vidal Corominas (UGent) , Sonia Marin, Vicente Sanchis, Sarah De Saeger (UGent) and Marthe De Boevre (UGent)

(2018) FOOD CHEMISTRY. 248. p.86-92

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journalArticle

Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus

Matthew D. Lebar, Jeffrey W. Cary, Rajtilak Majumdar, Carol H. Carter-Wientjes, Brian M. Mack, Qijian Wei, Valdet Uka (UGent) , Sarah De Saeger (UGent) and José Diana Di Mavungu (UGent)

(2018) FUNGAL GENETICS AND BIOLOGY. 116. p.14-23

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journalArticle
A1
open access

Oxygen consumption rate analysis of mitochondrial dysfunction caused by Bacillus cereus cereulide in Caco-2 and HepG2 cells

Marlies Decleer (UGent) , Jelena Jovanovic (UGent) , Anita Vakula, Bozidar Udovicki, Rock-Seth EK Agoua, Annemieke Madder (UGent) , Sarah De Saeger (UGent) and Andreja Rajkovic (UGent)

(2018) TOXINS. 10(7).

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journalArticle
A1
open access

Fungal endophytes control Fusarium graminearum and reduce trichothecenes and zearalenone in maize

Mohamed Fathi Abdallah Abdelmohsen (UGent) , Marthe De Boevre (UGent) , Sofie Landschoot (UGent) , Sarah De Saeger (UGent) , Geert Haesaert (UGent) and Kris Audenaert (UGent)

(2018) TOXINS. 10(12).

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Fungal and mycotoxin contamination of fermented foods from selected South African markets

Ifeoluwa Adekoya, Adewale Obadina, Judith Phoku, Marthe De Boevre (UGent) , Sarah De Saeger (UGent) and Patrick Njobeh

(2018) FOOD CONTROL. 90. p.295-303

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journalArticle

Toxicokinetics of HT-2 Toxin in Rats and Its Metabolic Profile in Livestock and Human Liver Microsomes

Shupeng Yang (UGent) , Huiyan Zhang (UGent) , Marthe De Boevre (UGent) , Jinzhen Zhang, Yanshen Li, Suxia Zhang, Sarah De Saeger (UGent) , Jinhui Zhou, Yi Li and Feifei Sun

(2018) JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 66(30). p.8160-8168

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journalArticle

In-house validation of a rapid and efficient procedure for simultaneous determination of ergot alkaloids and other mycotoxins in wheat and maize

Natalia Arroyo-Manzanares, Karl De Ruyck (UGent) , Valdet Uka (UGent) , Laura Gamiz-Gracia, Ana M. Garcia-Campana, Sarah De Saeger (UGent) and José Diana Di Mavungu (UGent)

(2018) ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 410(22). p.5567-5581

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journalArticle

Deglucosylation of zearalenone-14-glucoside in animals and human liver leads to underestimation of exposure to zearalenone in humans

Shupeng Yang (UGent) , Huiyan Zhang (UGent) , Jinzhen Zhang, Yanshen Li, Yue Jin, Suxia Zhang, Sarah De Saeger (UGent) , Yi Li, Jinhui Zhou, Feifei Sun, et al.

(2018) ARCHIVES OF TOXICOLOGY. 92(9). p.2779-2791

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journalArticle

Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue

Euna Yoo, Alex C. D. Salyer, Michael J. H. Brush, Yupeng Li, Kathryn L. Trautman, Nikunj M. Shukla, Ans De Beuckelaer (UGent) , Stefan Lienenklaus, Kim Deswarte (UGent) , Bart Lambrecht (UGent) , et al.

(2018) BIOCONJUGATE CHEMISTRY. 29(8). p.2741-2754

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conference
open access

Model calibration and validation of a full-scale reverse osmosis process

Dorien Gaublomme (UGent) , Marjolein Vanoppen (UGent) , Bart De Gusseme (UGent) , Séverine Mortier (UGent) , Arne Verliefde (UGent) and Ingmar Nopens (UGent)

(2018) IWA World Water Congress & Exhibition, Abstracts.

