Academic Bibliography
https://biblio.ugent.be/
Ghent University Academic Bibliography2000-01-01T00:00+00:001monthlyDevelopment of an atrial transseptal puncture procedure in horses to access the left heart: An ultrasound‐guided jugular vein and transhepatic approach
https://biblio.ugent.be/publication/01HSWY78EJ9AV3JY8V0WB6J7H3
Vernemmen, IngridVan Steenkiste, GlennBuschmann, EvaCornelis, KristoffSchauvliege, StijnIbrahim, LaraDecloedt, Anneliesvan Loon, Gunther2024info:eu-repo/date/embargoEnd/2025-03-26Background: Radiofrequency ablation has been successfully applied to treat right atrial arrhythmias in horses. Ablation of left‐sided arrhythmias requires a retrograde transarterial approach which is complicated. In human medicine, the left atrium is accessed through transseptal puncture (TSP) of the fossa ovalis (FO) using a caudal approach via the femoral vein. Objectives: To develop a zero fluoroscopy TSP technique for horses using a jugular vein (cranial) and transhepatic (caudal) approach. Study design: In vivo experimental study. Methods: Transseptal puncture was performed in 18 horses admitted for euthanasia and donated for scientific research under general anaesthesia: using a jugular vein approach (10 horses), a transhepatic approach (2 horses) or both (6 horses). Radiofrequency energy was applied on a guidewire to perforate the FO and allow sheath advancement under intracardiac and transthoracic echocardiographic guidance. Puncture lesions were inspected post‐mortem. Results: Transseptal puncture was successful in 17/18 horses, of which 15/16 jugular vein approaches and 5/8 transhepatic approaches. Failure was due to technical malfunction, inability to advance the guidewire toward the heart and inability to advance the sheath through the FO. Intracardiac echocardiography was essential to safely guide the puncture process. Atrial arrhythmias caused by the TSP occurred in 13/18 horses. Puncture lesions were found in the right atrium in the FO region, and left atrium ventral to pulmonary vein ostium III. Main limitations: Because in several horses two approaches were tested consecutively, it cannot be excluded that the second TSP was performed at the previous puncture site. Due to the developmental nature of the study the approaches were not randomised and did not allow comparison. Conclusion: Transseptal puncture is feasible in horses using ultrasound guidance and allows for electrophysiological exploration of the left heart. Further studies are needed to evaluate post‐operative follow‐up.application/pdfhttps://biblio.ugent.be/publication/01HSWY78EJ9AV3JY8V0WB6J7H3http://hdl.handle.net/1854/LU-01HSWY78EJ9AV3JY8V0WB6J7H3http://doi.org/10.1111/evj.14084https://biblio.ugent.be/publication/01HSWY78EJ9AV3JY8V0WB6J7H3/file/01HSX04N3Y8FH8W147G4DA2S2RengWileyInformation pendinginfo:eu-repo/semantics/embargoedAccessEquine Veterinary JournalISSN: 0425-1644ISSN: 2042-3306Veterinary SciencesGeneral Medicineablationhorseinterventional cardiologyintracardiac echocardiographyleft heart catheterisationmappingzero-fluoroscopyDevelopment of an atrial transseptal puncture procedure in horses to access the left heart: An ultrasound‐guided jugular vein and transhepatic approachjournalArticleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionDataset: Development of transseptal puncture in horses EVJ
https://biblio.ugent.be/publication/01HGK1WC6FR30879WNZEK73Z5A
