Academic Bibliography
https://biblio.ugent.be/
Ghent University Academic Bibliography2000-01-01T00:00+00:001monthlyOutcomes of Meek micrografting versus mesh grafting on deep dermal and full thickness (burn) wounds : study protocol for an intra-patient randomized controlled trial
https://biblio.ugent.be/publication/01HR7GF44MKXMYF9AX7ZWHNS0Q
Rijpma, Danielle Pijpe, AnoukClaes, KarelHoeksema, HendrikDe Decker, IgnaceVerbelen, Jozef van Zuijlen, PaulMonstrey, Stan Meij-de Vries, Annebeth2023IntroductionAutologous split thickness skin grafting is the standard-of-care for most deep dermal and full thickness skin defects. Historically, mesh grafting is used to expand skin grafts for smaller defects and other techniques such as Meek micrografting is used to enable expansion for larger skin defects. Yet, Meek micrografting is increasingly used for smaller skin defects as well. Both techniques are frequently used, especially in burn centers, but evidence on which one is preferable for relative smaller skin defects is lacking. Therefore, an intra-patient randomized controlled trial was designed to adequately compare multiple outcomes of the Meek micrografting and mesh grafting techniques. Materials and methodsA multicenter intra-patient controlled randomized trial is being performed in two burn centers (the Netherlands and Belgium) to compare multiple outcomes of Meek micrografting and mesh grafting burns or skin defects. Study registration number (NL74274.029.20). Adult patients with a (burn) wound and an indication for surgical excision and skin grafting were screened for inclusion. In total 70 patients will be included and the primary outcome is scar quality twelve months post-surgery assessed by the Patient and Observer Scar Assessment Scale. Moreover, graft take, re-epithelialization, infection rate, donor site size and patients' preference are also measured within hospital admission, on 3 months and 12 months post-surgery. DiscussionThis is the first randomized trial that is intra-patient controlled, which enables a proper comparison between both skin expansion techniques. The results of this study will contribute to the clarification of the indications of both techniques and ample attention is paid for the patients' opinion on the surgical treatment options.application/pdfhttps://biblio.ugent.be/publication/01HR7GF44MKXMYF9AX7ZWHNS0Qhttp://hdl.handle.net/1854/LU-01HR7GF44MKXMYF9AX7ZWHNS0Qhttp://doi.org/10.1371/journal.pone.0281347https://biblio.ugent.be/publication/01HR7GF44MKXMYF9AX7ZWHNS0Q/file/01HR7MB3QCM8ZFJ9DM7BBVS19QengPublic Library ScienceCreative Commons Attribution 4.0 International Public License (CC-BY 4.0)info:eu-repo/semantics/closedAccessPLOS ONEISSN: 1932-6203Medicine and Health SciencesSCARSMETERLIFEOutcomes of Meek micrografting versus mesh grafting on deep dermal and full thickness (burn) wounds : study protocol for an intra-patient randomized controlled trialjournalArticleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionThe process to obtain reimbursement for enzymatic debridement in clinically deep burns
https://biblio.ugent.be/publication/8736612
Claes, KarelHoeksema, HendrikLafaire, CynthiaDe Cuyper, LieveDe Groote, KatrienVyncke, TomDe Decker, IgnaceVerbelen, JozefDe Coninck, PetraDepypere, BernardMonstrey, Stan2023Introduction Burn eschar removal by enzymatic debridement with NexoBrid(R) (EDNX) results in a maximum preservation of all viable tissue, which is the main advantage over traditional tangential excision. The authors participated in a marketing authorization holder process to obtain reimbursement from the national health authorities in Belgium. Material and methods The reimbursement process consisted of three phases, as specified by the reimbursement regulations required by the Belgian National Institute for Health and Disability Insurance (NIHDI). Results Forty-one patients with clinically deep 2nd and 3rd degree burns, treated with EDNX in two Belgian burn centers, were included in the registry for the first phase of the reimbursement process. The total success rate of the EDNX treatment was 95.1% (39/41). Over half of the burn wounds treated with NexoBrid(R) (55.2%) did not require any additional surgical debridement or skin grafting. To obtain definitive reimbursement, an extra 16 patients were included. In this population, 51.4% did not require any surgical intervention. The total success rate of the EDNX debridement in this group was 100%. Based on an estimated market share of 12% and around 75 patients in the third year after final reimbursement, a market access consultant calculated that NexoBrid(R) will realize yearly savings for the Belgian Healthcare budget of at least euro30.000. Conclusion Based on the results of this Belgian registry study in combination with the yearly healthcare budget savings, the NIHDI granted a final reimbursement for EDNX treatment in adults, endorsed