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journalArticle

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

Behrouz Hassannia (UGent) , Bartosz Wiernicki (UGent) , Irina Ingold, Feng Qu, Simon Van Herck (UGent) , Yulia Y. Tyurina, Hulya Bayir, Behnaz A. Abhari, Jose Pedro Friedmann Angeli, Sze Men Choi (UGent) , et al.

(2018) JOURNAL OF CLINICAL INVESTIGATION. 128(8). p.3341-3355

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journalArticle

FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles

Lutz Nuhn (UGent) , Simon Van Herck (UGent) , Andreas Best, Kim Deswarte (UGent) , Maria Kokkinopoulou, Ingo Lieberwirth, Kaloian Koynov, Bart Lambrecht (UGent) and Bruno De Geest (UGent)

(2018) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 57(33). p.10760-10764

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journalArticle

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Bo Lou, Ans De Beuckelaer (UGent) , George Dakwar (UGent) , Katrien Remaut (UGent) , Johan Grooten (UGent) , Kevin Braeckmans (UGent) , Bruno De Geest (UGent) , Enrico Mastrobattista, Stefaan De Koker (UGent) and Wim E. Hennink

(2018) JOURNAL OF CONTROLLED RELEASE. 284. p.73-83

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Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Lutz Nuhn (UGent) , Lien Van Hoecke (UGent) , Kim Deswarte (UGent) , Bert Schepens (UGent) , Yupeng Li, Bart Lambrecht (UGent) , Stefaan De Koker (UGent) , Sunil A David, Xavier Saelens (UGent) and Bruno De Geest (UGent)

(2018) BIOMATERIALS. 178. p.643-651

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The signature of the serotonin system in the chronic corticosterone depression model : a study with [18F]MPPF, [18F]altanserin and [11C]DASB

Glenn Pauwelyn (UGent) , Nick Van Laeken (UGent) , Jeroen Verhoeven (UGent) , Filip De Vos (UGent) , Kathelijne Peremans (UGent) , Robrecht Dockx (UGent) , Chris Baeken (UGent) , Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Ken Kersemans (UGent) , et al.

(2018) NEUROPSYCHIATRY. 8(4). p.1377-1390

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journalArticle
open access

Fluorescence Correlation Spectroscopy to find the critical balance between extracellular association and intracellular dissociation of mRNA complexes

Heyang Zhang (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2018) Acta Biomaterialia. 75. p.358-370

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journalArticle
open access

Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy

Pieterjan Merckx (UGent) , Lynn De Backer, Lien Van Hoecke, Roberta Guagliardo (UGent) , Mercedes Echaide, Pieter Baatsen, Bárbara Olmeda, Xavier Saelens (UGent) , Jésus Pérez-Gil, Stefaan De Smedt (UGent) , et al.

(2018) Acta Biomaterialia. 78. p.236-246

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dissertation

Antibiotic susceptibility and evolutionary adaptation of Pseudomonas aeruginosa in a cystic fibrosis multispecies biofilm

Eva Vandeplassche (UGent)

(2018)

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journalArticle
open access

Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze-drying

Pieter-Jan Van Bockstal (UGent) , Séverine Mortier (UGent) , Jos Corver (UGent) , Ingmar Nopens (UGent) , Krist V. Gernaey and Thomas De Beer (UGent)

(2018) European Journal of Pharmaceutics and Biopharmaceutics. 123. p.108-116

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journalArticle
open access

Solution of bivariate aggregation population balance equation: a comparative study

Mehakpreet Singh (UGent) , Gurmeet Kaur, Thomas De Beer (UGent) and Ingmar Nopens (UGent)

(2018) Reaction Kinetics, Mechanisms and Catalysis. 123(2). p.385-401

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journalArticle
open access

Potential of Near-Infrared Chemical Imaging as Process Analytical Technology Tool for Continuous Freeze-Drying

Davinia Brouckaert (UGent) , Laurens De Meyer (UGent) , Brecht Vanbillemont (UGent) , Pieter-Jan Van Bockstal (UGent) , Joris Lammens (UGent) , Séverine Mortier (UGent) , Jos Corver, Chris Vervaet (UGent) , Ingmar Nopens (UGent) and Thomas De Beer (UGent)

(2018) ANALYTICAL CHEMISTRY. 90(7). p.4354-4362

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journalArticle
open access

Developing a framework to model the primary drying step of a continuous freeze-drying process based on infrared radiation

Pieter-Jan Van Bockstal (UGent) , Jos Corver (UGent) , Séverine Mortier (UGent) , Laurens De Meyer (UGent) , Ingmar Nopens (UGent) , Krist V. Gernaey and Thomas De Beer (UGent)

(2018) European Journal of Pharmaceutics and Biopharmaceutics. 127. p.159-170

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journalArticle
open access

Model development and prediction of particle size distribution, density and friability of a comilling operation in a continuous pharmaceutical manufacturing process

Nirupaplava Metta, Maxim Verstraeten (UGent) , Michael Ghijs (UGent) , Ashish Kumar, Elisabeth Schafer, Ravendra Singh, Thomas De Beer (UGent) , Ingmar Nopens (UGent) , Philippe Cappuyns, Ivo Van Assche, et al.

(2018) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 549(1-2). p.271-282

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journalArticle
open access

Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer

Fien De Leersnyder (UGent) , Valérie Vanhoorne (UGent) , H. Bekaert, Jurgen Vercruysse (UGent) , Michael Ghijs (UGent) , Nils Bostijn (UGent) , Maxim Verstraeten (UGent) , P. Cappuyns, I. Van Assche, Y. Vander Heyden, et al.

(2018) European Journal of Pharmaceutical Sciences. 115. p.223-232

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journalArticle

Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency

Guido van Mierlo, René A.M. Dirks, Laura De Clerck (UGent) , Arie B. Brinkman, Michelle Huth, Susan L. Kloet, Nehmé Saksouk, Leonie I. Kroeze, Sander Willems (UGent) , Matthias Farlik, et al.

(2018) Cell Stem Cell.

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Model-based NIR spectroscopy implementation for in-line assay monitoring during a pharmaceutical suspension manufacturing process

Maxim Verstraeten (UGent) , Daan Van Hauwermeiren (UGent) , Mario Hellings, Eline Hermans, Jeroen Geens, Chris Vervaet (UGent) , Ingmar Nopens (UGent) and Thomas De Beer (UGent)

(2018) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 546(1-2). p.247-254

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journalArticle
open access

Mathematical Modelling and Simulation of a Spray Fluidized Bed Granulator

Gurmeet Kaur, Mehakpreet Singh, Jitendra Kumar, Thomas De Beer (UGent) and Ingmar Nopens (UGent)

(2018) PROCESSES. 6(10).

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journalArticle
open access

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Emmy M Dolman, Wouter Van Loocke (UGent) , Moritz Gartlgruber, Carolina de Carvalho Nunes (UGent) , Fanny De Vloed (UGent) , Pauline Depuydt (UGent) , Karen Verboom (UGent) , et al.

(2018) NATURE COMMUNICATIONS. 9.

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journalArticle
open access

Development and validation of an LC–MS/MS method for the simultaneous determination of citrinin and ochratoxin a in a variety of feed and foodstuffs

Celine Meerpoel, Arnau Vidal, José Diana di Mavungu, Bart Huybrechts, Emmanuel K. Tangni, Mathias Devreese, Siska Croubels and Sarah De Saeger

(2018) Journal of Chromatography A. 1580. p.100-109

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Discovery of novel 7-aryl 7-deazapurine 3'-deoxy-ribofuranosyl nucleosides with potent activity against Trypanosoma cruzi

Fabian Hulpia (UGent) , Kristof Van Hecke (UGent) , Cristiane Franca da Silva, Denise da Gama Jaen Batista, Louis Maes, Guy Caljon, Maria de Nazare C Soeiro and Serge Van Calenbergh (UGent)

(2018) JOURNAL OF MEDICINAL CHEMISTRY. 61(20). p.9287-9300

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Platelet-activating factor acetylhydrolase 1B3 (PAFAH1 B3) is required for the formation of the meiotic spindle during in vitro oocyte maturation

Lynn Vandenberghe (UGent) , Björn Heindryckx (UGent) , Katrien Smits (UGent) , Katarzyna Szymanska-Vandendriessche (UGent) , Nerea Ortiz Escribano (UGent) , Minerva Ferrer Buitrago (UGent) , Krishna Pavani (UGent) , Luc Peelman (UGent) , Dieter Deforce (UGent) , Petra De Sutter (UGent) , et al.

(2018) REPRODUCTION FERTILITY AND DEVELOPMENT. 30(12). p.1739-1750

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journalArticle
A1
open access

Skin mucosome activity as an indicator of Batrachochytrium salamandrivorans susceptibility in salamanders

Hannah Keely Smith (UGent) , Frank Pasmans (UGent) , Maarten Dhaenens (UGent) , Dieter Deforce (UGent) , Dries Bonte (UGent) , Kris Verheyen (UGent) , Luc Lens (UGent) and An Martel (UGent)

(2018) PLOS ONE. 13(7).

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journalArticle
A1
open access

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

Eline Teirlinck (UGent) , Ranhua Xiong (UGent) , Toon Brans (UGent) , Katrien Forier (UGent) , Juan Fraire (UGent) , Heleen Van Acker (UGent) , Nele Matthijs (UGent) , Riet De Rycke (UGent) , Stefaan De Smedt (UGent) , Tom Coenye (UGent) , et al.

(2018) NATURE COMMUNICATIONS. 9.

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Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models

Sofie Dhaese (UGent) , Andras Farkas, Pieter Colin (UGent) , Jeffrey Lipman, Veronique Stove (UGent) , Alain Verstraete (UGent) , Jason A Roberts and Jan De Waele (UGent)

(2018) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY.

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Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates

Simon Van Herck (UGent) , Kim Deswarte (UGent) , Lutz Nuhn (UGent) , Zifu Zhong (UGent) , João Portela Catani (UGent) , Yupeng Li, Niek Sanders (UGent) , Stefan Lienenklaus, Stefaan De Koker (UGent) , Bart Lambrecht (UGent) , et al.

(2018) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 140(43). p.14300-14307

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Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses

Lutz Nuhn (UGent) , Stefaan De Koker (UGent) , Sandra Van Lint (UGent) , Zifu Zhong (UGent) , João Portela Catani (UGent) , Francis Combes (UGent) , Kim Deswarte (UGent) , Yupeng Li, Bart Lambrecht (UGent) , Stefan Lienenklaus, et al.

(2018) ADVANCED MATERIALS. 30(45).

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journalArticle
A1
open access

Short tandem repeat analysis after whole genome amplification of single B-lymphoblastoid cells

Lieselot Deleye (UGent) , Ann-Sophie Vander Plaetsen (UGent) , Jana Weymaere (UGent) , Dieter Deforce (UGent) and Filip Van Nieuwerburgh (UGent)

(2018) SCIENTIFIC REPORTS. 8.

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journalArticle
A1
open access

Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels

Yunhui Zhang (UGent) , Andrea Sass (UGent) , Heleen Van Acker (UGent) , Jasper Wille (UGent) , Bruno Verhasselt (UGent) , Filip Van Nieuwerburgh (UGent) , Volkhard Kaever, Aurélie Crabbé (UGent) and Tom Coenye (UGent)

(2018) FRONTIERS IN MICROBIOLOGY. 9.

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Decreased susceptibility of Streptococcus anginosus to vancomycin in a multispecies biofilm is due to increased thickness of the cell wall

Sarah Tavernier (UGent) , Andrea Sass (UGent) , Michiel De Bruyne (UGent) , Femke Baeke (UGent) , Riet De Rycke (UGent) , Aurélie Crabbé (UGent) , Ilse Vandecandelaere (UGent) , Filip Van Nieuwerburgh (UGent) and Tom Coenye (UGent)

(2018) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 73(9). p.2323-2330

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Pulmonary surfactant and drug delivery : focusing on the role of surfactant proteins

Roberta Guagliardo (UGent) , Jésus Pérez-Gil, Stefaan De Smedt (UGent) and Koen Raemdonck (UGent)

(2018) JOURNAL OF CONTROLLED RELEASE.

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The role of PET- and MRI-derived [18F]FET PET parameters in the discrimination of low- and high-grade gliomas

Sam Donche (UGent) , Michaël Henrotte, Stijn Bonte (UGent) , Jeroen Verhoeven (UGent) , Caroline Van den Broecke (UGent) , Marjan Acou (UGent) and Ingeborg Goethals (UGent)

(2018) NEURO-ONCOLOGY. 20(suppl. 3). p.iii241-iii241

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conference
C3
open access

Cost-effectiveness of [18F]FET for therapy assessment of temozolomide for patients with glioblastoma in a Belgian healthcare setting

Tristan Baguet (UGent) , Jeroen Verhoeven (UGent) , Filip De Vos (UGent) and Ingeborg Goethals (UGent)

(2018) NEURO-ONCOLOGY. 20(suppl. 3).

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dissertation

Model-based process analytical technology in continuous manufacturing

Maxim Verstraeten (UGent)

(2018)

Mark

dissertation

Investigating the intracellular delivery of non-viral gene therapeutics : a focus on the endosomal barrier

Lotte Vermeulen (UGent)

(2018)

Mark

dissertation

Formulation design for continuous twin screw wet granulation

Nina Willecke (UGent)

(2018)

Mark

dissertation

Increasing pharmaceutical process understanding for twin-screw extrusion and tablet manufacturing

Wouter Grymonpré (UGent)

(2018)

Mark

Downscaling of the tableting process : feasibility of miniaturized forced feeders on a high-speed rotary tablet press

Wouter Grymonpré (UGent) , Barbora Blahova Prudilova, Valérie Vanhoorne (UGent) , Bernd Van Snick (UGent) , Frederik Detobel, Jean Paul Remon (UGent) , Thomas De Beer (UGent) and Chris Vervaet (UGent)

(2018) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 550(1-2). p.477-485

Mark

Optimizing feed frame design and tableting process parameters to increase die-filling uniformity on a high-speed rotary tablet press

Wouter Grymonpré (UGent) , Valérie Vanhoorne (UGent) , Bernd Van Snick (UGent) , Barbora Blahova Prudilova, Frederik Detobel, Jean Paul Remon (UGent) , Thomas De Beer (UGent) and Chris Vervaet (UGent)

(2018) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 548(1). p.54-61

Mark

Synthesis of a 3'-C-ethynyl-β-D-ribofuranose purine nucleoside library : discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

Fabian Hulpia (UGent) , Sam Noppen, Dominique Schols, Graciela Andrei, Robert Snoeck, Sandra Liekens, Peter Vervaeke and Serge Van Calenbergh (UGent)

(2018) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 157. p.248-267

Mark

dissertation

Design and synthesis of a purine nucleoside library : phenotypic discovery of antikinetoplastid agents

Fabian Hulpia (UGent)

(2018)

Mark

dissertation

Contribution to the characterization of the Aspergillus flavus secondary metabolome through mass spectrometry-based untargeted metabolic profiling

Valdet Uka (UGent)

(2018)

Mark

PK/PD studies in pigs leading to optimization of treatment dose in MNE?

Elke Gasthuys (UGent) , Lien Dossche (UGent) , Siska Croubels (UGent) , Pauline De Bruyne (UGent) , Mathias Devreese (UGent) , An Vermeulen (UGent) and Johan Vande Walle (UGent)

(2018) International Children’s Continence Society, Annual meeting, Abstracts.

Mark

Biological characterisation of somatropin-derived cryptic peptides

Liesa Tack (UGent) , Nathalie Bracke (UGent) , Frederick Verbeke (UGent) , Evelien Wynendaele (UGent) , Ewald Pauwels (UGent) , Alex Maes, Christophe Van de Wiele, Mike Sathekge and Bart De Spiegeleer (UGent)

(2018) INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS.

Mark

Falsification of biotechnology drugs : current dangers and/or future disasters?

Steven Janvier (UGent) , Bart De Spiegeleer (UGent) , Celine Vanhee and Eric Deconinck

(2018) JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 161. p.175-191

Mark

Impurity profiling of the most frequently encountered falsified polypeptide drugs on the Belgian market

Steven Janvier (UGent) , Karlien Cheyns, Michaël Canfyn, Séverine Goscinny, Bart De Spiegeleer (UGent) , Celine Vanhee and Eric Deconinck

(2018) TALANTA. 188. p.795-807

Mark

Regulatory status of N-alkylamide containing health products

Evelien Wynendaele (UGent) , Bart De Spiegeleer (UGent) , Bert Gevaert (UGent) , Yorick Janssens (UGent) , Sultan Suleman, Steven Cattoor, Jimmy Saunders (UGent) and Lieselotte Veryser (UGent)

(2018) REGULATORY TOXICOLOGY AND PHARMACOLOGY. 98. p.215-223

Mark

conference
C3
open access

Residual API on the packaging : a GMP-marker?

Evelien Wynendaele (UGent) , Miguel Colpaert, Anne Kosgei (UGent) , Nathan Debunne (UGent) and Bart De Spiegeleer (UGent)

(2018) DA-PBA 2018 : 11th international symposium on drug analysis ; 29th international symposium on pharmaceutical and biomedical analysis, Abstracts.

Mark

conference
C3
open access

Do quorum sensing peptides play a role in psychiatric disorders?

Evelien Wynendaele (UGent) , Yorick Janssens (UGent) , Nathan Debunne (UGent) , Kurt Audenaert (UGent) and Bart De Spiegeleer (UGent)

(2018) European Peptide symposium, 35th, Abstracts.

Mark

conference
C3
open access

Is there a role for quorum sensing peptides in cancer?

Evelien Wynendaele (UGent) , Yorick Janssens (UGent) , Nathan Debunne (UGent) , Olivier De Wever (UGent) and Bart De Spiegeleer (UGent)

(2018) Bioactive Peptides, 16th Naples workshop, Abstracts.

Mark

The quality of medicines used in children and supplied by private pharmaceutical wholesalers in Kinshasa, Democratic Republic of Congo : a prospective survey

Benedetta Schiavetti, Evelien Wynendaele (UGent) , Bart De Spiegeleer (UGent) , Geremie J Mbinze, Nicodème Kalenda, Roland Marini, Vera Melotte, Epco Hasker, Bruno Meessen, Raffaella Ravinetto, et al.

(2018) AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 98(3). p.894-903

Mark

journalArticle
A1
open access

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

Behrouz Hassannia (UGent) , Bartosz Wiernicki (UGent) , Irina Ingold, Feng Qu, Simon Van Herck (UGent) , Yulia Y. Tyurina, Hülya Bayır, Behnaz A. Abhari, Jose Pedro Friedmann Angeli, Sze Men Choi (UGent) , et al.

(2018) JOURNAL OF CLINICAL INVESTIGATION. 128(8). p.3341-3355

Mark

conference
C3
open access

4"-O-alkylated α-galactosylceramide analogues as iNKT cell antigens : synthetic, biological and structural studies

Jonas Janssens (UGent) , Jing Wang, Aruna Bitra, Tine Decruy (UGent) , Koen Venken (UGent) , Johan Van der Eycken (UGent) , Dirk Elewaut (UGent) , Dirk Zajonc (UGent) and Serge Van Calenbergh (UGent)

(2018) Book of abstracts : XXV EFMC international symposium on medicinal chemistry. p.231-231

Mark

Biogenic volatile compounds (BVOCs) produced by fungal endophytes reduce zearalenone (ZEN) and trichothecenes produced by Fusarium graminearum

Mohamed Fathi Abdallah Abdelmohsen (UGent) , Sofie Landschoot (UGent) , Marthe De Boevre (UGent) , Sarah De Saeger (UGent) , Geert Haesaert (UGent) and Kris Audenaert (UGent)

(2018) MycoKey, 2nd International conference, Abstracts.

Mark

A shared medication scheme for community dwelling older patients with polypharmacy receiving home health care : role of the community pharmacist

Katrien Foubert (UGent) , Els Mehuys (UGent) , Leen Claes (UGent) , Dirk Van Den Abeele, Marleen Haems, Annemie Somers (UGent) , Mirko Petrovic (UGent) and Koen Boussery (UGent)

(2018) ACTA CLINICA BELGICA.

Mark

Test of neural inertia in humans during general anaesthesia

MH Kuizenga, Pieter Colin (UGent) , KMEM Reyntjens, DJ Touw, H Nalbat, FH Knotnerus, HEM Vereecke and Michel Struys (UGent)

(2018) BRITISH JOURNAL OF ANAESTHESIA. 120(3). p.525-536

Mark

Pharmacokinetic-pharmacodynamic model for propofol for broad application in anaesthesia and sedation

DJ Eleveld, Pieter Colin (UGent) , AR Absalom and Michel Struys (UGent)

(2018) BRITISH JOURNAL OF ANAESTHESIA. 120(5). p.942-959

Mark

Black market designer peptides : poison or prejudice

Steven Janvier (UGent)

(2018) DA-PBA 2018 : 11th international symposium on drug analysis ; 29th international symposium on pharmaceutical and biomedical analysis, Abstracts.

Mark

dissertation

Methods matter : towards the implementation of label-free MS in the context of hESC histone epigenetics

Elisabeth Govaert (UGent)

(2018)

Mark

dissertation

Prediction of pediatric pharmacokinetics to optimize dose regimens using bottom-up, top-down and middle-out approaches

Robin Michelet (UGent)

(2018)

Mark

conference
C3
open access

Radiosynthesis and in vivo evaluation of [18F] FABABA, a new ASCT-2 inhibitor

Tristan Baguet (UGent) , Stef De Lombaerde (UGent) , Jeroen Verhoeven (UGent) , Benedicte Descamps (UGent) , Ingeborg Goethals (UGent) , Christian Vanhove (UGent) and Filip De Vos (UGent)

(2018) European Molecular Imaging meeting, 13th, Abstracts.

Mark

journalArticle
A1
open access

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Annah B Wyss, Tamar Sofer, Mi Kyeong Lee, Natalie Terzikhan (UGent) , Jennifer N Nguyen, Lies Lahousse (UGent) , Jeanne C Latourelle, Albert Vernon Smith, Traci M Bartz, Mary F Feitosa, et al.

(2018) NATURE COMMUNICATIONS. 9.

Mark

journalArticle
A1
open access

Activity-based detection and bioanalytical confirmation of a fatal carfentanil intoxication

Annelies Cannaert (UGent) , Lars Ambach (UGent) , Peter Blanckaert and Christophe Stove (UGent)

(2018) FRONTIERS IN PHARMACOLOGY. 9.

Mark

Control of three different continuous pharmaceutical manufacturing processes : use of soft sensors

Jakob Rehrl, Anssi-Pekka Karttunen, Niels Nicolaï (UGent) , Theresa Hoermann, Martin Horn, Ossi Korhonen, Ingmar Nopens (UGent) , Thomas De Beer (UGent) and Johannes G Khinast

(2018) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 543(1-2). p.60-72

Mark

The impact of the injection mold temperature upon polymer crystallization and resulting drug release from immediate and sustained release tablets

Jeroen Van Renterghem (UGent) , Heleen Dhondt, Glenn Verstraete (UGent) , Michiel De Bruyne (UGent) , Chris Vervaet (UGent) and Thomas De Beer (UGent)

(2018) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 541(1-2). p.108-116

Mark

journalArticle
A1
open access

Selective labeling of individual neurons in dense cultured networks with nanoparticle-enhanced photoporation

Ranhua Xiong (UGent) , Peter Verstraelen, Jo Demeester (UGent) , Andre Skirtach (UGent) , Jean-Pierre Timmermans, Stefaan De Smedt (UGent) , Winnok De Vos (UGent) and Kevin Braeckmans (UGent)

(2018) FRONTIERS IN CELLULAR NEUROSCIENCE. 12.

Mark

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : fact or fiction?

Joske Millecam (UGent) , Laura De Clerck (UGent) , Elisabeth Govaert (UGent) , Mathias Devreese (UGent) , Elke Gasthuys (UGent) , Wim Schelstraete (UGent) , Dieter Deforce (UGent) , Lies De Bock, Jan Van Bocxlaer (UGent) , Stanislas Sys (UGent) , et al.

(2018) JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. 41(suppl. 1). p.55-56