Department of Pharmaceutics

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong Chen (UGent) , Emily De Lombaerde (UGent) , Aimee-Rose Bugler-Lamb (UGent) , Zifu Zhong (UGent) , Martijn Schuijs (UGent) , Claudia Mariela Brenis Gómez (UGent) , Jamie De Baere (UGent) , Mark Gontsarik (UGent) , Heleen Lauwers (UGent) , Kim Deswarte (UGent) , et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.

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Immunogenic cell death as interplay between physical anticancer modalities and immunotherapy

Yanou Engelen (UGent) , Robin Demuynck (UGent) , Jana Ramon (UGent) , K. Breckpot, Stefaan De Smedt (UGent) , Guillaume Lajoinie, Kevin Braeckmans (UGent) , Dmitri Krysko (UGent) and Ine Lentacker (UGent)

(2025) JOURNAL OF CONTROLLED RELEASE. 384.

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Gentle and efficient engineering of primary human NK cells by photoporation with polydopamine nanosensitizers

Charlotte Hinnekens (UGent) , Jana Ramon (UGent) , M. Birben, W.T.V. Germeraad, A. Harizaj, Margo De Velder (UGent) , Stefaan De Smedt (UGent) , Bart Vandekerckhove (UGent) , Kevin Braeckmans (UGent) and Juan Fraire (UGent)

(2025) JOURNAL OF CONTROLLED RELEASE. 382.

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Development and validation of a high-throughput screening pipeline of compound libraries to target EMT

Sven Jonckheere, Joachim Taminau (UGent) , Jamie Adams, Jef Haerinck (UGent) , Jordy De Coninck (UGent) , Jeroen Verstappe (UGent) , Kato De Clercq (UGent) , Evelien Peeters (UGent) , Alexander Gheldof (UGent) , Eva De Smedt (UGent) , et al.

(2025) CELL DEATH AND DIFFERENTIATION.

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Journal Article
A1
open access

Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist

Hanne Verschuere (UGent) , Sabah Kasmi (UGent) , Lutz Nuhn (UGent) , Sènan Mickaël D'Almeida, Qiwen Zhu, Zifu Zhong (UGent) , Sandy Adjemian Catani (UGent) , Benoit Louage (UGent) , Jana De Vrieze, Haijun Yu, et al.

(2025) RSC ADVANCES. 15(15). p.11662-11674

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Miscellaneous

Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways

Sofie Rennen (UGent) , Victor Bosteels (UGent) , Clint De Nolf (UGent) , Greta Webb (UGent) , Karo Van Lil (UGent) , Sandra Maréchal (UGent) , Jessica Vetters (UGent) , Evelien Van De Velde (UGent) , Farzaneh Fayazpour (UGent) , Ria Roelandt (UGent) , et al.

(2025)

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HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia

Jonas De Kesel (UGent) , Igor Fijalkowski (UGent) , Tim Pieters (UGent) , Cristina Borin (UGent) , Kasper Thorhauge Christensen (UGent) , Manou Wittouck (UGent) , Jolien Van Laere (UGent) , Laura Guerrero (UGent) , Lindy Reunes (UGent) , Marino Caruso, et al.

(2025) BLOOD.

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Journal Article
A1
open access

Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD

Anneleen Heldens (UGent) , Milton Boaheng Antwi (UGent) , Louis Onghena (UGent) , Tim Meese (UGent) , Yannick Gansemans (UGent) , Joél Smet (UGent) , Ellen Dupont, Xavier Verhelst (UGent) , Sarah Raevens (UGent) , Hans Van Vlierberghe (UGent) , et al.

(2025) JHEP REPORTS. 7(6).

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Journal Article
A1
open access

Preclinical toxicological assessment of an α-galactosylceramide-adjuvanted mRNA cancer vaccine in Wistar Han rats and domestic pigs

Sofie Meulewaeter (UGent) , Margo De Velder (UGent) , Diethard Reckelbus (UGent) , Kevin Mwangi (UGent) , Thomas Ehouarne (UGent) , Ilke Aernout (UGent) , Yanou Engelen (UGent) , Fëllanza Halimi (UGent) , Isis Van herteryck (UGent) , Lobke De Bels (UGent) , et al.

(2025) MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 33(2).

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Classification of collagens via peptide ambiguation, in a paleoproteomic LC-MS/MS-based taxonomic pipeline

Ian Engels (UGent) , Alexandra Burnett (UGent) , Prudence Robert (UGent) , Camille Pironneau (UGent) , Grégory Abrams (UGent) , Robbin Bouwmeester (UGent) , Peter Van Der Plaetsen, Kévin Di Modica, Marcel Otte, Lawrence Guy Straus, et al.

(2025) JOURNAL OF PROTEOME RESEARCH. 24(4). p.1907-1925

Academic Bibliography

Department of Pharmaceutics

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Immunogenic cell death as interplay between physical anticancer modalities and immunotherapy

Gentle and efficient engineering of primary human NK cells by photoporation with polydopamine nanosensitizers

Development and validation of a high-throughput screening pipeline of compound libraries to target EMT

Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist

Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways

HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia

Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD

Preclinical toxicological assessment of an α-galactosylceramide-adjuvanted mRNA cancer vaccine in Wistar Han rats and domestic pigs

Classification of collagens via peptide ambiguation, in a paleoproteomic LC-MS/MS-based taxonomic pipeline

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