by the Minister of Health on November 5(th), 2019.application/pdfhttps://biblio.ugent.be/publication/8736612http://hdl.handle.net/1854/LU-8736612http://doi.org/10.1080/00015458.2021.2006408https://biblio.ugent.be/publication/8736612/file/01HSTR0YQJB1ANKSF44TWXRZE2engNo license (in copyright)info:eu-repo/semantics/restrictedAccessACTA CHIRURGICA BELGICAISSN: 0001-5458Medicine and Health SciencesGeneral MedicineSurgeryBurnEnzymatic debridementreimbursementbudgetary controlmanaged entry agreementESCHAR REMOVALDEPTHPRESERVATIONNEXOBRID(R)TISSUEThe process to obtain reimbursement for enzymatic debridement in clinically deep burnsjournalArticleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionHelpful hints in deciding what and when to operate after enzymatic debridement
https://biblio.ugent.be/publication/01GRBC9TX0F4HJ91P1CXYTK8W1
Claes, KarelDe Decker, IgnaceMonstrey, StanShoham, YaronVyncke, TomDepypere, BernardDe Wolf, EdwardDecuypere, FienLannau, BerndHoeksema, Hendrik2023application/pdfhttps://biblio.ugent.be/publication/01GRBC9TX0F4HJ91P1CXYTK8W1http://hdl.handle.net/1854/LU-01GRBC9TX0F4HJ91P1CXYTK8W1http://doi.org/10.1016/j.burns.2022.01.004https://biblio.ugent.be/publication/01GRBC9TX0F4HJ91P1CXYTK8W1/file/01GRBD7VZAVHRMN9DBZ2TW0VG1engElsevier BVNo license (in copyright)info:eu-repo/semantics/restrictedAccessBURNSISSN: 0305-4179ISSN: 1879-1409Medicine and Health SciencesCritical Care and Intensive Care MedicineEmergency MedicineGeneral MedicineSurgeryWound bed evaluationArea of interestLaser Doppler imagingEnzymatic debridementBurnHelpful hints in deciding what and when to operate after enzymatic debridementjournalArticleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPrinciples and outcomes of gender-affirming vaginoplasty
https://biblio.ugent.be/publication/01HR7GF44NXZYPSEC4S5JHX9RX
Morrison, Shane D.Claes, KarelMorris, Martin P.Monstrey, StanHoebeke, PietBuncamper, Marlon2023Vaginoplasty is the most frequently performed gender-affirming genital surgery for gender-diverse people with genital gender incongruence. The procedure is performed to create an aesthetic and functional vulva and vaginal canal that enables receptive intercourse, erogenous clitoral sensation and a downward-directed urine stream. Penile inversion vaginoplasty (PIV) is a single surgical procedure involving anatomical component rearrangement of the penis and scrotum that enables many patients to meet these anatomical goals. Other options include minimal-depth, peritoneal and intestinal vaginoplasty. Patient quality of life has been shown to improve drastically after vaginoplasty, but complication rates have been documented to be as high as 70%. Fortunately, most complications do not alter long-term postoperative clinical outcomes and can be managed without surgical intervention in the acute perioperative phase. However, major complications, such as rectal injury, rectovaginal fistula, and urethral or introital stenosis can substantially affect the patient experience. Innovations in surgical approaches and techniques have demonstrated promising early results for reducing complications and augmenting vaginal depth, but long-term data are scarce.
In this Review, the authors describe the evolution of vaginoplasty including surgical techniques, complications, and clinical and patient-reported outcomes and consider current controversies in techniques and areas for improvement.application/pdfhttps://biblio.ugent.be/publication/01HR7GF44NXZYPSEC4S5JHX9RXhttp://hdl.handle.net/1854/LU-01HR7GF44NXZYPSEC4S5JHX9RXhttp://doi.org/10.1038/s41585-022-00705-yhttps://biblio.ugent.be/publication/01HR7GF44NXZYPSEC4S5JHX9RX/file/01HR9GCCVE3EXGKYXVA9CP2KC9engNature PortfolioNo license (in copyright)info:eu-repo/semantics/restrictedAccessNATURE REVIEWS UROLOGYISSN: 1759-4812ISSN: 1759-4820Medicine and Health SciencesPENILE INVERSION VAGINOPLASTYSEX REASSIGNMENT SURGERYSIGMOID COLON VAGINOPLASTYTO-FEMALE TRANSSEXUALISMTHICKNESS SKIN-GRAFTTERM-FOLLOW-UPSENSORY DETECTION THRESHOLDSRECTO-NEOVAGINAL FISTULATRANSGENDER WOMENVAGINAL RECONSTRUCTIONPrinciples and outcomes of gender-affirming vaginoplastyjournalArticleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionBurn management: From survival to quality of survival
https://biblio.ugent.be/publication/01HRA00BEDBWAA28FFQDXFSJJV
Claes, KarelDe Decker, IgnaceBlot, Stijn2023application/pdfhttps://biblio.ugent.be/publication/01HRA00BEDBWAA28FFQDXFSJJVhttp://hdl.handle.net/1854/LU-01HRA00BEDBWAA28FFQDXFSJJVhttp://doi.org/10.1016/j.iccn.2023.103451https://biblio.ugent.be/publication/01HRA00BEDBWAA28FFQDXFSJJV/file/01HRA0MQ1RDGQ4Y0GE79SP74QRengELSEVIER SCI LTDNo license (in copyright)info:eu-repo/semantics/restrictedAccessINTENSIVE AND CRITICAL CARE NURSINGISSN: 0964-3397ISSN: 1532-4036GUIDELINESBurn management: From survival to quality of survivalmiscinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersion