Department of Pharmaceutical analysis
2180 publications
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Streptococcal quorum sensing peptide CSP-7 contributes to muscle inflammation and wasting
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- Journal Article
- A1
- open access
Preclinical activity of two paclitaxel nanoparticle formulations after intraperitoneal administration in ovarian cancer murine xenografts
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- Journal Article
- A1
- open access
Impact of model-informed precision dosing in adults receiving vancomycin via continuous infusion : a randomized, controlled clinical trial
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- Journal Article
- A1
- open access
Scenario analysis of vaccine supply for COVID-19 in Japan using mathematical models of infectious diseases
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Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation
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BrainPepPass : a framework based on supervised dimensionality reduction for predicting blood-brain barrier-penetrating peptides
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- Journal Article
- A1
- open access
The development and characterization of in vivo-like three-dimensional models of bronchial epithelial cell lines.
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A colourful way to unravel the important fluidization-related granule size effect on semi-continuous drying
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- Journal Article
- A1
- open access
Characterizing non-covalent protein complexes using asymmetrical flow field-flow fractionation on-line coupled to native mass spectrometry
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- Journal Article
- A1
- open access
Emerging pharmaceutical therapies of Ascidian-derived natural products and derivatives
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- Journal Article
- A1
- open access
Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
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- Journal Article
- A1
- open access
Evaluation of greenness and analytical performances of separative methods for chiral separation of novel lactam-based P2RX7-antagonists
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- Journal Article
- A1
- open access
Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids
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- Journal Article
- A1
- open access
Biofilm antimicrobial susceptibility testing : where are we and where could we be going?
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Effect of poly(vinyl pyrrolidone) on iodine release from acrylate-endcapped urethane-based poly(ethylene glycol) hydrogels as antibacterial wound dressing.
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- Journal Article
- A1
- open access
Pooling isolates to address the diversity in antimicrobial susceptibility of Pseudomonas aeruginosa in cystic fibrosis
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- Journal Article
- A1
- open access
Effect of malate on the activity of ciprofloxacin against Pseudomonas aeruginosa in different in vivo and in vivo-like infection models
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- Journal Article
- A1
- open access
What's in a name? Characteristics of clinical biofilms
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- Journal Article
- A1
- open access
3D-printed wound dressings containing a fosmidomycin-derivative prevent Acinetobacter baumannii biofilm formation
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- Journal Article
- A1
- open access
Environment-functionality-cost balance of an analytical reagent
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Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics
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- Journal Article
- A1
- open access
Development of concentration prediction models for personalized tablet manufacturing using near-infrared spectroscopy
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- Journal Article
- A1
- open access
Validation of model-based design of experiments for continuous wet granulation and drying
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- Journal Article
- A1
- open access
T-shaped partial least squares for high-dosed new active pharmaceutical ingredients in continuous twin-screw wet granulation : granule size prediction with limited material information
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An in silico framework for the robust tuning of an MPC for a continuous blender in a production line for pharmaceutical oral solid dosages.