Vernemmen, IngridVan Steenkiste, GlennBuschmann, EvaCornelis, KristoffSchauvliege, StijnIbrahim, LaraDecloedt, Anneliesvan Loon, Gunther2023<b>Background:</b> Radiofrequency ablation has been successfully applied to treat right atrial arrhythmias in horses. Ablation of left-sided arrhythmias requires a retrograde transarterial approach which is complicated. In human medicine, the left atrium is accessed through transseptal puncture (TSP) of the fossa ovalis (FO) using a caudal approach via the femoral vein.<b>Objectives:</b> To develop a zero fluoroscopy TSP technique for horses using a jugular vein (cranial) and transhepatic (caudal) approach.<b>Study design:</b> <i>In vivo</i><b><i> </i></b>experimental study.<b>Methods:</b> Transseptal puncture was performed in 18 horses admitted for euthanasia and donated for scientific research under general anaesthesia: using a jugular vein approach (ten horses), a transhepatic approach (two horses) or both (six horses). Radiofrequency energy was applied on a guidewire to perforate the FO and allow sheath advancement under intracardiac and transthoracic echocardiographic guidance. Puncture lesions were inspected post-mortem.<b>Results: </b>Transseptal puncture was successful in 17/18 horses, of which 15/16 jugular vein approaches and 5/8 transhepatic approaches. Failure was due to technical malfunction, inability to advance the guidewire towards the heart and inability to advance the sheath through the FO. Intracardiac echocardiography was essential to safely guide the puncture process. Atrial arrhythmias caused by the TSP occurred in 13/18 horses. Puncture lesions were found in the right atrium in the FO region, and in the left atrium ventral to pulmonary vein ostium III.<b>Main limitations:</b> As in several horses two approaches were tested consecutively, it cannot be excluded that the second TSP was performed at the previous puncture site. Due to the developmental nature of the study the approaches were not randomized and did not allow comparison.<b>Conclusion: </b>Transseptal puncture is feasible in horses using ultrasound guidance and allows for electrophysiological exploration of the left heart. Further studies are needed to evaluate post-operative follow-up.https://biblio.ugent.be/publication/01HGK1WC6FR30879WNZEK73Z5Ahttp://hdl.handle.net/1854/LU-01HGK1WC6FR30879WNZEK73Z5Ahttp://doi.org/10.6084/M9.FIGSHARE.24681351engfigshareCreative Commons Attribution 4.0 International Public License (CC-BY 4.0)Transseptal punctureHorsesInterventional cardiologyDataset: Development of transseptal puncture in horses EVJresearchDatainfo:eu-repo/semantics/otherDevelopment of a three-dimensional computer model of the equine heart using a polyurethane casting technique and in vivo contrast-enhanced computed tomography
https://biblio.ugent.be/publication/01HHP7W9W5X60YKV9WC1QME8WD
Vernemmen, IngridVan Steenkiste, GlennHauspie, StijnDe Lange, LisaBuschmann, EvaSchauvliege, StijnVan Den Broeck, WimDecloedt, AnneliesVanderperren, Katrienvan Loon, Gunther2024info:eu-repo/date/embargoEnd/2024-07-07Introduction/objectives: Insight into the three-dimensional (3D) anatomy of the equine heart is essential in veterinary education and to develop minimally-invasive intracardiac procedures. The aim was to create a 3D computer model simulating the in vivo anatomy of the adult equine heart.
Animals: Ten horses and five ponies.
Materials and Methods: Ten horses, euthanized for non-cardiovascular reasons, were used for in situ cardiac casting with polyurethane foam and subsequent computed tomography (CT) of the excised heart. In five anaesthetized ponies, a contrast-enhanced ECG-gated CT protocol was optimized to image the entire heart. Dedicated image processing software was used to create 3D models of all CT scans derived from both methods. Resulting models were compared regarding relative proportions, detail, and ease of segmentation.
Results: The casting protocol produced high detail but compliant structures, such as the pulmonary trunk, were disproportionally expanded by the foam. Optimization of the contrast-enhanced CT protocol, especially adding a delayed phase for visualization of the cardiac veins, resulted in sufficiently detailed CT images to create an anatomically correct 3D model of the pony heart. Rescaling was needed to obtain a horse-sized model.
Conclusions: Three-dimensional computer models based on contrast-enhanced CT images appeared superior to those based on casted hearts to represent the in vivo situation and are preferred to obtain an anatomically correct heart model useful for education, client communication and research purposes. Scaling was however necessary to obtain an approximation of an adult horse heart, as cardiac CT imaging is restricted by thoracic size.application/vnd.openxmlformats-officedocument.wordprocessingml.documenthttps://biblio.ugent.be/publication/01HHP7W9W5X60YKV9WC1QME8WDhttp://hdl.handle.net/1854/LU-01HHP7W9W5X60YKV9WC1QME8WDhttp://doi.org/10.1016/j.jvc.2023.11.014https://biblio.ugent.be/publication/01HHP7W9W5X60YKV9WC1QME8WD/file/01HHP8SWRT1C4EYWK86YQBSYM3engNo license (in copyright)info:eu-repo/semantics/embargoedAccessJOURNAL OF VETERINARY CARDIOLOGYISSN: 1760-2734ISSN: 1875-0834Veterinary SciencesAngiographycardiac segmentationheart phantom3D printingin silico cardiac modelPERCUTANEOUS TRANSCATHETER CLOSUREPATENT DUCTUS-ARTERIOSUSAORTO-CARDIAC FISTULAECHOCARDIOGRAPHYANEURYSMANATOMYHORSESDevelopment of a three-dimensional computer model of the equine heart using a polyurethane casting technique and in vivo contrast-enhanced computed tomographyjournalArticleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionDataset: Successful caudal vena cava and pulmonary vein isolation in healthy horses using 3D electro-anatomical mapping and a contact force-guided abaltion system
https://biblio.ugent.be/publication/01HGWKZEHH2K46ZD26NMG0XJXP
Buschmann, EvaVan Steenkiste, GlennDuytschaever, MattiasBoussy, TimothyVernemmen, IngridIbrahim, LaraSchauvliege, StijnDecloedt, Anneliesvan Loon, Gunther2023Background: Recently, treatment of equine atrial tachycardia by three-dimensional electro-anatomical mapping (3D EAM) and radiofrequency catheter ablation (RFCA) has been described. Myocardial sleeves in the caudal vena cava and pulmonary veins are a potential trigger for initiation and perpetuation of atrial tachycardia and atrial fibrillation in the horse. Isolation of these myocardial sleeves by RFCA may be an effective treatment for these arrhythmias.Objectives: To describe the feasibility of 3D EAM and RFCA to isolate caudal vena cava and pulmonary veins in adult horses using 3D mapping and a contact force (CF)-guided ablation system.Study Design: In vivo experiment.Methods: 3D EAM and RFCA was performed in five horses without cardiovascular disease under general anaesthesia, using the CF-guided system CARTO®3. Point-by-point RFCA aimed for isolation of caudal vena cava and pulmonary veins. Radiofrequency energy was delivered in power-controlled mode with a target power of 45 W, CF between 10-15 g and 30 ml/min irrigation rate, until an ablation-index of 450-500 was reached.Results: In the right atrium, myocardial sleeves of the caudal vena cava were isolated (n=5). In the left atrium, isolation of ostium II (n=3), ostium III (n=1) and ostium I, II and III <i>en bloc </i>(n=1) was performed. Successful isolation was confirmed by entrance and exit block.Main limitations: Horses were euthanized at the end of the procedure, so long term effects such as potential reconnection of isolated veins could not be studied.Conclusions: This is the first description of 3D EAM and RFCA with CARTO® 3 in horses, thereby showing the technical feasibility and successful caudal vena cava and pulmonary vein isolation. CF measurement allowed monitoring of catheter-tissue contact, resulting in efficient acute lesion creation as confirmed by entrance and exit block. This is a promising treatment for cardiac arrhythmias in horses.https://biblio.ugent.be/publication/01HGWKZEHH2K46ZD26NMG0XJXPhttp://hdl.handle.net/1854/LU-01HGWKZEHH2K46ZD26NMG0XJXPhttp://doi.org/10.6084/M9.FIGSHARE.24745281engfigshareCreative Commons Attribution 4.0 International Public License (CC-BY 4.0)Horses3D electro-anatomical mappingElectrophysiology/arrhythmiaRadiofrequency ablation, RFADataset: Successful caudal vena cava and pulmonary vein isolation in healthy horses using 3D electro-anatomical mapping and a contact force-guided abaltion systemresearchDatainfo:eu-repo/semantics/other