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A formulation-generic pharmaceutical fluidized bed drying model including granule segregation as a vital component
(2023) -
- Journal Article
- A1
- open access
Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability
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Modulation of bacterial metabolism to potentiate antibiotic efficacy against Pseudomonas aeruginosa biofilm infections
(2023) -
- Journal Article
- A2
- open access
Combining phages and antibiotic to enhance antibiofilm efficacy against an in vitro dual species wound biofilm
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- Journal Article
- A1
- open access
The small RNA NcS25 regulates biological amine-transporting outer membrane porin BCAL3473 in Burkholderia cenocepacia
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- Journal Article
- A2
- open access
In vitro and in vivo evaluation of diethyldithiocarbamate with copper ions and its liposomal formulation for the treatment of Staphylococcus aureus and Staphylococcus epidermidis biofilms
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A systematic review of the use of bacteriophages for in vitro biofilm control
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- Journal Article
- A2
- open access
Toegevoegde waarde van de apotheker bij de aanpak van polymedicatie in de eerstelijnszorg
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Potential role of statins in treatment of acute sarcopenia
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- Journal Article
- A1
- open access
Development of diclofenac sodium 3D printed cylindrical and tubular-shaped tablets through hot melt extrusion and fused deposition modelling techniques
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An extended 3-compartmental model for describing step-change experiments in pharmaceutical twin-screw feeders at different refill regimes
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- Journal Article
- A1
- open access
Commensal bacteria of the lung microbiota synergistically inhibit inflammation in a three-dimensional epithelial cell model
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- Journal Article
- A1
- open access
Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation
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- Journal Article
- A1
- open access
Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation
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Identification of continuous twin-screw melt granulation mechanisms for different screw configurations, process settings and formulation
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- Journal Article
- A1
- open access
Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation
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Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures
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- Journal Article
- A1
- open access
Peptidomics : LC-MS operational parameters do matter
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Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes
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- Journal Article
- A1
- open access
Bacterial quorum-sensing peptides as immune modulators present in systemic circulation
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- Journal Article
- A1
- open access
Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes
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- Journal Article
- A2
- open access
High throughput determination of the biofilm prevention concentration for Pseudomonas aeruginosa biofilms using a synthetic cystic fibrosis sputum medium
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- Journal Article
- A1
- open access
Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity
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- Journal Article
- A1
- open access
Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification
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- PhD Thesis
- open access
Exploring the potential of [18F]AlF-PSMA-11 for prostate cancer imaging
(2023) -
Continuous tablet manufacturing : experimental and model-based analysis of the twin-screw wet granulation and compression unit operations
(2023) -
Deciphering the impact of the cystic fibrosis lung microenvironment on antibiotic activity against Pseudomonas aeruginosa
(2023) -
- Journal Article
- A1
- open access
Quality-by-design principles applied to the establishment of a pharmaceutical quality control laboratory in a resource-limited setting : the lab water
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Sarcopenia : a gut-feeling for quorum sensing peptides and natural killer T cells
(2022) -
Finite element modeling of powder compaction : mini-tablets in comparison with conventionally sized tablets
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Towards a generic population balance model for twin-screw wet granulation : from material properties to particle size distribution
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- Journal Article
- A1
- open access
New concepts in antimicrobial resistance in cystic fibrosis respiratory infections
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18F-PSMA-11 Versus 68Ga-PSMA-11 positron emission tomography/computed tomography for staging and biochemical recurrence of prostate cancer : a prospective double-blind randomised cross-over trial
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- Journal Article
- A1
- open access
Pellicle biofilm formation in Burkholderia cenocepacia J2315 is epigenetically regulated through WspH, a hybrid two-component system kinase-response regulator
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The anti-virulence activity of the non- mevalonate pathway inhibitor FR900098 towards Burkholderia cenocepacia is maintained during experimental evolution
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- Journal Article
- A1
- open access
Phenotypic characterization and heterogeneity among modern clinical isolates of Acinetobacter baumannii
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- Journal Article
- A1
- open access
Antibiofilm activities of borneol-citral-loaded pickering emulsions against Pseudomonas aeruginosa and Staphylococcus aureus in physiologically relevant chronic infection models
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- Journal Article
- A1
- open access
The combination of diethyldithiocarbamate and copper ions is active against Staphylococcus aureus and Staphylococcus epidermidis biofilms in vitro and in vivo
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- Journal Article
- A1
- open access
Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
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- Journal Article
- A1
- open access
Biofilm antimicrobial susceptibility through an experimental evolutionary lens
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Novel insights into the antibiofilm activity of borneol, citral and their combination
(2022) -
Two-dimensional population balance model for twin-screw wet granulation : model development and calibration based on particle size distribution and porosity
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In-depth analysis of the impacts of material properties on size distributions in continuous twin-screw wet granulation to construct a generic 1D population balance model
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- Journal Article
- A2
- open access
Kan een CRP-sneltest in woonzorgcentra het voorschrijven van antibiotica bij lage luchtweginfecties gunstig beïnvloeden?
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- Journal Article
- A1
- open access
Explaining the working mechanism of laser‐activated irrigation and its action on microbial biofilms : a high‐speed imaging study
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- Journal Article
- A1
- open access
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia
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Increasing the applicability of population balance models in continuous pharmaceutical twin-screw wet granulation
(2022) -
An extended 3-compartment model for describing step change experiments in pharmaceutical twin-screw feeders at different refill regimes
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- Conference Paper
- C3
- open access
An extended 3-D compartment model for describing step-change experiments in pharmaceutical feeders for different refill regimes
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- Conference Paper
- C3
- open access
An extended 3-compartmental model for describing step-change experiments in pharmaceutical twin-screw feeders at different refill regimes
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Assessing the evolutionary robustness of anti-biofilm combination therapy
(2022) -
- Journal Article
- A1
- open access
Degradation kinetics of artesunate for the development of an ex-tempore intravenous injection
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- Journal Article
- A1
- open access
Preclinical comparative study of [18F]AlF-PSMA-11 and [18F]PSMA-1007 in varying PSMA expressing tumors
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- Conference Paper
- C3
- open access
Model-based design of experiments in drug product development in continuous manufacturing
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Impact of alternative lubricants on process and tablet quality for direct compression
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- Journal Article
- A1
- open access
The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice : a new factor in the host-microbiome interaction
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- Journal Article
- A2
- open access
Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients
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- Journal Article
- A1
- open access
Continuous direct compression: development of an empirical predictive model and challenges regarding PAT implementation
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- Journal Article
- A1
- open access
In-depth analysis of the long-term processability of materials during continuous feeding
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- Journal Article
- A1
- open access
The effect of binder types on the breakage and drying behavior of granules in a semi-continuous fluid bed dryer after twin screw wet granulation
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- Journal Article
- A1
- open access
Effect of feed frame on lubricant sensitivity during upscaling from a compaction simulator to a rotary tablet press
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- Conference Paper
- C3
- open access
Two-dimensional granule property measurement using hyperspectral imaging in continuous pharmaceutical wet granulation
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- Conference Paper
- C3
- open access
Model-based determination of spatial heterogeneities in a pharmaceutical fluidization process and integration into a mechanistic multi-level drying model
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- Journal Article
- A1
- open access
The role of abdominal drain cultures in managing abdominal infections
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- Journal Article
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- open access
Organic acids and their salts potentiate the activity of selected antibiotics against Pseudomonas aeruginosa biofilms grown in a synthetic cystic fibrosis sputum medium
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- Journal Article
- A1
- open access
The CovRS environmental sensor directly controls the ComRS signaling system to orchestrate competence bimodality in salivarius streptococci
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Development and characterisation of a continuous freeze-drying technology for unit doses
(2022) -
The fitness–fatigue model : what’s in the numbers?
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- Journal Article
- A1
- open access
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
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- Journal Article
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- open access
Accelerated HF‐rTMS modifies SERT availability in the subgenual anterior cingulate cortex : a canine [11C]DASB study on the serotonergic system
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The use of national reimbursement reports to support formulary decisions of the hospital's Drug and Therapeutics Committee : a comparative analysis
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Exploring the in-vivo role of quorum sensing peptides : preclinical and bioanalytical contributions
(2022) -
A fit-for-purpose LC-MS/MS method for the analysis of selected Streptococcal quorum sensing peptides in human saliva
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- Miscellaneous
- open access
Advances in twin-screw granulation
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Analysis and prevention of microbial biofilms on medical devices and in chronic wounds
(2022) -
- Journal Article
- A2
- open access
The role of biofilm formation in the pathogenesis and antimicrobial susceptibility of Cutibacterium acnes
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- Book Chapter
- open access
Liquid chromatography-mass spectrometry (LC-MS) analysis of bioactive peptides
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A bioanalytical screening method for Enterococcus faecalis RNPP-type quorum sensing peptides in murine feces
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- Journal Article
- A1
- open access
Recent advancements in 18F-labeled PSMA targeting PET radiopharmaceuticals
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- Journal Article
- A1
- open access
Statin intake and all-cause mortality among older nursing home residents
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- Journal Article
- A1
- open access
Model systems to study the chronic, polymicrobial infections in cystic fibrosis : current approaches and exploring future directions
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Is monitoring of antiplatelet therapy by light transmission aggregometry dependent on instrument and reagent used?
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Continuous granulation
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- Conference Paper
- C3
- open access
Model-based analysis of breakage in fluid bed drying of continuously produced pharmaceutical wet granules
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- Conference Paper
- C3
- open access
Analysis of fluidization and particle temperature in semicontinuous fluid bed drying of pharmaceutical granules
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- Conference Paper
- C3
- open access
Clarifying the formulation effect on the drying behavior of pharmaceutical granules after wet granulation
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- Journal Article
- A1
- open access
Increasing angiogenesis factors in hypoxic diabetic wound conditions by siRNA delivery : additive effect of LbL-gold nanocarriers and desloratadine-induced lysosomal escape
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- Journal Article
- A1
- open access
Effect of binder type and lubrication method on the binder efficacy for direct compression
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- Journal Article
- A1
- open access
Influence of print settings on the critical quality attributes of extrusion-based 3D-printed caplets : a quality-by-design approach
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- Journal Article
- A1
- open access
Determination of a quantitative relationship between material properties, process settings and screw feeding behavior via multivariate data-analysis
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- Journal Article
- A1
- open access
A NIR-based study of desorption kinetics during continuous spin freeze-drying
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Melt granulation
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- Journal Article
- A1
- open access
Development and application of a mechanistic cooling and freezing model of the spin freezing step within the framework of continuous freeze-drying
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- Journal Article
- A1
- open access
Spin freezing and its impact on pore size, tortuosity and solid state
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Evaluation of torque as an in-process control for granule size during twin-screw wet granulation
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- Journal Article
- A1
- open access
Macrophage reprogramming into a pro-healing phenotype by siRNA delivered with LBL assembled nanocomplexes for wound healing applications
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Dynamic constitutional frameworks as antibacterial and antibiofilm agents
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Pillar[5]arene-based polycationic glyco[2]rotaxanes designed as Pseudomonas aeruginosa antibiofilm agents
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- Journal Article
- A1
- open access
TPLS as predictive platform for twin-screw wet granulation process and formulation development
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- Journal Article
- A1
- open access
Improvement of a 1D population balance model for twin-screw wet granulation by using identifiability analysis
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- Journal Article
- A1
- open access
Biosynthesis of ditropolonyl sulfide, an antibacterial compound produced by Burkholderia cepacia complex strain R-12632
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The influence of different training load quantification methods on the fitness-fatigue model
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- Journal Article
- A2
- open access
Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1
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A predictive tableting platform for direct compression processes
(2021) -
- Journal Article
- A1
- open access
Impact of the molar activity and PSMA expression level on [18F]AlF-PSMA-11 uptake in prostate cancer
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- Journal Article
- A1
- open access
Analysis of the effects of process parameters on start-up operation in continuous wet granulation
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- Journal Article
- A1
- open access
Off-patent biologicals and biosimilars tendering in Europe : a proposal towards more sustainable practices
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BBPpred : sequence-based prediction of blood-brain barrier peptides with feature representation learning and logistic regression
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- Journal Article
- A1
- open access
Conformational stability as a quality attribute for the cell therapy raw material human serum albumin
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- Journal Article
- A1
- open access
Apoptosis imaging in oncology by means of positron emission tomography : a review
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- Miscellaneous
- open access
Adjunctive use of statins for COVID-19
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Faecal microbiota transplants : why do we not consider them as Advanced Therapy Medicinal Products?
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Acute sarcopenia changes following hospitalization : influence of pre-admission care dependency level
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- Journal Article
- A2
- open access
Sustainability in drug discovery
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- Journal Article
- A1
- open access
Particle-scale modeling to understand liquid distribution in twin-screw wet granulation
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- Miscellaneous
- open access
Do results obtained with RNA-sequencing require independent verification?
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The quorum-sensing inhibitor furanone C-30 rapidly loses its tobramycin-potentiating activity against Pseudomonas aeruginosa biofilms during experimental evolution
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Colloidal silver combating pathogenic Pseudomonas aeruginosa and MRSA in chronic rhinosinusitis
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- Journal Article
- A1
- open access
Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K+ leakage
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- Journal Article
- A1
- open access
Antistaphylococcal activity of the FtsZ inhibitor C109
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- Journal Article
- A1
- open access
Interlaboratory study for the evaluation of three microtiter plate-based biofilm quantification methods
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Detection of cytosine methylation in Burkholderia cenocepacia by single- molecule real- time sequencing and whole- genome bisulfite sequencing
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Can filaments, pellets and powder be used as feedstock to produce highly drug-loaded ethylene-vinyl acetate 3D printed tablets using extrusion-based additive manufacturing?
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Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs
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- Journal Article
- A1
- open access
PapRIV : a BV-2 microglial cell activating quorum sensing peptide
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Applications in medicine : mental health
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- Journal Article
- A2
- open access
Cov-MS : a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients
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- Journal Article
- A1
- open access
Model system parameters influence the sodium hypochlorite susceptibility of endodontic biofilms
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- Miscellaneous
- open access
Gebruik van antibiotica op geleide van CRP-bepaling bij een acute COPD-exacerbatie?
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- Miscellaneous
- open access
Nut van biomarkers bij de diagnostiek van een ambulante pneumonie
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Vancomycin dosing and therapeutic drug monitoring practices : guidelines versus real-life
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- Journal Article
- A1
- open access
The influence of equipment design and process parameters on granule breakage in a semi-continuous fluid bed dryer after continuous twin-screw wet granulation
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- Journal Article
- A1
- open access
Continuous twin screw granulation : impact of microcrystalline cellulose batch-to-batch variability during granulation and drying : a QbD approach
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- Journal Article
- A1
- open access
The cystic fibrosis lung microenvironment alters antibiotic activity : causes and effects
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Purpura fulminans : how varicella zoster can result in acquired protein S deficiency
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- Journal Article
- A1
- open access
Assessment of the effect of therapy in a rat model of glioblastoma using [18F]FDG and [18F]FCho PET compared to contrast-enhanced MRI
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- PhD Thesis
- open access
Towards an enhanced process understanding for a continuous pharmaceutical manufacturing process of tablets based on twin-screw wet granulation
(2021) -
Induction of antibiotic specialized metabolism by co-culturing in a collection of phyllosphere bacteria
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- Journal Article
- A1
- open access
Identifying critical binder attributes to facilitate binder selection for efficient formulation development in a continuous twin screw wet granulation process
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- Journal Article
- A1
- open access
Burkholderia bacteria produce multiple potentially novel molecules that inhibit carbapenem-resistant gram-negative bacterial pathogens
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Piezoelectric hybrid scaffolds mineralized with calcium carbonate for tissue engineering : analysis of local enzyme and small-molecule drug delivery, cell response and antibacterial performance
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Quorum sensing peptides as a novel microbiomal causative factor in promoting colorectal cancer metastasis : the EntF metabolite case
(2021) -
Biological activity and antimicrobial property of Cu/a-C:H nanocomposites and nanolayered coatings on titanium substrates
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Two-dimensional moisture content and size measurement of pharmaceutical granules after fluid bed drying using near-infrared chemical imaging
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Environmental risk assessment of the anthelmintic albendazole in Eastern Africa, based on a systematic review
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- Journal Article
- A1
- open access
Dietary muramidase degrades bacterial peptidoglycan to NOD-activating muramyl dipeptides and reduces duodenal inflammation in broiler chickens
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- Journal Article
- A1
- open access
Delta-mannitol to enable continuous twin-screw granulation of a highly dosed, poorly compactable formulation
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- Journal Article
- A1
- open access
Evaluation of an external lubrication system implemented in a compaction simulator
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A primary drying model-based comparison of conventional batch freeze-drying to continuous spin-freeze-drying for unit doses
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- Journal Article
- A1
- open access
Why is batch processing still dominating the biologics landscape? Towards an integrated continuous bioprocessing alternative
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- Journal Article
- A2
- open access
A simplified checklist for the visual inspection of finished pharmaceutical products : a way to empower frontline health workers in the fight against poor-quality medicines
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- Journal Article
- A1
- open access
Model-based optimization of the primary drying phase of oral lyophilizates
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- Journal Article
- A2
- open access
Non-leaching, highly biocompatible nanocellulose surfaces that efficiently resist fouling by bacteria in an artificial dermis model
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- Journal Article
- A1
- open access
A clinician’s perspective on yellow fever vaccine-associated neurotropic disease
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LC-MS compatible antiadsorption diluent for peptide analysis
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Prediction of tablet weight variability in continuous manufacturing
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Structural study of L-ascorbic acid 2-phosphate magnesium, a raw material in cell and tissue therapy
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- Journal Article
- A1
- open access
Characterization of simultaneous evolution of size and composition distributions using generalized aggregation population balance equation
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How to handle phenotypic diversity of pseudomonas aeruginosa for antibiotic susceptibility testing in cystic fibrosis patients?
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Investigation of Ag/a-C:H nanocomposite coatings on titanium for orthopedic applications
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Lyophilization and nebulization of pulmonary surfactant-coated nanogels for siRNA inhalation therapy
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Interplay between host-microbe and microbe-microbe interactions in cystic fibrosis
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Does the mode of dispersion determine the properties of dispersed Pseudomonas aeruginosa biofilm cells?
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- Journal Article
- A2
- open access
Biofilm dispersion : the key to biofilm eradication or opening Pandora’s box?
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- Journal Article
- A1
- open access
RhIR-regulated acyl-homoserine lactone quorum sensing in a cystic fibrosis isolate of Pseudomonas aeruginosa
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- Journal Article
- A1
- open access
The anti-microbial peptide (Lin-SB056-1)(2)-K reduces pro-inflammatory cytokine release through Interaction with Pseudomonas aeruginosa lipopolysaccharide
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- Journal Article
- A1
- open access
Bacterial interference with lactate dehydrogenase assay leads to an underestimation of cytotoxicity
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- Journal Article
- A1
- open access
Cutibacterium acnes phylotype I and II strains interact differently with human skin cells
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Exploring printed drug formulations for inkjet and stencil printing
(2020) -
An unexpected role for iNKT cells in skeletal muscle homeostasis
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Quorum sensing peptides and their interactions with the host
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- PhD Thesis
- open access
Cutibacterium acnes and acne vulgaris : how bad strains ruin it for everyone
(2020) -
- PhD Thesis
- open access
Exploring the effects of non-pathogenic respiratory microbiome members on inflammation in models of chronic airway disease
(2020) -
- Journal Article
- A1
- open access
Intra-individual dynamic comparison of 18F-PSMA-11 and 68Ga-PSMA-11 in LNCaP xenograft bearing mice
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- Journal Article
- A1
- open access
Synergistic antimicrobial activity of supplemented medical-grade honey against Pseudomonas aeruginosa biofilm formation and eradication
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Epigenetic control of gene expression in Burkholderia cenocepacia J2315 and K56-2
(2020) -
- PhD Thesis
- open access
Functional quality of selected antimalarial and antihelminthic medicines
(2020) -
The effects of ARBs, ACEis, and statins on clinical outcomes of COVID-19 infection among nursing home residents
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- PhD Thesis
- open access
Development and evaluation of next-generation pharmaceutical freeze-drying technologies
(2020) -
- Journal Article
- A1
- open access
MEK1/2 inhibition in murine heart and aorta after oral administration of refametinib supplemented drinking water
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Continuous twin screw granulation : robustness of lactose/MCC-based formulations
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- PhD Thesis
- open access
Quorum sensing peptides as possible brain-influencing microbiome mediators
(2020) -
- Journal Article
- A1
- open access
Development of a rat model for glioma-related epilepsy
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- PhD Thesis
- open access
Exploring diagnostic and therapeutic opportunities of LAT1-selective PET imaging in glioblastoma
(2020) -
Burkholderia : taxonomy and potential as antibiotic producers
(2020) -
Viscosity of API/fatty acid suspensions : pitfalls during analysis
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- Journal Article
- A2
- open access
Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm
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- Journal Article
- A1
- open access
DNA methylation epigenetically regulates gene expression in Burkholderia cenocepacia and controls biofilm formation, cell aggregation, and motility
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- Journal Article
- A1
- open access
Low iron-induced small RNA BrrF regulates central metabolism and oxidative stress responses in Burkholderia cenocepacia
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- Journal Article
- A2
- open access
Complete genome sequence of Pseudomonas aeruginosa Strain AA2 (LMG 27630), an early isolate recovered from the airway of a German cystic fibrosis patient
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- Journal Article
- A1
- open access
Burkholderia cepacia complex taxon K : where to split?
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The impact of formulation composition and process settings of traditional batch versus continuous freeze-drying on protein aggregation
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Application of polyvinyl acetate in an innovative formulation strategy for lyophilized orally disintegrating tablets
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Screening of pharmaceutical polymers for Extrusion-Based Additive Manufacturing of patient-tailored tablets
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Influence of binder attributes on binder effectiveness in a continuous twin screw wet granulation process via wet and dry binder addition
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- PhD Thesis
- open access
Amino acids in oncology diagnostics : development of new PET imaging probes targeting the glutamine transporter ASCT-2
(2020) -
- PhD Thesis
- open access
Quality by design for pharmaceutical hot melt extrusion via rheology and process analytical technology
(2020) -
- Journal Article
- A1
- open access
In-situ X-ray imaging of sublimating spin-frozen solutions
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In-line temperature measurement to improve the understanding of the wetting phase in twin-screw wet granulation and its use in process development
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- PhD Thesis
- open access
On the simulation of particle size distributions in continuous pharmaceutical wet granulation
(2020) -
- Journal Article
- A1
- open access
Radiosynthesis, in vitro and preliminary biological evaluation of [F-18]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino) butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron emission tomography tracer
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- Journal Article
- A1
- open access
Identification of the molecular determinants involved in antimicrobial activity of pseudodesmin A, a cyclic lipopeptide from the viscosin group
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- Journal Article
- A1
- open access
Influence of blood collection methods and long-term plasma storage on quorum-sensing peptide stability
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A role for iNKT cells in sarcopenia
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- Journal Article
- A1
- open access
Fabrication of microporous coatings on titanium implants with improved mechanical, antibacterial and cell-interactive properties
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- Journal Article
- A1
- open access
4D micro-computed X-ray tomography as a tool to determine critical process and product information of spin freeze-dried unit doses
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Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [18F]fluorophenylglutamine and [18F]fluorobiphenylglutamine
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- Journal Article
- A1
- open access
In vitro interaction of Pseudomonas aeruginosa biofilms with human peripheral blood mononuclear cells
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- Journal Article
- A1
- open access
Targeting Pseudomonas aeruginosa in the sputum of primary ciliary dyskinesia patients with a combinatorial strategy having antibacterial and anti-virulence potential
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- PhD Thesis
- open access
Modelling and experimentation on fluid bed drying of granules in the context of pharmaceutical continuous wet granulation
(2020) -
- PhD Thesis
- open access
Translational PET imaging in major depressive disorder and antidepressant therapies
(2020) -
- Journal Article
- A1
- open access
Surface functionalization with polyethylene glycol and polyethyleneimine improves the performance of graphene-based materials for safe and efficient intracellular delivery by laser-induced photoporation
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- Journal Article
- A1
- open access
Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets
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- Journal Article
- A1
- open access
Model-based optimisation and control strategy for the primary drying phase of a lyophilisation process
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- PhD Thesis
- open access
Leaving the biofilm in different ways : the properties of dispersed Pseudomonas aeruginosa biofilm cells
(2020) -
- Journal Article
- A1
- open access
Predicting pharmaceutical particle size distributions using kernel mean embedding
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Continuous twin screw granulation : impact of binder addition method and surfactants on granulation of a high-dosed, poorly soluble API
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Continuous twin screw granulation : a complex interplay between formulation properties, process settings and screw design
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Prilling of API/fatty acid suspensions : screening of additives for drug release modification
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New advances in the characterization of lyophilised orally disintegrating tablets
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Quorum sensing molecules as a novel microbial factor impacting muscle cells
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- PhD Thesis
- open access
Quality characterization of raw materials used in advanced therapy medicinal products : HEPES, APMg and albumin
(2020) -
- Journal Article
- A1
- open access
PEGylated mucus-penetrating nanocrystals for lung delivery of a new FtsZ inhibitor against Burkholderia cenocepacia infection
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- Journal Article
- A2
- open access
The future of biofilm research : report on the ‘2019 Biofilm Bash’
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- Journal Article
- A2
- open access
Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates